Home // LCSB // People // Patrick May

Patrick May

Research scientist

Faculty or Centre Luxembourg Centre for Systems Biomedicine
Postal Address Université du Luxembourg
6, avenue du Swing
L-4367 Belvaux
Campus Office BioTech II Ketterthill, 4.03
Email
Telephone (+352) 46 66 44 6263

Senior Resercher in the Bioinformatics Core group (R. Schneider Lab)

Last updated on: Tuesday, 01 December 2015

powered by
orbilu.uni.lu


Articles published in scientific periodicals

Full Text
See detailGuideline-based and bioinformatic reassessment of lesion-associated gene and variant pathogenicity in focal human epilepsies
Niestroj, Lisa-Marie; Du, Juanjiangmeng; Nothnagel, Michael; May, Patrick; Palotie, Aarno; Daly, Mark J.; Nürnberg, Peter; Blümcke, Ingmar; Lal, Dennis

in Epilepsia (2018)

Full Text
See detailMajor changes of cell function and toxicant sensitivity in cultured cells undergoing mild, quasi-natural genetic drift
Gutbier, Simon; May, Patrick; Berthelot, Sylvie; Krishna, Abhimanyu; Trefzer, Timo; Behbehani, Mehri; Effremova, Liudmilla; Delp, Johannes; Gstraunthaler, Gerhard; Waldmann, Tanja; Leist, Marcel

in Archives of Toxicology (2018)

Full Text
See detailRare gene deletions in genetic generalized and Rolandic epilepsies
Jabbari, Kamel; Bobbili, Dheeraj Reddy; Lal, Dennis; Reinthaler, Eva M.; Schubert, Julian; Wolking, Stefan; Sinha, Vishai; Motameny, Susanne; Thiele, Holger; Kawalla, Amit; Altmüller, Janine; Toliat, Mohammed Reza; Kraaij, Robert; van Rooij, Jeroen; Uitterlinden, André G.; Ikram, M. Arfam; EuroEPINOMICS CoGIE Consortium; Balling, Rudi; Zara, Federico; Lehesjoki, Anna-Elina; Krause, Roland; Zimprich, Fritz; Sander, Thomas; Neubauer, Bernd A.; May, Patrick; Lerche, Holger; Nürnberg, Peter

in PLoS ONE (2018)

Full Text
See detailRare coding variants in genes encoding GABAA receptors in genetic generalised epilepsies: an exome-based case-control study
May, Patrick; Girard, Simon; Harrer, Merle; Bobbili, Dheeraj Reddy; Schubert, Julian; Wolking, Stefan; Becker, Felicitas; Lachance-Touchette, Pamela; Meloche, Caroline; Gravel, Micheline; Niturad, Christina E.; Knaus, Julia; De Kovel, Carolien; Toliat, Mohamad; Polvi, Anne; Iacomino, Michele; Guerrero-López, Rosa; Baulac, Stéphanie; Marini, Carla; Thiele, Holger; Altmüller, Janine; Jabbari, Kamel; Ruppert, Ann-Kathrin; Jurkowski, Wiktor; Lal, Dennis; Rusconi, Raffaella; Cestèle, Sandrine; Terragni, Benedetta; Coombs, Ian D.; Reid, Christopher A.; Striano, Pasquale; Caglayan, Hande; Siren, Auli; Everett, Kate; Møller, Rikke S.; Hjalgrim, Hille; Muhle, Hiltrud; Helbig, Ingo; Kunz, Wolfram S.; Weber, Yvonne G.; De Jonghe, Peter; Sisodiya, Sanjay M.; Nabbout, Rima; Franceschetti, Silvana; Coppola, Antonietta; Vari, Maria S.; Kasteleijn-Nolst Trenité, Dorothée; Baykan, Betul; Ozbek, Ugur; Bebek, Nerses; Klein, Karl M.; Rosenow, Felix; Nguyen, Dang K.; Dubeau, Francis; Carmant, Lionel; Lortie, Anne; Desbiens, Richard; Clément, Jean-François; Cieuta-Walti; Sills, Graeme J.; Auce, Pauls; Francin, Ben; Johnson, Michael R.; Berghuis, Bianca; Sander, Josemir W.; Avbersek, Andreja; McCormack, Mark; Cavalleri, Gianpiero L.; Delanty, Norman; Depondt, Chantal; Krenn, Martin; Zimprich, Fritz; Peter, Sarah; Nikanorova, Marina; Kraaij, Robert; van Rooij, Jeroen; Balling, Rudi; Ikram, M. Arfan; Uitterlinden, André G.; Avanzini, Giuliano; Schorge, Stephanie; Petrou, Steven; Mantegazza, Massimo; Sander, Thomas; LeGuern, Eric; Serratosa Jose M.; Koeleman, Bobby P.C.; Palotie, Aarno; Lehesjoki, Anna-Elina; Nothnagel, Michael; Nürnberg, Peter; Maljevic, Snezana; Zara, Federico; Cossette, Patrick; Krause, Roland; Lerche, Holger

in Lancet Neurology (2018), 17(8), 699-708

Full Text
See detailThe RNA Complement of Outer Membrane Vesicles From Salmonella enterica Serovar Typhimurium Under Distinct Culture Conditions
Malabirade, Antoine; Habier, Janine; Heintz-Buschart, Anna; May, Patrick; Godet, Julien; Halder, Rashi; Etheridge, Alton; Galas, David; Wilmes, Paul; Fritz, Joëlle

in Frontiers in Microbiology (2018), 9

Full Text
See detailA rare loss-of function variant of ADAM17 is associated with late-onset familial Alzheimer disease
Hartl, Daniela; May, Patrick; Gu, Wei; Mayhaus, Manuel; Pichler, Sabrina; Spaniol, Christian; Glaab, Enrico; Bobbili, Dheeraj Reddy; Antony, Paul; Köglsberger, Sandra; Kurz, Alexander; Grimmer, Timo; Morgan, Kevin; Vardarajan, Badri N.; Reitz, Christiane; Hardy, John; Bras, Jose; Guerreiro, Rita; AESG; Balling, Rudi; Schneider, Jochen; Riemenschneider, Matthias

in Molecular Psychiatry (2018)

Full Text
See detailDe novo Variants in Neurodevelopmental Disorders with Epilepsy
Heyne, Henrike O.; Singh, Tarijinder; Stamberger, Hannah; Jamra, Rami Abou; Caglayan, Hande; Craiu, Dana; De Jonghe, Peter; Guerrini, Renzo; Helbig, Katherine L.; Koeleman, Bobby P.C.; Kosmicki, Jack A.; Linnankivi, Tarja; May, Patrick; Muhle, Hiltrud; Møller, Rikke S.; Neubauer, Bernd A.; Palotie, Aarno; Pendziwiat, Manuela; Striano, Pasquale; Tang, Sha; Wu, Sitao; EUROEPINOMICS RES Consortium; Poduri, Annapurna; Weber, Yvonne G.; Weckhuysen, Sarah; Sisodiya, Sanjay M.; Daly, Mark; Helbig, Ingo; Lal, Dennis; Lemke, Johannes R.

in Nature Genetics (2018)

Full Text
See detailSmall RNA profiling of low biomass samples: identification and removal of contaminants
Heintz-Buschart, Anna; Yusuf, Dilmurat; Kaysen, Anne; Etheridge, Alton; Fritz, Joëlle; May, Patrick; de Beaufort, Carine; Upadhyaya, Bimal Babu; Ghosal, Anubrata; Galas, David J; Wilmes, Paul

in BMC Biology (2018), 16(52),

Full Text
See detailRare ABCA7 variants in 2 German families with Alzheimer disease
May, Patrick; Pichler, Sabrina; Hartl, Daniela; Bobbili, Dheeraj Reddy; Mayhaus, Manuel; Spaniol, Christian; Kurz, Alexander; Balling, Rudi; Schneider, Jochen; Riemenschneider, Matthias

in Neurology Genetics (2018), 4(2),

Full Text
See detailNatural variation of chronological aging in the Saccharomyces cerevisiae species reveals diet-dependent mechanisms of life span control
Jung, Paul; Zhang, Zhi; Paczia, Nicole; Jäger, Christian; Ignac, Tomasz; May, Patrick; Linster, Carole

in npj Aging and Mechanisms of Disease (2018), 4(3),

Full Text
See detailReply: No evidence for rare TRAP1 mutations influencing the risk of idiopathic Parkinson’s disease
Fitzgerald, Julia C.; Zimprich, Alexander; Bobbili, Dheeraj Reddy; Sharma, Manu; May, Patrick; Krüger, Rejko

in Brain : A Journal of Neurology (2018)

Full Text
See detailExome-wide analysis of mutational burden in patients with typical and atypical Rolandic Epilepsy
Bobbili, Dheeraj Reddy; Lal, Dennis; May, Patrick; Reinthaler, Eva M.; Jabbari, Kamel; Thiele, Holger; Nothnagel, Michael; Jurkowski, Wiktor; EuroEPINOMICS COGIE Consortium; Balling, Rudi; Feucht, Martha; Nürnberg, Peter; Lerche, Holger; Zimprich, Fritz; Krause, Roland; Neubauer, Bernd A.

in European Journal of Human Genetics (2018)

See detailClinical spectrum of STX1B-related epileptic disorders
Wolking, Stefan; May, Patrick; Mei, Davide; Møller, Rikke S.; Balestrini, Simona; Helbig, Katherine L.; Altuzurra, Cecilia D.; Chatron, Nicolas; Kaiwar, Charu; Stoehr, Kathrin; Widdess-Walsh, Peter; Mendelsohn, Bryce A.; Numis, Adam; Cilio, Maria R.; Van Paesschen, Wim; Svendsen, Lene L.; Oates, Stephanie; Hughes, Elaine; Goyal, Sushma; Brown, Kathleen; Saenz, Margarita S.; Dorn, Thomas; Muhle, Hiltrud; Pagnamenta, Alistair T.; Vavoulis, Dimitris V.; Knight, Samantha J.L.; Taylor, Jenny C.; Canevini, Maria P.; Darra, Franchesca; Gavrilova, Ralitza; Powis, Zöe; Tang, Shan; Marquetand, Justus; Armstrong, Martin; McHale, Duncan; Klee, Ernst W.; Kluger, Gerhard J.; Lowenstein, Daniel H.; Weckhuysen, Sarah; Pal, Deb K.; Helbig, Ingo; Guerrini, Renzo; Thomas, Rhys H.; Rees, Mark I.; Lesca, Gaetan; Sisodiya, Sanjay M.; Weber, Yvonne G.; Lal, Dennis; Marini, Carla; Lerche, Holger; Schubert, Julian

in Neurology (2018)

Full Text
See detailConfronting the catalytic dark matter encoded by sequenced genomes
Ellens, Kenneth W.; Christian, Nils; Satagopam, Venkata; May, Patrick; Linster, Carole

in Nucleic Acids Research (2017), 45(20), 11495-11514

Full Text
See detailRare GABRA3 variants are associated with epileptic seizures, encephalopathy and dysmorphic features
Niturad, Elena Christina; Lev, Dorit; Kalscheuer, Vera M; Charzewska, Agnieszka; Schubert, Julian; Lerman-Sagie, Tally; Kroes, Hester Y; Oegema, Renske; Traverso, Monica; Specchio, Nicola; Lassota, Maria; Chelly, Jamel; Bennett-Back, Odeya; Carmi, Nirit; Koffler-Brill, Tal; Iacomino, Michele; Trivisano, Marina; Capovilla, Giuseppe; Striano, Pasquale; Nawara, Magdalena; Rzonca, Sylwia; Fischer, Ute; Bienek, Melanie; Jensen, Corinna; Hu, Hao; Thiele, Holger; Altmüller, Janine; Krause, Roland; May, Patrick; Becker, Felicitas; EuroEPINOMICS Consortium; Balling, Rudi; Biskup, Saskia; Haas, Stefan A; Nürnberg, Peter; van Gassen, Koen L I; Lerche, Holger; Zara, Federico; Maljevic, Snezana; Leshinsky-Silver, Esther

in Brain : A Journal of Neurology (2017), 140(11), 2879-2894

Full Text
See detailAlterations in the α2δ ligand, thrombospondin-1, in a rat model of spontaneous absence epilepsy and in patients with idiopathic/genetic generalized epilepsies
Santolini, Ines; Celli, Roberta; Cannella, Milena; Imbriglio, Tiziana; Guiducci, Michela; Parisi, Pasquale; Schubert, Julian; Iacomino, Michele; Zara, Federico; Lerche, Holger; EuroEPINOMICS CoGIE Consortium; May, Patrick; Krause, Roland; Balling, Rudi; Genetic Commission of Italian League Against Epilepsy (LICE); Moyanova, Slavianka; Ngomba, Richard Teke; van Luijtellar, Gilles; Battaglia, Giuseppe; Bruno, Valeria; Striano, Pasquale; Nicoletti, Ferdinando

in Epilepsia (2017)

Full Text
See detailMetformin reverses TRAP1 mutation-associated alterations in mitochondrial function in Parkinson's disease
Fitzgerald, Julia C.; Zimprich, Alexander; Carvajal-Berrio, Daniel A.; Schindler, Kevin M.; Maurer, Brigitte; Schulte, Claudia; Bus, Christine; Hauser, Anne-Kathrin; Kübler, Manuela; Lewin, Rahel; Bobbili, Dheeraj Reddy; Schwarz, Lisa M.; Vartholomaiou, Evangela; Brockmann, Kathrin; Wüst, Richard; Madlung, Johannes; Nordheim, Alfred; Riess, Olaf; Martins, L. Miguel; Glaab, Enrico; May, Patrick; Schenke-Layland, Katja; Picard, Didier; Sharma, Manu; Gasser, Thomas; Krüger, Rejko

in Brain : A Journal of Neurology (2017), 140(9), 2444-2459

Full Text
See detailApplication of rare variant transmission disequilibrium tests to epileptic encephalopathy trio sequence data
Allen, Andrew S.; Berkovic, Samuel F.; Bridgers, Joshua; Cossette, Patrick; Dlugos, Dennis; Epstein, Michael P.; Glauser, Tracy; Goldstein, David B.; Heinzen, Erin L.; Jiang, Yu; Johnson, Michael R.; Kuzniecky, Ruben; Lowenstein, Daniel H.; Marson, Anthony G.; Mefford, Heather C.; O'Brien, Terence J.; Ottman, Ruth; Petrou, Steven; Petrovski, Slavé; Poduri, Annapurna; Ren, Zhong; Scheffer, Ingrid E.; Sherr, Elliott; Wang, Quanli; Balling, Rudi; Barisic, Nina; Baulac, Stéphanie; Caglayan, Hande; Craiu, Dana; De Jonghe, Peter; Depienne, Christel; Guerrini, Renzo; Helbig, Ingo; Hjalgrim, Helle; Hoffman-Zacharska, Dorota; Jähn, Johanna; Klein, Karl Martin; Koeleman, Bobby; Komarek, Vladimir; Krause, Roland; Leguern, Eric; Lehesjoki, Anna-Elina; Lemke, Johannes R.; Lerche, Holger; Linnankivi, Tarja; Marini, Carla; May, Patrick; Møller, Rikke S.; Muhle, Hiltrud; Pal, Deb; Palotie, Aarno; Rosenow, Felix; Selmer, Kaja; Serratosa, Jose M.; Sisodiya, Sanjay; Stephani, Ulrich; Sterbova, Katalin; Striano, Pasquale; Suls, Arvid; Talvik, Tiina; von Spiczak, Sarah; Weber, Yvonne; Weckhuysen, Sarah; Zara, Federico; Abou-Khalil, Bassel; Alldredge, Brian K.; Amrom, Dina; Andermann, Eva; Andermann, Frederick; Bautista, Jocelyn F.; Berkovic, Samuel F.; Bluvstein, Judith; Cascino, Gregory D.; Consalvo, Damian; Crumrine, Patricia; Devinsky, Orrin; Dlugos, Dennis; Epstein, Michael P.; Fiol, Miguel E.; Fountain, Nathan B.; French, Jacqueline; Friedman, Daniel; Glauser, Tracy; Haas, Kevin; Haut, Sheryl R.; Hayward, Jean; Joshi, Sucheta; Kanner, Andres; Kirsch, Heidi E.; Kossoff, Eric H.; Kuperman, Rachel; Kuzniecky, Ruben; Lowenstein, Daniel H.; McGuire, Shannon M.; Motika, Paul V.; Novotny, Edward J.; Ottman, Ruth; Paolicchi, Juliann M.; Parent, Jack; Park, Kristen; Poduri, Annapurna; Scheffer, Ingrid E.; Shellhaas, Renée A.; Sherr, Elliott; Sirven, Joseph; Smith, Michael C.; Sullivan, Joseph; Thio, Liu Lin; Venkat, Anu; Vining, Eileen P. G.; Von Allmen, Gretchen K.; Weisenberg, Judith L.; Widdess-Walsh, Peter; Winawer, Melodie R.

in European Journal of Human Genetics (2017)

Full Text
See detailNeuroChip, an updated version of the NeuroX genotyping platform to rapidly screen for variants associated with neurological diseases
Blauwendraat, Cornelis; Faghri, Faraz; Pihlstrom, Lasse; Geiger, Joshua T.; Elbaz, Alexis; Lesage, Susanne; May, Patrick; Aude, Nicolas; Abramzon, Yevgeniya; Murphy, Natalie A.; Gibbs, J. Raphael; Ryten, Mina; Ferrari, Raffaele; Bras, Jose; Guerreiro, Rita; Williams, Julie; Sims, Rebecca; Lubbe, Steven; Hernandez, Dena G.; Mok, Kin Y.; Robak, Laurie; Camphell, Roy H.; Rogaeva, Ekaterina; Traynor, Bryan J.; Chia, Ruth; Chung, Sun Ju; International Parkinson’s Disease Genomics Consortium (IPDGC); COURAGE-PD Consortium; Glaab, Enrico; Balling, Rudi; Hardy, John A.; Brice, Alexis; Houlden, Henry; Shulman, Joshua M.; Morris, Huw R.; Gasser, Thomas; Heutink, Peter; Krüger, Rejko; Sharma, Manu; Simon-Sanchez, Javier; Nalls, Mike A.; Singleton, Andrew B.; Scholz, Sonja W.

in Neurobiology of Aging (2017)

Full Text
See detailBiallelic Variants in OTUD6B Cause an Intellectual Disability Syndrome Associated with Seizures and Dysmorphic Features
Santiago-Sim, Teresa; Burrage, Lindsay C.; Ebstein, Frederic; Tokita, Mary J.; Miller, Marcus; Bi, Weimin; Braxton, Alicia A.; Rosenfeld, Jill A.; Shahrour, Maher; Lehmann, Andrea; Cogne, Benjamin; Küry, Sebastien; Besnard, Thomas; Isidor, Bertrand; Bézieau, Stephane; Hazert, Isabelle; Nagakura, Honey; Immken, LaDonna L.; Littlejohn, Rebecca O.; Roeder, Elizabeth; Euroepinomics Res Consortium ARE working group; Balling, Rudi; Caglayan, Hande; Kara, Bulent; Hardies, Katia; Weckhuysen, Sarah; May, Patrick; Lemke, Johannes R.; Elpeleg, Orly; Abu-Libdeh, Bassam; James, Kiely N.; Slihavy, Jennifer L.; Issa, Mahmoud Y.; Zaki, Maha S.; Gleeson, Joseph G.; Seavitt, John R.; Dickinson, Mary E.; Ljungberg, M. Cecilia; Wells, Sara; Johnson, Sara L.; Teboul, Lydia; Eng, Christine M.; Yang, Yaping; Kloetzel, Peter-Michael; Heaney, Jason D.; Walkiewicz, Magdalena A.

in American Journal of Human Genetics (2017), 100(4), 676-688

Full Text
See detailRecessive mutations in SLC35A3 cause early onset epileptic encephalopathy with skeletal defects
Marini, Carla; Hardies, Katia; Pisano, Tiziana; May, Patrick; Weckhuysen, Sarah; Cellini, Elena; Suls, Arvid; Mei, Davide; Balling, Rudi; De Jonghe, Peter; Helbig, Ingo; Garozzo, Domenico; EuroEPINOMICS consortium AR working group; Guerrini, Renzo

in American Journal of Medical Genetics. Part A (2017), 173(4), 1119-1123

Full Text
See detailDe Novo Mutations in Synaptic Transmission Genes Including DNM1 Cause Epileptic Encephalopathies.
Appenzeller, Silke; Balling, Rudi; Barisic, Nina; Baulac, Stéphanie; Caglayan, Hande; Craiu, Dana; Jonghe, Peter De; Depienne, Christel; Dimova, Petia; Djémié, Tania; Gormley, Padhraig; Guerrini, Renzo; Helbig, Ingo; Hjalgrim, Helle; Hoffman-Zacharska, Dorota; Jähn, Johanna; Klein, Karl Martin; Koeleman, Bobby; Komarek, Vladimir; Krause, Roland; Kuhlenbäumer, Gregor; Leguern, Eric; Lehesjoki, Anna-Elina; Lemke, Johannes R.; Lerche, Holger; Linnankivi, Tarja; Marini, Carla; May, Patrick; Møller, Rikke S.; Muhle, Hiltrud; Pal, Deb; Palotie, Aarno; Pendziwiat, Manuela; Robbiano, Angela; Roelens, Filip; Rosenow, Felix; Selmer, Kaja; Serratosa, Jose M.; Sisodiya, Sanjay; Stephani, Ulrich; Sterbova, Katalin; Striano, Pasquale; Suls, Arvid; Talvik, Tiina; Spiczak, Sarah Von; Weber, Yvonne; Weckhuysen, Sarah; Zara, Federico; Abou-Khalil, Bassel; Alldredge, Brian K.; Andermann, Eva; Andermann, Frederick; Amrom, Dina; Bautista, Jocelyn F.; Berkovic, Samuel F.; Bluvstein, Judith; Boro, Alex; Cascino, Gregory; Consalvo, Damian; Crumrine, Patricia; Devinsky, Orrin; Dlugos, Dennis; Epstein, Michael P.; Fiol, Miguel; Fountain, Nathan B.; French, Jacqueline; Friedman, Daniel; Geller, Eric B.; Glauser, Tracy; Glynn, Simon; Haas, Kevin; Haut, Sheryl R.; Hayward, Jean; Helmers, Sandra L.; Joshi, Sucheta; Kanner, Andres; Kirsch, Heidi E.; Knowlton, Robert C.; Kossoff, Eric H.; Kuperman, Rachel; Kuzniecky, Ruben; Lowenstein, Daniel H.; McGuire, Shannon M.; Motika, Paul V.; Novotny, Edward J.; Ottman, Ruth; Paolicchi, Juliann M.; Parent, Jack; Park, Kristen; Poduri, Annapurna; Sadleir, Lynette; Scheffer, Ingrid E.; Shellhaas, Renée A.; Sherr, Elliott; Shih, Jerry J.; Singh, Rani; Sirven, Joseph; Smith, Michael C.; Sullivan, Joe; Thio, Liu Lin; Venkat, Anu; Vining, Eileen P. G.; Allmen, Gretchen K. Von; Weisenberg, Judith L.; Widdess-Walsh, Peter; Winawer, Melodie R.; Allen, Andrew S.; Berkovic, Samuel F.; Cossette, Patrick; Delanty, Norman; Dlugos, Dennis; Eichler, Evan E.; Epstein, Michael P.; Glauser, Tracy; Goldstein, David B.; Han, Yujun; Heinzen, Erin L.; Johnson, Michael R.; Kuzniecky, Ruben; Lowenstein, Daniel H.; Marson, Anthony G.; Mefford, Heather C.; Nieh, Sahar Esmaeeli; O’Brien, Terence J.; Ottman, Ruth; Petrou, Stephen; Petrovski, Slavé; Poduri, Annapurna; Ruzzo, Elizabeth K.; Scheffer, Ingrid E.; Sherr, Elliott

in American Journal of Human Genetics (2017), 100(1), 179-

Full Text
See detailIMP: a pipeline for reproducible referenceindependent integrated metagenomic and metatranscriptomic analyses
Narayanasamy, Shaman; Jarosz, Yohan; Muller, Emilie; Buschart, Anna; Herold, Malte; Kaysen, Anne; Laczny, Cédric; Pinel, Nicolás; May, Patrick; Wilmes, Paul

in Genome Biology (2016), 17

Full Text
See detailTargeted sequencing of 351 candidate genes for epileptic encephalopathy in a large cohort of patients
de Kovel, Carolien G.F.; Brilstra, Eva H.; van Kempen J.A.; van't Slot, Ruben; Nijman, Isaac J.; Afawi, Zaid; De Jonghe, Peter; Djemie, Tania; Guerrini, Renzo; Hardies, Katia; Helbig, Ingo; Hendrickx, Rik; Kanaan, Moine; Kramer, Uri; Lehesjoki, Anna-Elina E.; Lemke, Johannes R.; Marini, Carla; Mei, Davide; Moller, Rikke S.; Pendziwiat, Manuela; Stamberger, Hannah; Suls, Arvid; Weckhuysen, Sarah; EuroEPINOMICS RES Consortium; May, Patrick; Balling, Rudi; Koeleman, Bobby P.C.

in Molecular Genetics & Genomic Medicine (2016), 4(5), 568-80

Full Text
See detailLoss of SYNJ1 dual phosphatase activity leads to early onset refractory seizures and progressive neurological decline
Hardies, Katia; Cai, Yiying; Jardel, Claude; Jansen, Anna C.; Cao, Mian; May, Patrick; Djémié, Tania; Hachon Le Camus, Caroline; Keymolen, Kathelijn; Deconinck, Tine; Bhambhani, Vikas; Long, Catherine; Sajan, Samin A.; Helbig, Katherine L.; Suls, Arvid; Balling, Rudi; Helbig, Ingo; De Jonghe, Peter; Depienne, Christel; De Camilli, Pietro; Weckhuysen, Sarah

in Brain : A Journal of Neurology (2016)

Full Text
See detailEvaluation of Presumably Disease Causing SCN1A Variants in a Cohort of Common Epilepsy Syndromes
Lal, Dennis; Reinthaler, Eva; Dejanovic; May, Patrick; Thiele, Holger; Lehesjoki, Anna-Elina; Schwarz, Guenter; Riesch, Erik; Ikram, Arfan; van Duijn, Cornelia; Uitterlinden, Andre; Steinböck, Hannelore; Gruber-Sedlmayr, Ursula; Neophytou, Birgit; Zara, Frederico; Hahn, Andreas; Genetic Commission of the Italian League against Epilepsy; EuroEPINOMICS CoGIE Consortium; Balling, Rudi; Becker, Felicitas; Weber, Yvonne; Cilio, Maria Roberta; Kunz, Wolfram; Krause, Roland; Zimprich, Fritz; Lemke, Johannes R.; Nürnberg, Peter; Sander, Thomas; Lerche, Holger; Neubauer, Bernd

in PLoS ONE (2016)

Full Text
See detailThe new Protein Topology Graph Library web server
Schäfer, Tim; Bruneß, Daniel; Scheck, Andreas; May, Patrick; Koch, Ina

in Bioinformatics (2016), 32(3), 474-6

Full Text
See detailErratum: Integrated multi-omics of the human gut microbiome in a case study of familial type 1 diabetes.
Heintz-Buschart, Anna; May, Patrick; Laczny, Cedric C.; Lebrun, Laura; Bellora, Camille; Krishna, Abhimanyu; Wampach, Linda; Schneider, Jochen; Hogan, Angela; Beaufort, Carine De; Wilmes, Paul

in Nature microbiology (2016), 2

Full Text
See detailIntegrated multi-omics of the human gut microbiome in a case study of familial type 1 diabetes.
Heintz-Buschart, Anna; May, Patrick; Laczny, Cedric C.; Lebrun, Laura; Bellora, Camille; Krishna, Abhimanyu; Wampach, Linda; Schneider, Jochen; Hogan, Angela; de Beaufort, Carine; Wilmes, Paul

in Nature microbiology (2016), 2

Full Text
See detailIdentification, recovery, and refinement of hitherto undescribed population-level genomes from the human gastrointestinal tract
Laczny, Cedric C.; Muller, Emilie; Heintz-Buschart, Anna; Herold, Malte; Lebrun, Laura; Hogan, Angela; May, Patrick; de Beaufort, Carine; Wilmes, Paul

in Frontiers in Microbiology (2016), 7(884),

Full Text
See detailA novel Fanconi anemia subtype associated with a dominant-negative mutation in RAD51
Ameziane, Najim; May, Patrick; Van de Vrugt, Henri J.; Van Rossum-Fikkert, Sari E.; Ristic, Dejan; Williams, Gareth J.; Balk, Jesper; Rockx, Davy; Li, Hong; Rooimans, Martin A.; Oostra, Anneke B.; Velleuer, Eunike; Dietrich, Ralf; Bleijerveld, Onno B.; Altelaar, A.F. Maarten; Meijers-Heijboer, Hanne; Joenje, Hans; Glusman, Gustavo; Roach, Jared C.; Hood, Leroy; Galas, David J.; Balling, Rudi; den Dunnen, Johan; De Winter, Johan P.; Kanaar, Roland; Gelinas, Richard; Dorsman, Josephine C.

in Nature Communications (2015), 6(8829),

Full Text
See detailProteomic analysis of Dhh1 complexes reveals a role for Hsp40 chaperone Ydj1 in yeast P-body assembly
Cary, Greg A.; Vinh, Dani B.H.; May, Patrick; Kuestner, Rolf; Dudley, Aimée M.

in G3 (2015)

Full Text
See detailRecessive mutations in SLC13A5 result in a loss of citrate transport and cause neonatal epilepsy, developmental delay and teeth hypoplasia
Hardies, Katia; de Kovel, Carolien G.F.; Weckhuysen, Sarah; Asselbergh, Bob; Geuens, Thomas; Deconnick, Tine; Azmi, Abdelkrim; May, Patrick; Brilstra, Eva; Becker, Felicitas; Barisic, Nina; Craiu, Dana; Braun, Kees; Lal, Dennis; Thiele, Holger; Schubert, Julian; Weber, Yvonne; van't Slot, Ruben; Autosomal recessive working group of the EuroEPINOMICS RES Consortium; Nürnberg, Peter; Balling, Rudi; Timmermann, Vincent; Lerche, Holger; Maudsley, Stuart; Helbig, Ingo; Suls, Arvid; Koeleman, Bobby P.C.; De Jonghe, Peter

in Brain : A Journal of Neurology (2015)

Full Text
See detailDe novo loss- or gain-of-function mutations in KCNA2 cause epileptic encephalopathy
Syrbe, Steffen; Hedrich, Ulrike B.S.; Riesch, Erik; Djémié, Tanja; Müller, Stephan; Møller, Rikke S.; Maher, Bridget; Hernandez-Hernandez, Laura; Synofzik, Matthis; Caglayan, Hande S.; Arslan, Mutluay; Serratosa, José M.; Nothnagel, Michael; May, Patrick; Krause, Roland; Löffler, Heidrun; Detert, Katja; Dorn, Thomas; Vogt, Heinrich; Krämer, Günter; Schöls, Ludger; Mullis, Primus E.; Linnankivi, Tarja; Lehesjoki, Anna-Elina; Sterbova, Katalin; Craiu, Dana C.; Hoffman-Zacharska, Dorota; Korff, Christian M.; Weber, Yvonne G.; Steinlin, Maja; Gallati, Sabina; Bertsche, Astrid; Bernhard, Matthias K.; Merkenschlager, Andreas; Kiess, Wieland; EUROEPINOMICS RES consortium; Balling, Rudi; Gonzalez, Michael; Züchner, Stefan; Palotie, Aarno; Suls, Arvid; De Jonghe, Peter; Helbig, Ingo; Biskup, Saskia; Wolff, Markus; Maljeviv, Snezana; Schüle, Rebecca; Sisodoya, Sanjay M.; Weckhuysen, Sarah; Lerche, Holger; Lemke, Johannes R.

in Nature Genetics (2015), 47(4), 393-9

Full Text
See detailCHD2 myoclonic encephalopathy is frequently associated with self-induced seizures
Thomas, Rhys H.; Zhang, Lin Mei; Carvill, Gemma L.; Archer, John S.; Heavin, Sinéad B.; Mandelstam, Simone A.; Craiu, Dana; Berkovic, Samuel F.; Gill, Deepak S.; Mefford, Heather C.; Scheffer, Ingrid E.; Paalotie, Aarno; Lehesjoki, Anna-Elina; Koeleman, Bobby; Marini, Carla; Depienne, Christel; Pal, Deb; Hoffman-Zacharska, Dorota; Leguern, Eric; Zara, Federico; Rosenow, Felix; Caglayan, Hande; Hjalgrim, Helle; Muhle, Hiltrud; Lerche, Holger; Helbig, Ingo; Jähn, Johanna; Lemke, Johannes; Serratosa, Jose M.; Selmer, Katja; Klein, Karl Martin; Sterbova, Katalin; Pendziwiat, Manuela; Barisic, Nina; Gormley, Padhraig; Striano, Pasquale; May, Patrick; De Jonghe, Peter; Guerrini, Renzo; Møller, Rikke S.; Krause, Roland; Balling, Rudi; Sisodiya, Sanjay; von Spiczak, Sarah; Weckhuysen, Sarah; Baulac, Stéphanie; Suls, Arvid; Djemie, Tania; Stephani, Ulrich; Komarek, Vladimir; Weber, Yvonne

in Neurology (2015), 84(9), 951-958

Full Text
See detailThe phenotypic spectrum of SCN8A encephalopathy
Larsen, Jan; Carvill, Gemma L.; Gardella, Elena; Kluger, Gerhard; Schmiedel, Gudrun; Barisic, Nina; Depienne, Christel; Brilstra, Eva; Mang, Yuan; Nielsen, Jens E.K.; Kirkpatrick, Martin; Goudie, David; Goldman, Rebecca; Jähn, Johanna A.; Jepsen, Birgit; Gill, Deepak; Döcker, Miriam; Biskup, Saskia; McMahon, Jacinta M.; Koeleman, Bobby; Harris, Mandy; Braun, Kees; de Kovel, Carolien G.F.; Marini, Carla; Specchio, Nicola; Djémié, Tania; Weckhuysen, Sarah; Krause, Roland; May, Patrick; Balling, Rudi; Tommerup, Niels; Troncoso, Monica; Troncoso, Ledia; Bevot, Andrea; Wolff, Markus; Hjalgrim, Helle; Guerrini, Renzo; Scheffer, Ingrid E.; Mefford, Heather C.; Møller, Rikke S.; EuroEPINOMICS RES Consortium CRP

in Neurology (2015), 84(5), 480-489

Full Text
See detailRecessive loss-of-function mutations in AP4S1 cause mild fever-sensitive seizures, developmental delay and spastic paraplegia through loss of AP-4 complex assembly
Hardies, Katia; May, Patrick; Djémié, Tania; Tarta-Arsene, Oana; Deconinck, Tine; Craiu, Dana; EuroEPINOMICS RES Consortium; Helbig, Ingo; Suls, Arvid; Balling, Rudi; Weckhuysen, Sarah; De Jonghe, Peter; Hirst, Jennifer

in Human Molecular Genetics (2015), 24(8), 2218-2227

Full Text
See detailComparative integrated omics: identification of key functionalities in microbial community-wide metabolic networks
Roume, Hugo; Buschart, Anna; Muller, Emilie; May, Patrick; Satagopam, Venkata; Laczny, Cédric; Narayanasamy, Shaman; Lebrun, Laura; Hoopmann, Michael; Schupp, James; Gillece, John; Hicks, Nathan; Engelthaler, David; Sauter, Thomas; Keim, Paul; Moritz, Robert; Wilmes, Paul

in Biofilms and Microbiomes (2015), 1(15007),

Full Text
See detailSystems genomics evaluation of the SH-SY5Y neuroblastoma cell line as a model for Parkinson’s disease
Krishna, Abhimanyu; Biryukov, Maria; Trefois, Christophe; Antony, Paul; Hussong, Rene; Lin, Jake; Heinäniemi, Merja; Glusman, Gustavo; Köglsberger, Sandra; Boyd, Olga; van den Berg, Bart H.J.; Linke, Dennis; Huang, David; Wang, Kai; Hood, Leroy; Tholey, Andreas; Schneider, Reinhard; Galas, David J.; Balling, Rudi; May, Patrick

in BMC Genomics (2014), 15(1154),

Full Text
See detailMutations in STX1B, encoding a presynaptic protein, cause fever-associated epilepsy syndromes
Schubert, Julian; Siekierska, Aleksandra; Langlois, Melanie; May, Patrick; Huneau, Clement; Becker, Felicitas; Muhle, Hiltrud; Suls, Arvid; Lemke, Johannes R.; de Kovel, Carolien G. F.; Thiele, Holger; Konrad, Kathryn; Kawalia, Amit; Toliat, Mohammad R.; Sander, Thomas; Ruschendorf, Franz; Caliebe, Almuth; Nagel, Inga; Kohl, Bernard; Kecskes, Angela; Jacmin, Maxime; Hardies, Katia; Weckhuysen, Sarah; Riesch, Erik; Dorn, Thomas; Brilstra, Eva H.; Baulac, Stephanie; Moller, Rikke S.; Hjalgrim, Helle; Koeleman, Bobby P. C.; EuroEPINOMICS RES Consortium; Krause, Roland; Jurkat-Rott, Karin; Lehman-Horn, Frank; Roach, Jared C.; Glusman, Gustavo; Hood, Leroy; Galas, David J.; Martin, Benoit; de Witte, Peter A. M.; Biskup, Saskia; De Jonghe, Peter; Helbig, Ingo; Balling, Rudi; Nurnberg, Peter; Crawford, Alexander Dettmar; Esguerra, Camila V.; Weber, Yvonne G.; Lerche, Holger

in Nature Genetics (2014), 46(12), 1327-32

Full Text
See detailCommunity-integrated omics links dominance of a microbial generalist to fine-tuned resource usage
Muller, Emilie; Pinel, Nicolas; Laczny, Cédric; Hoopmann, Michael; Narayanasamy, Shaman; Lebrun, Laura; Roume, Hugo; Lin, Jake; May, Patrick; Hicks, Nathan; Buschart, Anna; Wampach, Linda; Liu, Cindy; Price, Lance; Gillece, John; Guignard, Cédric; Schupp, James; Vlassis, Nikos; Baliga; Moritz, Robert; Keim, Paul; Wilmes, Paul

in Nature Communications (2014)

Full Text
See detailMolecular and Clinical Evidence for an ARMC5 Tumor Syndrome: Concurrent Inactivating Germline and Somatic Mutations are Associated with both Primary Macronodular Adrenal Hyperplasia and Meningioma
Eibelt, Ulf; Trovato, Alissa; Kloth, Michael; Gentz, Enno; Finke, Reinhard; Spranger, Joachim; Galas, David J.; Weber, Susanne; Wolf, Cristina-Alexandra; König, Katharina; Arlt, Wiebke; Büttner, Reinhard; May, Patrick; Allolio, Bruno; Schneider, Jochen

in Journal of Clinical Endocrinology and Metabolism (2014)

Full Text
See detailDe Novo Mutations in Synaptic Transmission Genes Including DNM1 Cause Epileptic Encephalopathies
Appenzeller, Silke; Balling, Rudi; Barisic, Nina; Baulac, Stephanie; Caglayan, Hande; Craiu, Dana; De Jonghe, Peter; Depienne, Christel; Dimova, Petia; Djemie, Tania; Gormly, Padhraig; Guerrini, Renzo; Helbig, Ingo; Hjalgrim, Helle; Hoffman-Zacharska, Dorota; Jähn; Klein, Karl Martin; Koeleman, Bobby; Komarek, Vladimir; Krause, Roland; Kuhlenbäumer, Gregor; Leguern, Eric; Lehesjoki, Anna-Elina; Lemke, Johannes R.; Lerche, Holger; Linnankivi, Tarja; Marini, Carla; May, Patrick; Møller, Rikke S.; Muhle, Hiltrud; Pal, Deb; Palotie, Aarno; Pendziwitat, Manuela; Robbiano, Angela; Roelens, Filip; Rosenow, Felix; Selmer, Kaja; Serratosa, Jose M.; Sisodiya, Sanjay; Stephani, Ulrich; Sterbova, Katalin; Striano, Pasquale; Suls, Arvid; Talvik, Tiina; von Spizak, Sarah; Weber, Yvonne; Weckhuysen, Sarah; Zara, Frederico; Epilepsy Phenome/Genome Project; Epi4K Consortium

in American Journal of Human Genetics (2014), 4

Full Text
See detailDe novo mutations in HCN1 cause early infantile epileptic encephalopathy
Nava, Caroline; Dalle, Carine; Rastetter, Agnès; Striano, Pasquale; de Kovel, Carolien G. F.; Nabbout, Rima; Cancès, Claude; Ville, Dorothée; Brilstra, Eva H.; Gobbi, Giuseppe; Raffo, Emmanuel; Bouteiller, Delphine; Marie, Yannick; Trouillard, Oriane; Robbiano, Angela; Keren, Boris; Agher, Dahbia; Roze, Emmanuel; Lesage, Suzanne; Nicolas, Aude; Brice, Alexis; Baulac, Michel; Vogt, Cornelia; El Hajj, Nady; Schneider, Eberhard; Suls, Arvid; Weckhuysen, Sarah; Gormley, Padhraig; Lehesjoki, Anna-Elina; De Jonghe, Peter; Helbig, Ingo; Baulac, Stephanie; Zara, Federico; Koeleman, Bobby P. C.; Consortium, Euroepinomics R. E. S.; Haaf, Thomas; LeGuern, Eric; Depienne, Christel; May, Patrick; Balling, Rudi; Barisic, Nina; Baulac, Stéphanie; Caglayan, Hande S.; Craiu, Dana C.; De Jonghe, Peter; Depienne, Christel; Gormley, Padhraig; Guerrini, Renzo; Helbig, Ingo; Hjalgrim, Helle; Hoffman-Zacharska, Dorota; Jähn, Johanna; Klein, Karl Martin; Koeleman, Bobby P. C.; Komarek, Vladimir; Krause, Roland; LeGuern, Eric; Lehesjoki, Anna-Elina; Lemke, Johannes R.; Lerche, Holger; Marini, Carla; Møller, Rikke S.; Muhle, Hiltrud; Palotie, Aarno; Pal, Deb; Rosenow, Felix; Selmer, Kaja; Serratosa, José M.; Sisodiya, Sanjay; Stephani, Ulrich; Sterbova, Katalin; Striano, Pasquale; Suls, Arvid; Talvik, Tiina; von Spiczak, Sarah; Weber, Yvonne; Weckhuysen, Sarah; Zara, Federico

in Nature Genetics (2014)

Full Text
See detailMercator: A fast and simple web server for genome scale functional annotation of plant sequence data
Lohse, Marc; Nagel, Axel; Herter, Thomas; May, Patrick; Schroda, Michael; Zrenner, Rita; Tohge, Takayuki; Fernie, Alisdair R.; Stitt, Mark; Usadel, Bjorn

in Plant, Cell & Environment (2014), 37(5), 1250-8

Full Text
See detailPOMO - Plotting Omics analysis results for Multiple Organisms
Lin, Jake; Kreisberg, Richard; Kallio, Aleksi; Dudley, Aimee M.; Nykter, Matti; Shmulevich, Ilya; May, Patrick; Autio, Reija

in BMC Genomics (2013), 14(918),

Full Text
See detailGenomic Sequence Diversity and Population Structure of Saccharomyces cerevisiae Assessed by RAD-seq
Cromie, Gareth A.; Hyma, Katie E.; Ludlow, Catherine L.; Garmendia-Torres, Cecilia; Gilbert, Teresa L.; May, Patrick; Huang, Angela A.; Dudley, Aimée M.; Fay, Justin C.

in Genes, Genomes and Genomics (2013), 3(12), 2163-2171

Full Text
See detailThe Effects of Carbon Dioxide and Temperature on microRNA Expression in Arabidopsis Development
May, Patrick; Liao, Will; Wu, Yijin; Shuai, Bin; McCombie, W. Richard; Zhang, Michael; Liu, Qiong

in Nature Communications (2013), 4(2145),

Full Text
See detailHigh-throughput tetrad analysis
Ludlow, Catherine L.; Scott, Adrian C.; Cromie, Gareth A.; Jeffery, Eric W.; Sirr, Amy; May, Patrick; Lin, Jake; Gilbert, Teresa L.; Hays, Michelle; Dudley, Aimée M.

in Nature Methods (2013), 10

Full Text
See detailA Protein Prioritization Approach Tailored for the FA/BRCA Pathway
Haitjema, Anneke; Brandt, Bernd W.; Ameziane, Najim; May, Patrick; Heringa, Jaap; de Winter, Johan P. Joenje; Dorsman, Josephine C.

in PLoS ONE (2013), 8(4), 62017

Full Text
See detailHierarchical representation of supersecondary structures using a graph-theoretical approach.
Koch, Ina; Kreuchwig, Annika; May, Patrick

in Methods in Molecular Biology (Clifton, N.J.) (2013), 932

Full Text
See detailCondensing the omics fog of microbial communities
Muller, Emilie; Glaab, Enrico; May, Patrick; Vlassis, Nikos; Wilmes, Paul

in Trends in Microbiology (2013), 21(7), 325333

Full Text
See detailNew insights into Chlamydomonas reinhardtii hydrogen production processes by combined microarray/RNA-seq transcriptomics.
Toepel, Jorg; Illmer-Kephalides, Maike; Jaenicke, Sebastian; Straube, Jasmin; May, Patrick; Goesmann, Alexander; Kruse, Olaf

in Plant Biotechnology Journal (2013)

Full Text
See detailGive It AGO: The Search for miRNA-Argonaute Sorting Signals in Arabidopsis thaliana Indicates a Relevance of Sequence Positions Other than the 5'-Position Alone.
Thieme, Christoph J.; Schudoma, Christian; May, Patrick; Walther, Dirk

in Frontiers in Plant Science (2012), 3

Full Text
See detailDistribution pattern of small RNA and degradome reads provides information on miRNA gene structure and regulation.
Branscheid, Anja; Devers, Emanuel A.; May, Patrick; Krajinski, Franziska

in Plant signaling & behavior (2011), 6(10), 1609-11

Full Text
See detailStars and symbiosis: microRNA- and microRNA*-mediated transcript cleavage involved in arbuscular mycorrhizal symbiosis.
Devers, Emanuel A.; Branscheid, Anja; May, Patrick; Krajinski, Franziska

in Plant Physiology (2011), 156(4), 1990-2010

Full Text
See detailComparative analysis of miRNAs and their targets across four plant species.
Lenz, Dorina; May, Patrick; Walther, Dirk

in BMC Research Notes (2011), 4

Full Text
See detailIntegration of proteomic and metabolomic profiling as well as metabolic modeling for the functional analysis of metabolic networks.
May, Patrick; Christian, Nils; Ebenhoh, Oliver; Weckwerth, Wolfram; Walther, Dirk

in Methods in Molecular Biology (Clifton, N.J.) (2011), 694

Full Text
See detailExpression pattern suggests a role of MiR399 in the regulation of the cellular response to local Pi increase during arbuscular mycorrhizal symbiosis.
Branscheid, Anja; Sieh, Daniela; Pant, Bikram Datt; May, Patrick; Devers, Emanuel A.; Elkrog, Anders; Schauser, Leif; Scheible, Wolf-Rudiger; Krajinski, Franziska

in Molecular plant-microbe interactions : MPMI (2010), 23(7), 915-26

Full Text
See detailPTGL: a database for secondary structure-based protein topologies.
May, Patrick; Kreuchwig, Annika; Steinke, Thomas; Koch, Ina

in Nucleic Acids Research (2010), 38(Database issue), 326-30

Full Text
See detailAlgebraic connectivity may explain the evolution of gene regulatory networks.
Nikoloski, Zoran; May, Patrick; Selbig, Joachim

in Journal of Theoretical Biology (2010), 267(1), 7-14

Full Text
See detailSequence-structure relationships in RNA loops: establishing the basis for loop homology modeling.
Schudoma, Christian; May, Patrick; Nikiforova, Viktoria; Walther, Dirk

in Nucleic Acids Research (2010), 38(3), 970-80

Full Text
See detailModeling RNA loops using sequence homology and geometric constraints.
Schudoma, Christian; May, Patrick; Walther, Dirk

in Bioinformatics (Oxford, England) (2010), 26(13), 1671-2

Full Text
See detailTargeted proteomics for Chlamydomonas reinhardtii combined with rapid subcellular protein fractionation, metabolomics and metabolic flux analyses.
Wienkoop, Stefanie; Weiss, Julia; May, Patrick; Kempa, Stefan; Irgang, Susann; Recuenco-Munoz, Luis; Pietzke, Matthias; Schwemmer, Thorsten; Rupprecht, Jens; Egelhofer, Volker; Weckwerth, Wolfram

in Molecular Biosystems (2010), 6(6), 1018-31

Full Text
See detailIdentification and classification of ncRNA molecules using graph properties.
Childs, Liam; Nikoloski, Zoran; May, Patrick; Walther, Dirk

in Nucleic Acids Research (2009), 37(9), 66

Full Text
See detailAn integrative approach towards completing genome-scale metabolic networks.
Christian, Nils; May, Patrick; Kempa, Stefan; Handorf, Thomas; Ebenhoh, Oliver

in Molecular Biosystems (2009), 5(12), 1889-903

Full Text
See detailJAIL: a structure-based interface library for macromolecules.
Gunther, Stefan; von Eichborn, Joachim; May, Patrick; Preissner, Robert

in Nucleic Acids Research (2009), 37(Database issue), 338-41

Full Text
See detailChlamyCyc: an integrative systems biology database and web-portal for Chlamydomonas reinhardtii.
May, Patrick; Christian, Jan-Ole; Kempa, Stefan; Walther, Dirk

in BMC Genomics (2009), 10

Full Text
See detailIdentification of nutrient-responsive Arabidopsis and rapeseed microRNAs by comprehensive real-time polymerase chain reaction profiling and small RNA sequencing.
Pant, Bikram Datt; Musialak-Lange, Magdalena; Nuc, Przemyslaw; May, Patrick; Buhtz, Anja; Kehr, Julia; Walther, Dirk; Scheible, Wolf-Rudiger

in Plant Physiology (2009), 150(3), 1541-55

Full Text
See detailMetabolomics- and proteomics-assisted genome annotation and analysis of the draft metabolic network of Chlamydomonas reinhardtii.
May, Patrick; Wienkoop, Stefanie; Kempa, Stefan; Usadel, Bjorn; Christian, Nils; Rupprecht, Jens; Weiss, Julia; Recuenco-Munoz, Luis; Ebenhoh, Oliver; Weckwerth, Wolfram; Walther, Dirk

in Genetics (2008), 179(1), 157-66

Full Text
See detailMetabolic networks are NP-hard to reconstruct.
Nikoloski, Zoran; Grimbs, Sergio; May, Patrick; Selbig, Joachim

in Journal of Theoretical Biology (2008), 254(4), 807-16

See detailDocking without docking: ISEARCH--prediction of interactions using known interfaces.
Gunther, Stefan; May, Patrick; Hoppe, Andreas; Frommel, Cornelius; Preissner, Robert

in Proteins (2007), 69(4), 839-44

See detailConnectivity independent protein-structure alignment: a hierarchical approach.
Kolbeck, Bjoern; May, Patrick; Schmidt-Goenner, Tobias; Steinke, Thomas; Knapp, Ernst-Walter

in BMC Bioinformatics (2006), 7

Full Text
See detailPTGL--a web-based database application for protein topologies.
May, Patrick; Barthel, Stefan; Koch, Ina

in Bioinformatics (Oxford, England) (2004), 20(17), 3277-9

Haut de page

Scientific congresses, symposiums and conference proceedings – Papers published in a journal

Full Text
See detailIdentification and Characterization of Variant Intolerant Sites across Human Protein 3-Dimensional Structures
Iqbal, Sumaiya; Berg Jespersen, Jakob; Perez-Palma, Eduardo; May, Patrick; Heyne, Henrike; Lage, Kasper; Steensbjerre Møller, Rikke; Wagner, Florence F.; Daly, Mark; Campbell, Arthur J.; Lal, Dennis

in Biophysical Journal (2018, February 02), 114(3, Suppl. 1), 664

Full Text
See detailDiscovery and pathogenicity assessment of neuropathology-associated gene variants
Neupert, Lisa-Marie; May, Patrick; Kobow, Katja; Nothnagel, Michael; Nürnberg, Peter; Freiman, Thomas; Harter, Patrick; Klein, Karl-Martin; Weber, Yvonne; Blümcke, Ingmar; Lal, Dennis

in Epilepsia (2017, December 08), 58(Suppl.5), 174

Full Text
See detailRare variant analysis of the PPMI dataset to uncover the complex genetic architecture of Parkinson’s disease
Bobbili, Dheeraj Reddy; May, Patrick; Krüger, Rejko

in Movement Disorders : Official Journal of the Movement Disorder Society (2017, June 02), 322(Supplement S2), 405

Full Text
See detailIDENTIFICATION OF A RARE GENE VARIANT THAT IS ASSOCIATED WITH FAMILIAL ALZHEIMER DISEASE AND REGULATES APP EXPRESSION
Hartl, Daniela; May, Patrick; Gu, Wei; Mayhaus, Manuel; Glaab, Enrico; Antony, Paul; Bobbili, Dheeraj Reddy; Köglsberger, Sandra; Pichler, Sabrina; Spaniol, Christian; Kurz, Alexander; Balling, Rudi; Schneider, Jochen; Riemenschneider, Matthias

in Alzheimer's & Dementia : The Journal of the Alzheimer's Association (2017), 13(7, Supplement), 648

See detail“Melanomics”: analysis and integration of whole genomes, transcriptomes and miRNomes of primary melanoma patients
Reinsbach, Susanne; Wienecke, Anke; Ginolhac, Aurélien; Vallar, Laurent; Krishna; Krishna, Abhimanyu; Nazarov, Petr; May, Patrick; Kreis, Stephanie

in European Journal of Cancer (2016), 61(Suppl.1), 32

Haut de page

Contributions to collective works

See detailExtraction and Analysis of RNA Isolated from Pure Bacteria-Derived Outer Membrane Vesicles
Habier, Janine; May, Patrick; Heintz-Buschart, Anna; Ghosal, Anubrata; Wienecke-Baldacchino, Anke; Nolte-'t Hoen, Esther N.M; Wilmes, Paul; Fritz, Joëlle

in Arluison, Véronique; Valverde, Claudio Valverde (Eds.) Bacterial Regulatory RNA (2018)

Haut de page

Scientific congresses, symposiums and conference proceedings – Papers published in a book

Full Text
See detailVariant-DB: A Tool for Efficiently Exploring Millions of Human Genetic Variants and Their Annotations
Kutzera, Joachim; May, Patrick

in Da Silveira, Marcos; Pruski, Cédric; Schneider, Reinhard (Eds.) DILS 2017: Data Integration in the Life Sciences (2017, October 24)

Full Text
See detailEvaluation of Cell Line Suitability for Disease Specific Perturbation Experiments.
Biryukov, Maria; Antony, Paul; Krishna, Abhimanyu; May, Patrick; Trefois, Christophe

in Lausen, Berthold; Krolak-Schwerdt, Sabine; Böhmer, Matthias (Eds.) Data Science, Learning by Latent Structures, and Knowledge Discovery (2015, February 20)

Full Text
See detailComputation and Visualization of Protein Topology Graphs Including Ligand Information
Schäfer, Tim; May, Patrick; Koch, Ina

in Böcker, Sebasttian; Hufsky, Franziska; Scheubert, Kerstin; Schleicher, Jana; Schuster, Stefan (Eds.) German Conference on Bioinformatics 2012 (2012)

See detailAccelerated microRNA-Precursor Detection Using the Smith-Waterman Algorithm on FPGAs
May, Patrick; Klau, Gunnar W.; Bauer, Markus; Steinke, Thomas

in Dubitzky, Werner; Schuster, Assaf; Sloot, Peterm A.; Schroeder, Michael; Romberg, Mathilde (Eds.) Distributed, High-Performance and Grid Computing in Computational Biology (2007)

See detailZIB Structure Prediction Pipeline: Composing a Complex Biological Workflow through Web Services
May, Patrick; Ehrlich, Hans-Christian; Steinke, Thomas

in Nagel, Wolfgang E.; Walter, Wolfgang V.; Lehner, Wolfgang (Eds.) Euro-Par 2006 Parallel Processing (2006)

Haut de page

E-Prints/Working papers – already available on another site

Full Text
See detailIsolation of nucleic acids from low biomass samples: detection and removal of sRNA contaminants
Heintz-Buschart, Anna; Yusuf, Dilmurat; Kaysen, Anne; Etheridge, Alton; Fritz, Joëlle; May, Patrick; de Beaufort, Carine; Upadhyaya, Bimal Babu; Ghosal, Anubrata; Galas, David J.; Wilmes, Paul

E-print/Working paper (2017)

Full Text
See detailThe Spectrum Of De Novo Variants In Neurodevelopmental Disorders With Epilepsy
Heyne, Henrike O.; EuroEPINOMICS RES Consortium; Abou Jamra, Rami; Caglayan, Hande; Craiu, Dana; De Jonghe, Peter; Guerrini, Renzo; Helbig, Katherine L.; Koeleman, Bobby P. C.; Kosmicki, Jack A.; Linnankivi, Tarja; May, Patrick; Muhle, Hiltrud; Moeller, Rikke S.; Neubauer, Bernd; Palotie, Aarno; Pendziwiat, Manuela; Stamberger, Hannah; Striano, Pasquale; Tang, Sha; Wu, Sitao; Daly, Mark J.; Poduri, Annapurna; Weber, Yvonne; Weckhuysen, Sarah; Sisodiya, Sanjay M.; Helbig, Ingo; Lal, Dennis; Lemke, Johannes R.

E-print/Working paper (2017)

Full Text
See detailReassessment Of Lesion-Associated Gene And Variant Pathogenicity In Focal Human Epilepsies
Neupert, Lisa Marie; Nothnagel, Michael; May, Patrick; Palotie, Aarno; Daly, Mark; Nürnberg, Peter; Blümcke, Ingmar; Lal, Dennis

E-print/Working paper (2017)

Haut de page

Scientific congresses, symposiums and conference proceedings – Unpublished conferences

See detailCommunity integrated omics links the dominance of a microbial generalist to fine-tuned resource usage
Muller, Emilie; Pinel, Nicolás; Laczny, Cédric; Hoopmann, Michael; Lebrun, Laura; Roume, Hugo; May, Patrick; Hicks, Nathan; Liu, Cindy; Price, Lance; Gillece, John; Guignard, Cédric; Schupp, James; Vlassis, Nikos; Moritz, Robert; Baliga, Nitin; Keim, Paul; Wilmes, Paul

Scientific Conference (2014)

Haut de page

Scientific congresses, symposiums and conference proceedings – Posters

See detailIntegrated Omic Analyses of the Human Gut Microbiome in a Multiplex Family Study of Type 1 Diabetes Mellitus
Heintz, Anna; May, Patrick; Laczny, Cédric; Lebrun, Laura; Wampach, Linda; Hogan, Angela; Schneider, Jochen; Wilmes, Paul; De Beaufort, Carine

Poster (2014, April 30)

See detailCommunity integrated omics links the dominance of a microbial generalist to fine-tuned resource usage
Muller, Emilie; Pinel, Nicolás; Laczny, Cédric; Hoopmann, Michael; Lebrun, Laura; Roume, Hugo; May, Patrick; Hicks, Nathan; Liu, Cindy; Price, Lance; Gillece, John; Guignard, Cédric; Schupp, James; Vlassis, Nikos; Moritz, Robert; Baliga, Nitin; Keim, Paul; Wilmes, Paul

Poster (2014)

See detailDifferentiated SH-SY5Y Cells as PD Model for Mitochondrial Dysfunction: From Whole Genome Sequencing to an Educated Design of High-Throughput Experiments
Antony, Paul; Krishna, Abhimanyu; May, Patrick; Trefois, Christophe; Boyd, Olga; Köglsberger, Sandra; Baumuratov, Aidos; Galas, David J.; Balling, Rudi

Poster (2013)

See detailSystematic molecular measurements reveal key microbial populations driving community-wide phenotype
Muller, Emilie; Pinel, Nicolás; May, Patrick; Hussong, René; Roume, Hugo; Lebrun, Laura; liu, Cindy; Aziz, Maliha; Price, Lance; Moritz, Robert; Schupp, James; Keim, Paul; Wilmes, Paul

Poster (2013)

See detailLinking mixed microbial community phenotype to individual genotypes
Muller, Emilie; Pinel, Nicolás; May, Patrick; Roume, Hugo; Wilmes, Paul

Poster (2013)

See detailA model microbial community for Eco-Systems Biology
Muller, Emilie; Roume, Hugo; Buschart, Anna; Pinel, Nicolas; Laczny, Cédric; Satagopam, Venkata; May, Patrick; Lebrun, Laura; Wilmes, Paul

Poster (2013)

See detailIntegrated omics highlights keystone genes in community-wide metabolic networks
Roume, Hugo; Satagopam, Venkata; Muller, Emilie; May, Patrick; Hussong, René; Wilmes, Paul

Poster (2013)

See detailIntegrated omics highlights keystone genes in community-wide metabolic networks
Roume, Hugo; Satagopam, Venkata; Muller, Emilie; May, Patrick; Hussong, René; Wilmes, Paul

Poster (2013)

See detailChlamyCyc--a comprehensive database and web-portal centered on Chlamydomonas reinhardtii
Christian, Jan-Ole; May, Patrick; Kempa, Stefan; Walther, Dirk

Poster (2009)

Haut de page

External Reports

Full Text
See detailA computational approach to microRNA detection
May, Patrick; Bauer, Markus; Köberle, Christian; Klau, Gunnar

Report (2006)

Full Text
See detailTHESEUS - Protein Structure Prediction at ZIB
May, Patrick; Steinke, Thomas

Report (2006)

Haut de page