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Javier Jarazo

Javier Jarazo
Postal Address Université du Luxembourg
2, Avenue de l'Université
L-4365 Esch-sur-Alzette

Postdoc in the Developmental & Cellular Biology group (Schwamborn Lab)

Last updated on: Monday, 04 June 2018

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2021

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See detailPINK1 deficiency impairs adult neurogenesis of dopaminergic neurons
Brown, Sarah J; Boussaad, Ibrahim; Jarazo, Javier; Fitzgerald, Julia C; Antony, Paul; Keatinge, Marcus; Blechman, Janna; Schwamborn, Jens Christian; Krüger, Rejko; Placzek, Marysia; Bandmann, Oliver

in Scientific Reports (2021)

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2020

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See detailImpaired Mitochondrial-Endoplasmic Reticulum Interaction and Mitophagy in Miro1-Mutant Neurons in Parkinson’s Disease
Berenguer-Escuder, Clara; Grossmann, Dajana; Antony, Paul; Arena, Giuseppe; Wasner, Kobi; Massart, François; Jarazo, Javier; Walter, Jonas; Schwamborn, Jens Christian; Grünewald, Anne; Krüger, Rejko

in Human Molecular Genetics (2020)

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See detailSynapse alterations precede neuronal damage and storage pathology in a human cerebral organoid model of CLN3-juvenile neuronal ceroid lipofuscinosis
Gomez Giro, Gemma; Arias-Fuenzalida, Jonathan; Jarazo, Javier; Zeuschner, Dagmar; Ali, Muhammad; Possemis, Nina; Bolognin, Silvia; Halder, Rashi; Jäger, Christian; Kuper, Willemijn; van Hasselt, Peter; Zaehres, Holm; del Sol Mesa, Antonio; van der Putten, Herman; Schoeler, Hans; Schwamborn, Jens Christian

in Acta Neuropathologica Communications (2020)

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See detailMitochondrial and Clearance Impairment in p.D620N VPS35 Patient-Derived Neurons
Hanss, Zoé; Larsen, Simone; Antony, Paul; Mencke, Pauline; Massart, François; Jarazo, Javier; Schwamborn, Jens Christian; Barbuti, Peter; Mellick, George; Krüger, Rejko

in Movement Disorders (2020)

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See detailPassive controlled flow for Parkinson’s disease neuronal cell culture in 3D microfluidic devices
Kane, Khalid; Jarazo, Javier; Lucumi Moreno, Edinson; Fleming, Ronan; Schwamborn, Jens Christian

in Organs-on-a-Chip (2020)

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2019

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See detailAutomated high-throughput high-content autophagy and mitophagy analysis platform
Arias, Jonathan; Jarazo, Javier; Walter, Jonas; Gomez Giro, Gemma; Forster, Julia; Antony, Paul; Krüger, Rejko; Schwamborn, Jens Christian

in Scientific Reports (2019)

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See detailFrom tech to bench: Deep Learning pipeline for image segmentation of high-throughput high-content microscopy data
Garcia Santa Cruz, Beatriz; Jarazo, Javier; Saraiva, Claudia; Gomez Giro, Gemma; Modamio Chamarro, Jennifer; Sabaté Soler, Sonia; Kyriaki, Barmpa; Antony, Paul; Schwamborn, Jens Christian; Hertel, Frank; Husch, Andreas

Poster (2019, November 29)

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See detailDeep Learning Quality Control for High-Throughput High-Content Screening Microscopy Images
Garcia Santa Cruz, Beatriz; Jarazo, Javier; Schwamborn, Jens Christian; Hertel, Frank; Husch, Andreas

Poster (2019, October 10)

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See detailQuality Control Strategy for CRISPRCas9- based Gene Editing Complicated by a Pseudogene
Hanss, Zoé; Boussaad, Ibrahim; Jarazo, Javier; Schwamborn, Jens Christian; Krüger, Rejko

in Frontiers in Genetics (2019)

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See detailGuidelines for Fluorescent Guided Biallelic HDR Targeting Selection With PiggyBac System Removal for Gene Editing
Jarazo, Javier; Qing, Xiaobing; Schwamborn, Jens Christian

in Frontiers in Genetics (2019)

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See detailAutomated microfluidic cell culture of stem cell derived dopaminergic neurons
Kane, Khalid; Lucumi Moreno, Edinson; Hachi, Siham; Walter, Moriz; Jarazo, Javier; Oliveira, Miguel; Hankemeier, Thomas; Vulto, Paul; Schwamborn, Jens Christian; Thoma, Martin; Fleming, Ronan

in Scientific Reports (2019)

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See detailImpaired serine metabolism complements LRRK2-G2019S pathogenicity in PD patients
Nickels, Sarah; Walter, Jonas; Bolognin, Silvia; Gerard, Deborah; Jäger, Christian; Qing, Xiaobing; Tisserand, Johan; Jarazo, Javier; Hemmer, Kathrin; Harms, Amy; Halder, Rashi; Lucarelli, Philippe; Berger, Emanuel; Antony, Paul; Glaab, Enrico; Hankemeier, Thomas; Klein, Christine; Sauter, Thomas; Sinkkonen, Lasse; Schwamborn, Jens Christian

in Parkinsonism and Related Disorders (2019)

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See detailNeural Stem Cells of Parkinson's Disease Patients Exhibit Aberrant Mitochondrial Morphology and Functionality
Walter, Jonas; Bolognin, Silvia; Antony, Paul; Nickels, Sarah; Poovathhingal, Suresh; Salamanca, Luis; Magni, Stefano; Perfeito, Rita; Hoel, Fredrik; Qing, Xiaobing; Jarazo, Javier; Arias-Fuenzalida, Jonathan; Ignac, Tomasz; Monzel, Anna Sophia; Gonzalez-Cano, Laura; Pereira de Almeida, Luis; Skupin, Alexander; Tronstad, Karl; Schwamborn, Jens Christian

in Stem Cell Reports (2019)

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2018

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See detail3D Cultures of Parkinson's Disease‐Specific Dopaminergic Neurons for High Content Phenotyping and Drug Testing
Bolognin, Silvia; Fossépré, Marie; Qing, Xiaobing; Jarazo, Javier; Ščančar, Janez; Lucumi Moreno, Edinson; Nickels, Sarah; Wasner, Kobi; Ouzren, Nassima; Walter, Jonas; Grünewald, Anne; Glaab, Enrico; Salamanca, Luis; Fleming, Ronan M. T.; Antony, Paul; Schwamborn, Jens Christian

in Advanced Science (2018)

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2017

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See detailFACS-Assisted CRISPR-Cas9 Genome Editing Facilitates Parkinson's Disease Modeling
Arias, Jonathan; Jarazo, Javier; Qing, Xiaobing; Walter, Jonas; Gomez Giro, Gemma; Nickels, Sarah; Zaehres, Holm; Schoeler, Hans Robert; Schwamborn, Jens Christian

in Stem Cell Reports (2017)

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See detailAutomated micro uidic cell culture of stem cell derived dopaminergic neurons in Parkinson's disease
Kane, Khalid; Lucumi Moreno, Edinson; Hachi, Siham; Walter, Moriz; Jarazo, Javier; Hankemeier, Thomas; Vulto, Paul; Schwamborn, Jens Christian; Thoma, Martin; Fleming, Ronan MT

in bioRxiv (2017)

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See detailDerivation of Human Midbrain-Specific Organoids from Neuroepithelial Stem Cells
Monzel, Anna Sophia; Smits, Lisa; Hemmer, Kathrin; Hachi, Siham; Lucumi Moreno, Edinson; Van Wüllen, Thea Maria; Jarazo, Javier; Walter, Jonas; Werthschulte, Inga; Boussaad, Ibrahim; Berger, Emanuel; Fleming, Ronan MT; Bolognin, Silvia; Schwamborn, Jens Christian

in Stem Cell Reports (2017)

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See detailCRISPR/Cas9 and piggyBac-mediated footprint-free LRRK2-G2019S knock-in reveals neuronal complexity phenotypes and α-Synuclein modulation in dopaminergic neurons
Qing, Xiaobing; Walter, Jonas; Jarazo, Javier; Arias, Jonathan; Hillje, Anna-Lena; Schwamborn, Jens Christian

in Stem Cell Research (2017)

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