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Antonio del Sol Mesa

Antonio del Sol Mesa

Associate professor in Bioinformatics

Research Topics Computational Biology, Systems Biology, Biological Networks, Parkinson's disease research, Mathematical modeling, Bioinformatics
Faculty or Centre Luxembourg Centre for Systems Biomedicine
Research Unit Sciences de la Vie
Postal Address Université du Luxembourg
6, avenue du Swing
L-4367 Belvaux
Campus Office BioTech II, 0.04C
Email
Telephone (+352) 46 66 44 6982
Video Ass. Prof. Dr. Antonio del Sol
Ass. Prof. Dr. Antonio del Sol
 
Ass. Prof. Dr. Antonio del Sol

Principal Investigator in the Computational Biology group (del Sol Lab)

Last updated on: Wednesday, 09 July 2014

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2016

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See detailGene Regulatory Network Inference of Immunoresponsive Gene 1 (IRG1) Identifies Interferon Regulatory Factor 1 (IRF1) as Its Transcriptional Regulator in Mammalian Macrophages
Antony, Paul; Tallam, Aravind; Perumal, Thanneer Malai; Jäger, Christian; Fritz, Joëlle; Balling, Rudi; del Sol Mesa, Antonio; Michelucci, Alessandro; Vallar, Laurent

in PLoS ONE (2016)

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See detailProx1 is required for oligodendrocyte cell identity in adult neural stem cells of the subventricular zone
Bunk, Eva; Ertaylan, Goekhan; Ortega, Felipe; Pavlou, Maria; Gonzalez Cano, Laura; Stergiopoulos, Athanasios; Safaiyan, Shima; Voels, Sandra; van Cann, Marianne; Politis, Panagiotis; Berninger, Benedikt; del Sol Mesa, Antonio; Schwamborn, Jens Christian

in Stem Cells (2016)

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See detailPrediction of disease-gene-drug relationships following a differential network analysis
del Sol Mesa, Antonio; Zickenrott, Sascha; Espinosa Angarica, Vladimir

in Cell Death & Disease (2016), 7

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2015

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See detailTRIM32 modulates pluripotency entry and exit by directly regulating Oct4 stability
Bahnassawy, Lamia’a; Perumal, Thanneer; Gonzalez Cano, Laura; Hillje, Anna-Lena; Taher, Leila; Makalowski, Wojciech; Suzuki, Yutaka; Fuellen, Georg; del Sol Mesa, Antonio; Schwamborn, Jens Christian

in Scientific Reports (2015)

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See detailTranscriptome of human foetal heart compared with cardiomyocytes from pluripotent stem cells
del Sol Mesa, Antonio; Mummery, Christine

in Development (2015)

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See detailStemness of the hybrid Epithelial/Mesenchymal State in Breast Cancer and Its Association with Poor Survival.
Grosse-Wilde, Anne; Fouquier d'Hérouël, Aymeric; McIntosh, Ellie; Ertaylan, Gökhan; Skupin, Alexander; Kuestner, Rolf E.; del Sol Mesa, Antonio; Walters, Kathie-Anne; Huang, Sui

in PLoS ONE (2015), 10(5), 0126522

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See detailIdentification of large-scale genomic variation in cancer genomes using in silico reference models
Killcoyne, Sarah; del Sol Mesa, Antonio

in Nucleic Acids Research (2015)

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See detailThe RNA helicase DDX6 regulates cell-fate specification in neural stem cells via miRNAs
Nicklas, Sarah; Okawa, Satoshi; Hillje, Anna-Lena; Gonzalez Cano, Laura; del Sol Mesa, Antonio; Schwamborn, Jens Christian

in Nucleic Acids Research (2015)

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See detailA computational strategy for predicting lineage specifiers in stem cell subpopulations
Okawa, Satoshi; del Sol Mesa, Antonio

in Stem Cell Research (2015)

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See detailA differential network analysis approach for lineage specifier prediction in stem cell subpopulations
Okawa, Satoshi; Espinosa Angarica, Vladimir; Lemischka, Ihor; Moore, Kateri; del Sol Mesa, Antonio

in Systems Biology and Applications (2015)

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See detailDiscrete Logic Modelling Optimization to Contextualize Prior Knowledge Networks Using PRUNET
Rodriguez, Ana; Crespo, Isaac; Androsova, Ganna; del Sol Mesa, Antonio

in PLoS ONE (2015), 10(6), 0127216

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2014

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See detailA population shift view of cellular reprogramming
del Sol Mesa, Antonio

in Stem Cells (2014)

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See detailGene regulatory network analysis reveals differences in site-specific cell fate determination in mammalian brain
Ertaylan, Gökhan; Okawa, Satoshi; Schwamborn, Jens Christian; del Sol Mesa, Antonio

in Frontiers in Cellular Neuroscience (2014)

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See detailIntegrating Pathways of Parkinson's Disease in a Molecular Interaction Map
Fujita, Kazuhiro A.; Ostaszewski, Marek; Matsuoka, Yukiko; Ghosh, Samik; Glaab, Enrico; Trefois, Christophe; Crespo, Isaac; Perumal, Thanneer Malai; Jurkowski, Wiktor; Antony, Paul; Diederich, Nico; Buttini, Manuel; Kodama, Akihiko; Satagopam, Venkata; Eifes, Serge; del Sol Mesa, Antonio; Schneider, Reinhard; Kitano, Hiroaki; Balling, Rudi

in Molecular Neurobiology (2014)

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See detailFIGG: Simulating populations of whole genome sequences for heterogeneous data analyses.
Killcoyne, Sarah; del Sol Mesa, Antonio

in BMC Bioinformatics (2014), 15(1),

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See detailModelling Fanconi anemia pathogenesis and therapeutics using integration-free patient-derived iPSCs.
Liu, Guang-Hui; Suzuki, Keiichiro; Li, Mo; Qu, Jing; Montserrat, Nuria; Tarantino, Carolina; Gu, Ying; Yi, Fei; Xu, Xiuling; Zhang, Weiqi; Ruiz, Sergio; Plongthongkum, Nongluk; Zhang, Kun; Masuda, Shigeo; Nivet, Emmanuel; Tsunekawa, Yuji; Soligalla, Rupa Devi; Goebl, April; Aizawa, Emi; Kim, Na Young; Kim, Jessica; Dubova, Ilir; Li, Ying; Ren, Ruotong; Benner, Chris; del Sol Mesa, Antonio; Bueren, Juan; Trujillo, Juan Pablo; Surralles, Jordi; Cappelli, Enrico; Dufour, Carlo; Esteban, Concepcion Rodriguez; Izpisua Belmonte, Juan Carlos

in Nature communications (2014), 5

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See detailHippocampal extracellular matrix levels and stochasticity in synaptic protein expression increase with age and are associated with age-dependent cognitive decline.
Vegh, Marlene J.; Rausell, Antonio; Loos, Maarten; Heldring, Celine M.; Jurkowski, Wiktor; van Nierop, Pim; Paliukovich, Iryna; Li, Ka Wan; del Sol Mesa, Antonio; Smit, August B.; Spijker, Sabine; van Kesteren, Ronald E.

in Molecular & cellular proteomics : MCP (2014)

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2013

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See detailPredicting missing expression values in gene regulatory networks using a discrete logic modeling optimization guided by network stable states
Crespo, Isaac; Krishna, Abhimanyu; Le Béchec, Antony; del Sol Mesa, Antonio; *Co-first-authors

in Nucleic Acids Research (2013), 41(1), 8

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See detailThe Parkinson's Disease Map: A Framework for Integration, Curation and Exploration of Disease-related Pathways
Ostaszewski, Marek; Fujita, Kazuhiro; Matsuoka, Yukiko; Ghosh, Samik; Glaab, Enrico; Trefois, Christophe; Crespo, Isaac; Perumal, Thanneer Malai; Jurkowski, Wiktor; Antony, Paul; Diederich, Nico; Buttini, Manuel; Kolodkin, Alexey; Kodama, Akihiko; Satagopam, Venkata; Biryukov, Maria; Eifes, Serge; del Sol Mesa, Antonio; Schneider, Reinhard; Kitano, Hiroaki; Balling, Rudi

Poster (2013, March 09)

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2012

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See detailGene regulatory network analysis supports inflammation as a key neurodegeneration process in prion disease.
Crespo, Isaac; Rump, Kirsten; Jurkowski, Wiktor; Kitano, H.; del Sol Mesa, Antonio

in BMC Systems Biology (2012), 6(132),

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See detailA Novel Network Integrating a miRNA-203/SNAI1 Feedback Loop which Regulates Epithelial to Mesenchymal Transition.
Moes, Michèle; Le Béchec, Antony; Crespo, Isaac; Laurini, Christina; Halavatyi, Aliaksandr; Vetter, G.; del Sol Mesa, Antonio; Friederich, A.

in PLoS ONE (2012), 7(4), 35440

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See detailEvolutionary conservation and network structure characterize genes of phenotypic relevance for mitosis in human
Ostaszewski, Marek; Eifes, Serge; del Sol Mesa, Antonio

in PLoS ONE (2012), 7(5), 36488

See detailConstructing a comprehensive map of Parkinson’s disease to elucidate underlying mechanisms of its multifaceted molecular pathology
Trefois, Christophe; Fujita, A. K.; Ostaszewski, Marek; Matsuoka, Yukiko; Ghosh, Samic; Glaab, Enrico; Crespo, Isaac; Perumal, T. M.; Jurkowski, Wiktor; Antony, Paul; Diederich, Nico; Buttini, Manuel; Kodama, Akihiko; Satagopam, Venkata; Eifes, Serge; del Sol Mesa, Antonio; Schneider, Reinhard; Kitano, Hiroaki; Balling, Rudi

Poster (2012, August)

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2011

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See detailPPARγ population shift produces disease-related changes in molecular networks associated with metabolic syndrome
Jurkowski, Wiktor; Roomp, Kirsten; Crespo, Isaac; Schneider, Jochen; del Sol Mesa, Antonio

in Cell Death & Disease (2011), 2(8), 192

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2010

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See detailDiseases as network perturbations
del Sol Mesa, Antonio; Balling, Rudi; Hood, Leroy; Galas, David J.

in Current Opinion in Biotechnology (2010), 21(4), 566-571

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2009

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See detailMethyl side-chain dynamics prediction based on protein structure
Carbonell, P.; del Sol Mesa, Antonio

in Bioinformatics (2009), 25(19), 2552-8

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See detailEnergetic determinants of protein binding specificity: insights into protein interaction networks
Carbonell, P.; Nussinov, R.; del Sol Mesa, Antonio

in Proteomics (2009), 9(7), 1744-53

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See detailResidues crucial for maintaining short paths in network communication mediate signaling in proteins
del Sol Mesa, Antonio; Fujihashi, Hirotomo; Amoros, Dolors; Nussinov, Ruth

in Molecular Systems Biology (2009), 2

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See detailThe origin of Allosteric Modulation: Multiple Pre-existing Pathways Selection
del Sol Mesa, Antonio; Tsai, Chung-Jung; Ma, Buyong; Nussinov, Ruth

in Structure (2009), 17(8), 1042-1050

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See detailProtein allostery, signal transmission and dynamics: a classification scheme of allosteric mechanisms
Tsai, C. J.; del Sol Mesa, Antonio; Nussinov, R.

in Molecular Biosystems (2009), 5(3), 207-16

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2008

See detailAllostery: absence of a change in shape does not imply that allostery is not at play.
Tsai, Chung-Jung; del Sol Mesa, Antonio; Nussinov, Ruth

in Journal of molecular biology (2008), 378(1), 1-11

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2007

See detailModular architecture of protein structures and allosteric communications: potential implications for signaling proteins and regulatory linkages.
del Sol Mesa, Antonio; Arauzo-Bravo, Marcos J.; Amoros, Dolors; Nussinov, Ruth

in Genome biology (2007), 8(5), 92

See detailThe modular organization of domain structures: insights into protein-protein binding.
del Sol Mesa, Antonio; Carbonell, Pablo

in PLoS computational biology (2007), 3(12), 239

See detailLigand binding and circular permutation modify residue interaction network in DHFR.
Hu, Zengjian; Bowen, Donnell; Southerland, William M.; del Sol Mesa, Antonio; Pan, Yongping; Nussinov, Ruth; Ma, Buyong

in PLoS computational biology (2007), 3(6), 117

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2006

See detailTreeDet: a web server to explore sequence space.
Carro, Angel; Tress, Michael; de Juan, David; Pazos, Florencio; Lopez-Romero, Pedro; del Sol Mesa, Antonio; Valencia, Alfonso; Rojas, Ana M.

in Nucleic acids research (2006), 34(Web Server issue), 110-5

See detailResidue centrality, functionally important residues, and active site shape: analysis of enzyme and non-enzyme families.
del Sol Mesa, Antonio; Fujihashi, Hirotomo; Amoros, Dolors; Nussinov, Ruth

in Protein science : a publication of the Protein Society (2006), 15(9), 2120-8

See detailResidues crucial for maintaining short paths in network communication mediate signaling in proteins.
del Sol Mesa, Antonio; Fujihashi, Hirotomo; Amoros, Dolors; Nussinov, Ruth

in Molecular systems biology (2006), 2

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2005

See detailA framework for computational and experimental methods: identifying dimerization residues in CCR chemokine receptors.
de Juan, David; Mellado, Mario; Rodriguez-Frade, Jose Miguel; Hernanz-Falcon, Patricia; Serrano, Antonio; del Sol Mesa, Antonio; Valencia, Alfonso; Martinez-A, Carlos; Rojas, Ana Maria

in Bioinformatics (Oxford, England) (2005), 21 Suppl 2

See detailTopology of small-world networks of protein-protein complex structures.
del Sol Mesa, Antonio; Fujihashi, Hirotomo; O'Meara, Paul

in Bioinformatics (Oxford, England) (2005), 21(8), 1311-5

See detailSmall-world network approach to identify key residues in protein-protein interaction.
del Sol Mesa, Antonio; O'Meara, Paul

in Proteins (2005), 58(3), 672-82

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2004

See detailIdentification of amino acid residues crucial for chemokine receptor dimerization.
Hernanz-Falcon, Patricia; Rodriguez-Frade, Jose Miguel; Serrano, Antonio; Juan, David; del Sol Mesa, Antonio; Soriano, Silvia F.; Roncal, Fernando; Gomez, Lucio; Valencia, Alfonso; Martinez-A, Carlos; Mellado, Mario

in Nature immunology (2004), 5(2), 216-23

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2003

See detailAutomatic methods for predicting functionally important residues.
del Sol Mesa, Antonio; Pazos, Florencio; Valencia, Alfonso

in Journal of molecular biology (2003), 326(4), 1289-302

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2002

See detailConnection between type B (or C) and F factorizations and construction of algebras
del Sol Mesa, Antonio

in Journal of Physics : A Mathematical & General (2002)

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2000

See detailConnection between type A and E factorizations and construction of satellite algebras
del Sol Mesa, Antonio

in Journal of Physics : A Mathematical & General (2000)

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1999

See detailA class of exactly solvable matrix models
del Sol Mesa, Antonio

in Journal of Mathematical Chemistry (1999)

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1998

See detailGeneralized Morse potential: Symmetry and satellite potentials
del Sol Mesa, Antonio

in Journal of Physics : A Mathematical & General (1998)

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1997

See detailOrdering problems in fermionic relativistic quantum mechanics
del Sol Mesa, Antonio

in International Journal of Modern Physics A : Particles & Fields, Gravitation, Cosmology, Nuclear Physics (1997)

See detailSupermultiplicity and the relativistic coulomb problem with arbitrary spin
del Sol Mesa, Antonio

in Foundations of Physics (1997)

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1996

See detailThe dirac oscillator of arbitrary spin
del Sol Mesa, Antonio

in Journal of Physics : A Mathematical & General (1996)

See detailFermionic anomalies in quantum-mechanical relativistic problems
del Sol Mesa, Antonio

in Il Nuovo Cimento della Societa Italiana di Fisica. C (1996)

See detailOn some solutions of the Dirac equation
del Sol Mesa, Antonio

in Journal of Physics : A Mathematical & General (1996)

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1995

See detailSymmetry Lie algebra of the two body systems with a Dirac oscillator interaction
del Sol Mesa, Antonio

in Revista Mexicana de Física (1995)

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1994

See detailOn some aspects of a relativistic problem
del Sol Mesa, Antonio

in Canadian Journal of Physics (1994)

See detailRelationship between different approaches to the relativistic two body problem
del Sol Mesa, Antonio

in Journal of Physics : A Mathematical & General (1994)

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1993

See detailQuantum groups and the recovery of the U(3) symmetry in the hamiltonian of the nuclear shell model
del Sol Mesa, Antonio

in Journal of Physics : A Mathematical & General (1993)

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1992

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