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Dr. Roland Krause

Roland Krause

Research scientist

Academic Area(s) Computer science / Multidisciplinary, general & others / Neurology / Genetics & genetic processes
Research Topics Bioinformatics, Epilepsy Genetics, Genomics
Faculty or Centre Luxembourg Centre for Systems Biomedicine
Department Bioinformatics Core
Postal Address Université du Luxembourg
2, Avenue de l'Université
L-4365 Esch-sur-Alzette
Email
Telephone (+352) 46 66 44 6267
Fax (+352) 46 66 44 36267
Social Media & Blogs
Speaks English, French, German
Research Stays in Germany, Luxembourg, USA

Postdoc in the Bioinformatics Core group (R. Schneider Lab)

Last updated on: Wednesday, 02 September 2015

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In press

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See detailGene selection for optimal prediction of cell position in tissues from single-cell transcriptomics
Tanevski, Jovan; Nguyen, Thin; Truong, Buu; Karaiskos, Nikolaos; Eren, Mehmet; Zhang, Xinyu; Shu, Chang; Hu, Ying; Pham, Hoang V. V.; Li, Xiaomei; Le, Thuc; Tarca, Adi; Bhatti, Gaurav; Romero, Roberto; Karathanasis, Nestoras; Loher, Phillipe; Chen, Yang; Ouyang, Zhengqing; Mao, Disheng; Zhang, Yuping; Zand, Maryam; Ruan, Jianhua; Hafemeister, Christoph; Qiu, Peng; Tran, Duc; Nguyen, Tin; Gabor, Attila; Yu, Thomas; Glaab, Enrico; Krause, Roland; Banda, Peter; Stolovitzky, Gustavo; Rajewsky, Nikolaus; Saez-Rodriguez, Julio

in Life Science Alliance (in press)

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2021

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See detailClimate change and epilepsy: Insights from clinical and basic science studies
Gulcebi, Medine I.; Bartolini, Emanuele; Lee, Omay; Lisgaras, Christos Panagiotis; Onat, Filiz; Mifsud, Janet; Striano, Pasquale; Vezzani, Annamaria; Hildebrand, Michael S.; Jimenez-Jimenez, Diego; Junck, Larry; Lewis-Smith, David; Scheffer, Ingrid E.; Thijs, Roland D.; Zuberi, Sameer M.; Blenkinsop, Stephen; Fowler, Hayley J.; Foley, Aideen; Balestrini, Simona; Berkovic, Samuel; Cavalleri, Gianpiero; Correa, Daniel José; Custodio, Helena Martins; Galovic, Marian; Guerrini, Renzo; Henshall, David; Howard, Olga; Hughes, Kelvin; Katsarou, Anna; Koeleman, Bobby P. C.; Krause, Roland; Lowenstein, Daniel; Mandelenaki, Despoina; Marini, Carla; O'Brien, Terence J.; Pace, Adrian; Palma, Luca De; Perucca, Piero; Pitkänen, Asla; Quinn, Finola; Selmer, Kaja Kristine; Steward, Charles A.; Swanborough, Nicola; Thijs, Roland; Tittensor, Phil; Trivisano, Marina; Weckhuysen, Sarah; Zara, Federico; Sisodiya, Sanjay M.

in Epilepsy and Behavior (2021), 116

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See detailUltra-rare constrained missense variants in the epilepsies: Shared and specific enrichment patterns in neuronal gene-sets 2021.04.18.440264
Koko, Mahmoud; Krause, Roland; Sander, Thomas; Bobbili, Dheeraj Reddi; Nothnagel, Michael; May, Patrick; Lerche, Holger; ???

E-print/Working paper (2021)

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See detailLoss of function variants in the KCNQ5 gene are associated with genetic generalized epilepsies
Krueger, Johanna; Schubert, Julian; Kegele, Josua; Labalme, Audrey; Mao, Miaomiao; Heighway, Jaqueline; Seebohm, Guiscard; Yan, Pu; Koko, Mahmoud; Aslan, Kezban; Caglayan, Hande; Steinhoff, Bernhard J.; Weber, Yvonne G.; Keo-Kosal, Pascale; Berkovic, Samuel F.; Hildebrand, Michael S.; Petrou, Steven; Krause, Roland; May, Patrick; Lesca, Gaetan; Maljevic, Snezana; Lerche, Holger

E-print/Working paper (2021)

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See detailModeling seizures in the Human Phenotype Ontology according to contemporary ILAE concepts makes big phenotypic data tractable
Lewis-Smith, David; Galer, Peter D.; Balagura, Ganna; Kearney, Hugh; Ganesan, Shiva; Cosico, Mahgenn; O'Brien, Margaret; Vaidiswaran, Priya; Krause, Roland; Ellis, Colin A.; Thomas, Rhys H.; Robinson, Peter N.; Helbig, Ingo

in Epilepsia (2021), n/a(n/a),

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See detailSub-genic intolerance, ClinVar, and the epilepsies: A whole-exome sequencing study of 29,165 individuals
Motelow, Joshua E.; Povysil, Gundula; Dhindsa, Ryan S.; Stanley, Kate E.; Allen, Andrew S.; Feng, Yen-Chen Anne; Howrigan, Daniel P.; Abbott, Liam E.; Tashman, Katherine; Cerrato, Felecia; Cusick, Caroline; Singh, Tarjinder; Heyne, Henrike; Byrnes, Andrea E.; Churchhouse, Claire; Watts, Nick; Solomonson, Matthew; Lal, Dennis; Gupta, Namrata; Neale, Benjamin M.; Cavalleri, Gianpiero L.; Cossette, Patrick; Cotsapas, Chris; Jonghe, Peter De; Dixon-Salazar, Tracy; Guerrini, Renzo; Hakonarson, Hakon; Heinzen, Erin L.; Helbig, Ingo; Kwan, Patrick; Marson, Anthony G.; Petrovski, Slavé; Kamalakaran, Sitharthan; Sisodiya, Sanjay M.; Stewart, Randy; Weckhuysen, Sarah; Depondt, Chantal; Dlugos, Dennis J.; Scheffer, Ingrid E.; Striano, Pasquale; Freyer, Catharine; Krause, Roland; May, Patrick; McKenna, Kevin; Regan, Brigid M.; Bennett, Caitlin A.; Leu, Costin; Leech, Stephanie L.; O’Brien, Terence J.; Todaro, Marian; Stamberger, Hannah; Andrade, Danielle M.; Ali, Quratulain Zulfiqar; Sadoway, Tara R.; Krestel, Heinz; Schaller, André; Papacostas, Savvas S.; Kousiappa, Ioanna; Tanteles, George A.; Christou, Yiolanda; Štěrbová, Katalin; Vlčková, Markéta; Sedláčková, Lucie; Laššuthová, Petra; Klein, Karl Martin; Rosenow, Felix; Reif, Philipp S.; Knake, Susanne; Neubauer, Bernd A.; Zimprich, Friedrich; Feucht, Martha; Reinthaler, Eva M.; Kunz, Wolfram S.; Zsurka, Gábor; Surges, Rainer; Baumgartner, Tobias; Wrede, Randi Von; Pendziwiat, Manuela; Muhle, Hiltrud; Rademacher, Annika; Baalen, Andreas Van; Spiczak, Sarah Von; Stephani, Ulrich; Afawi, Zaid; Korczyn, Amos D.; Kanaan, Moien; Canavati, Christina; Kurlemann, Gerhard; Müller-Schlüter, Karen; Kluger, Gerhard; Häusler, Martin; Blatt, Ilan; Lemke, Johannes R.; Krey, Ilona; Weber, Yvonne G.; Wolking, Stefan; Becker, Felicitas; Lauxmann, Stephan; Boßelmann, Christian; Kegele, Josua; Hengsbach, Christian; Rau, Sarah; Steinhoff, Bernhard J.; Schulze-Bonhage, Andreas; Borggräfe, Ingo; Schankin, Christoph J.; Schubert-Bast, Susanne; Schreiber, Herbert; Mayer, Thomas; Korinthenberg, Rudolf; Brockmann, Knut; Wolff, Markus; Dennig, Dieter; Madeleyn, Rene; Kälviäinen, Reetta; Saarela, Anni; Timonen, Oskari; Linnankivi, Tarja; Lehesjoki, Anna-Elina; Rheims, Sylvain; Lesca, Gaetan; Ryvlin, Philippe; Maillard, Louis; Valton, Luc; Derambure, Philippe; Bartolomei, Fabrice; Hirsch, Edouard; Michel, Véronique; Chassoux, Francine; Rees, Mark I.; Chung, Seo-Kyung; Pickrell, William O.; Powell, Robert; Baker, Mark D.; Fonferko-Shadrach, Beata; Lawthom, Charlotte; Anderson, Joseph; Schneider, Natascha; Balestrini, Simona; Zagaglia, Sara; Braatz, Vera; Johnson, Michael R.; Auce, Pauls; Sills, Graeme J.; Baum, Larry W.; Sham, Pak C.; Cherny, Stacey S.; Lui, Colin H. T.; Delanty, Norman; Doherty, Colin P.; Shukralla, Arif; El-Naggar, Hany; Widdess-Walsh, Peter; Barišić, Nina; Canafoglia, Laura; Franceschetti, Silvana; Castellotti, Barbara; Granata, Tiziana; Ragona, Francesca; Zara, Federico; Iacomino, Michele; Riva, Antonella; Madia, Francesca; Vari, Maria Stella; Salpietro, Vincenzo; Scala, Marcello; Mancardi, Maria Margherita; Nobili, Lino; Amadori, Elisabetta; Giacomini, Thea; Bisulli, Francesca; Pippucci, Tommaso; Licchetta, Laura; Minardi, Raffaella; Tinuper, Paolo; Muccioli, Lorenzo; Mostacci, Barbara; Gambardella, Antonio; Labate, Angelo; Annesi, Grazia; Manna, Lorella; Gagliardi, Monica; Parrini, Elena; Mei, Davide; Vetro, Annalisa; Bianchini, Claudia; Montomoli, Martino; Doccini, Viola; Barba, Carmen; Hirose, Shinichi; Ishii, Atsushi; Suzuki, Toshimitsu; Inoue, Yushi; Yamakawa, Kazuhiro; Beydoun, Ahmad; Nasreddine, Wassim; Zgheib, Nathalie Khoueiry; Tumiene, Birute; Utkus, Algirdas; Sadleir, Lynette G.; King, Chontelle; Caglayan, S. Hande; Arslan, Mutluay; Yapıcı, Zuhal; Topaloglu, Pınar; Kara, Bulent; Yis, Uluc; Turkdogan, Dilsad; Gundogdu-Eken, Aslı; Bebek, Nerses; Tsai, Meng-Han; Ho, Chen-Jui; Lin, Chih-Hsiang; Lin, Kuang-Lin; Chou, I.-Jun; Poduri, Annapurna; Shiedley, Beth R.; Shain, Catherine; Noebels, Jeffrey L.; Goldman, Alicia; Busch, Robyn M.; Jehi, Lara; Najm, Imad M.; Ferguson, Lisa; Khoury, Jean; Glauser, Tracy A.; Clark, Peggy O.; Buono, Russell J.; Ferraro, Thomas N.; Sperling, Michael R.; Lo, Warren; Privitera, Michael; French, Jacqueline A.; Schachter, Steven; Kuzniecky, Ruben I.; Devinsky, Orrin; Hegde, Manu; Greenberg, David A.; Ellis, Colin A.; Goldberg, Ethan; Helbig, Katherine L.; Cosico, Mahgenn; Vaidiswaran, Priya; Fitch, Eryn; Berkovic, Samuel F.; Lerche, Holger; Lowenstein, Daniel H.; Goldstein, David B.

in The American Journal of Human Genetics (2021)

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See detailRole of Common Genetic Variants for Drug-Resistance to Specific Anti-Seizure Medications
Wolking, Stefan; Campbell, Ciarán; Stapleton, Caragh; McCormack, Mark; Delanty, Norman; Depondt, Chantal; Johnson, Michael R.; Koeleman, Bobby P. C.; Krause, Roland; Kunz, Wolfram S.; Marson, Anthony G.; Sander, Josemir W.; Sills, Graeme J.; Striano, Pasquale; Zara, Federico; Sisodiya, Sanjay M.; Cavalleri, Gianpiero L.; Lerche, Holger; ???, Epipgx Consortium

in Frontiers in Pharmacology (2021), 12

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See detailAssessing the role of rare genetic variants in drug-resistant, non-lesional focal epilepsy
Wolking, Stefan; Moreau, Claudia; McCormack, Mark; Krause, Roland; Krenn, Martin; Consortium, Epipgx; Berkovic, Samuel; Cavalleri, Gianpiero L.; Delanty, Norman; Depondt, Chantal; Johnson, Michael R.; Koeleman, Bobby P. C.; Kunz, Wolfram S.; Lerche, Holger; Marson, Anthony G.; O’Brien, Terence J.; Petrovski, Slave; Sander, Josemir W.; Sills, Graeme J.; Striano, Pasquale; Zara, Federico; Zimprich, Fritz; Sisodiya, Sanjay M.; Girard, Simon L.; Cossette, Patrick

in Annals of Clinical and Translational Neurology (2021), n/a(n/a),

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2020

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See detailSemantic Similarity Analysis Reveals Robust Gene-Disease Relationships in Developmental and Epileptic Encephalopathies
Galer, Peter D.; Ganesan, Shiva; Lewis-Smith, David; McKeown, Sarah E.; Pendziwiat, Manuela; Helbig, Katherine L.; Ellis, Colin A.; Rademacher, Annika; Smith, Lacey; Poduri, Annapurna; Seiffert, Simone; Spiczak, Sarah Von; Muhle, Hiltrud; Baalen, Andreas Van; Thomas, Rhys H.; Krause, Roland; Weber, Yvonne; Helbig, Ingo

in The American Journal of Human Genetics (2020), 107(4), 683-697

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See detailTen simple rules for making training materials FAIR.
Garcia, Leyla; Batut, Bérénice; Burke, Melissa L.; Kuzak, Mateusz; Psomopoulos, Fotis; Arcila, Ricardo; Attwood, Teresa K.; Beard, Niall; Carvalho-Silva, Denise; Dimopoulos, Alexandros C.; Del Angel, Victoria Dominguez; Dumontier, Michel; Gurwitz, Kim T.; Krause, Roland; McQuilton, Peter; Le Pera, Loredana; Morgan, Sarah L.; Rauste, Päivi; Via, Allegra; Kahlem, Pascal; Rustici, Gabriella; van Gelder, Celia W. G.; Palagi, Patricia M.

in PLoS computational biology (2020), 16(5), 1007854

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See detailA framework to assess the quality and impact of bioinformatics training across ELIXIR.
Gurwitz, Kim T.; Singh Gaur, Prakash; Bellis, Louisa J.; Larcombe, Lee; Alloza, Eva; Balint, Balint Laszlo; Botzki, Alexander; Dimec, Jure; Dominguez Del Angel, Victoria; Fernandes, Pedro L.; Korpelainen, Eija; Krause, Roland; Kuzak, Mateusz; Le Pera, Loredana; Leskošek, Brane; Lindvall, Jessica M.; Marek, Diana; Martinez, Paula A.; Muyldermans, Tuur; Nygård, Ståle; Palagi, Patricia M.; Peterson, Hedi; Psomopoulos, Fotis; Spiwok, Vojtech; van Gelder, Celia W. G.; Via, Allegra; Vidak, Marko; Wibberg, Daniel; Morgan, Sarah L.; Rustici, Gabriella

in PLoS computational biology (2020), 16(7), 1007976

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See detailPredicting functional effects of missense variants in voltage-gated sodium and calcium channels
Heyne, Henrike O.; Baez-Nieto, David; Iqbal, Sumaiya; Palmer, Duncan S.; Brunklaus, Andreas; May, Patrick; EPI25 Collaborative; Krause, Roland; Johannesen, Katrine M.; Lauxmann, Stephan; Lemke, Johannes R.; Møller, Rikke S.; Pérez-Palma, Eduardo; Scholl, Ute I.; Syrbe, Steffen; Lerche, Holger; Lal, Dennis; Campbell, Arthur J.; Wang, Hoa-Ran; Pan, Jen; Daly, Mark J.

in Science Translational Medicine (2020), 12(556), 6848

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See detailThe Human Phenotype Ontology in 2021.
Köhler, Sebastian; Gargano, Michael; Matentzoglu, Nicolas; Carmody, Leigh C.; Lewis-Smith, David; Vasilevsky, Nicole A.; Danis, Daniel; Balagura, Ganna; Baynam, Gareth; Brower, Amy M.; Callahan, Tiffany J.; Chute, Christopher G.; Est, Johanna L.; Galer, Peter D.; Ganesan, Shiva; Griese, Matthias; Haimel, Matthias; Pazmandi, Julia; Hanauer, Marc; Harris, Nomi L.; Hartnett, Michael J.; Hastreiter, Maximilian; Hauck, Fabian; He, Yongqun; Jeske, Tim; Kearney, Hugh; Kindle, Gerhard; Klein, Christoph; Knoflach, Katrin; Krause, Roland; Lagorce, David; McMurry, Julie A.; Miller, Jillian A.; Munoz-Torres, Monica C.; Peters, Rebecca L.; Rapp, Christina K.; Rath, Ana M.; Rind, Shahmir A.; Rosenberg, Avi Z.; Segal, Michael M.; Seidel, Markus G.; Smedley, Damian; Talmy, Tomer; Thomas, Yarlalu; Wiafe, Samuel A.; Xian, Julie; Yüksel, Zafer; Helbig, Ingo; Mungall, Christopher J.; Haendel, Melissa A.; Robinson, Peter N.

in Nucleic acids research (2020)

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See detailGene family information facilitates variant interpretation and identification of disease-associated genes in neurodevelopmental disorders
Lal, Dennis; May, Patrick; Perez-Palma, Eduardo; Samocha, Kaitlin E.; Kosmicki, Jack A.; Robinson, Elise B.; Møller, Rikke S.; Krause, Roland; Nürnberg, Peter; Weckhuysen, Sarah; De Jonghe, Peter; Guerrini, Renzo; Niestroj, Lisa M.; Du, Juliana; Marini, Carla; EuroEPINOMICS-RES Consortium; Ware, James S.; Kurki, Mitja; Gormley, Padhraig; Tang, Sha; Wu, Sitao; Biskup, Saskia; Poduri, Annapurna; Neubauer, Bernd A.; Koeleman, Bobby P.C.; Helbig, Katherine L.; Weber, Yvonne G.; Helbig, Ingo; Majitha, Amit R.; Palotie, Aarno; Daly, Mark J.

in Genome Medicine (2020), 12(28),

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See detailTesting association of rare genetic variants with resistance to three common antiseizure medications
Wolking, Stefan; Moreau, Claudia; Nies, Anne T.; Schaeffeler, Elke; McCormack, Mark; Auce, Pauls; Avbersek, Andreja; Becker, Felicitas; Krenn, Martin; Møller, Rikke S.; Nikanorova, Marina; Weber, Yvonne G.; Weckhuysen, Sarah; Cavalleri, Gianpiero L.; Delanty, Norman; Depondt, Chantal; Johnson, Michael R.; Koeleman, Bobby P. C.; Kunz, Wolfram S.; Marson, Anthony G.; Sander, Josemir W.; Sills, Graeme J.; Striano, Pasquale; Zara, Federico; Zimprich, Fritz; Schwab, Matthias; Krause, Roland; Sisodiya, Sanjay M.; Cossette, Patrick; Girard, Simon L.; Lerche, Holger; EpiPGX Consortium

in Epilepsia (2020), 61(n/a), 657-666

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See detailPharmacoresponse in genetic generalized epilepsy: a genome-wide association study
Wolking, Stefan; Schulz, Herbert; Nies, Anne T.; McCormack, Mark; Schaeffeler, Elke; Auce, Pauls; Avbersek, Andreja; Becker, Felicitas; Klein, Karl M.; Krenn, Martin; Møller, Rikke S.; Nikanorova, Marina; Weckhuysen, Sarah; Consortium, Epipgx; Cavalleri, Gianpiero L.; Delanty, Norman; Depondt, Chantal; Johnson, Michael R.; Koeleman, Bobby P. C.; Kunz, Wolfram S.; Marson, Anthony G.; Sander, Josemir W.; Sills, Graeme J.; Striano, Pasquale; Zara, Federico; Zimprich, Fritz; Weber, Yvonne G.; Krause, Roland; Sisodiya, Sanjay; Schwab, Matthias; Sander, Thomas; Lerche, Holger

in Pharmacogenomics (2020), 0(0),

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2019

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See detailA genome-wide association study of sodium levels and drug metabolism in an epilepsy cohort treated with carbamazepine and oxcarbazepine
Berghuis, B; Stapleton, C; Sonsma, ACM; Hulst, J; de Haan, GJ; Lindhout, D; Demurtas, R; Balling, Rudolf; Schneider, Reinhard; EpiPGX Consortium; Krause, Roland; et al.

in Epilepsia Open (2019)

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See detailUltra-Rare Genetic Variation in the Epilepsies: A Whole-Exome Sequencing Study of 17,606 Individuals
Feng, Yen-Chen Anne; Howrigan, Daniel P.; Abbott, Liam E.; Tashman, Katherine; Cerrato, Felecia; Singh, Tarjinder; Heyne, Henrike; Byrnes, Andrea; Churchhouse, Claire; Watts, Nick; Solomonson, Matthew; Lal, Dennis; Heinzen, Erin L.; Dhindsa, Ryan S.; Stanley, Kate E.; Cavalleri, Gianpiero L.; Hakonarson, Hakon; Helbig, Ingo; Krause, Roland; May, Patrick; Weckhuysen, Sarah; Petrovski, Slavé; Kamalakaran, Sitharthan; Sisodiya, Sanjay M.; Cossette, Patrick; Cotsapas, Chris; Jonghe, Peter De; Dixon-Salazar, Tracy; Guerrini, Renzo; Kwan, Patrick; Marson, Anthony G.; Stewart, Randy; Depondt, Chantal; Dlugos, Dennis J.; Scheffer, Ingrid E.; Striano, Pasquale; Freyer, Catharine; McKenna, Kevin; Regan, Brigid M.; Bellows, Susannah T.; Leu, Costin; Bennett, Caitlin A.; Johns, Esther M. C.; Macdonald, Alexandra; Shilling, Hannah; Burgess, Rosemary; Weckhuysen, Dorien; Bahlo, Melanie; O’Brien, Terence J.; Todaro, Marian; Stamberger, Hannah; Andrade, Danielle M.; Sadoway, Tara R.; Mo, Kelly; Krestel, Heinz; Gallati, Sabina; Papacostas, Savvas S.; Kousiappa, Ioanna; Tanteles, George A.; Štěrbová, Katalin; Vlčková, Markéta; Sedláčková, Lucie; Laššuthová, Petra; Klein, Karl Martin; Rosenow, Felix; Reif, Philipp S.; Knake, Susanne; Kunz, Wolfram S.; Zsurka, Gábor; Elger, Christian E.; Bauer, Jürgen; Rademacher, Michael; Pendziwiat, Manuela; Muhle, Hiltrud; Rademacher, Annika; Baalen, Andreas Van; Spiczak, Sarah Von; Stephani, Ulrich; Afawi, Zaid; Korczyn, Amos D.; Kanaan, Moien; Canavati, Christina; Kurlemann, Gerhard; Müller-Schlüter, Karen; Kluger, Gerhard; Häusler, Martin; Blatt, Ilan; Lemke, Johannes R.; Krey, Ilona; Weber, Yvonne G.; Wolking, Stefan; Becker, Felicitas; Hengsbach, Christian; Rau, Sarah; Maisch, Ana F.; Steinhoff, Bernhard J.; Schulze-Bonhage, Andreas; Schubert-Bast, Susanne; Schreiber, Herbert; Borggräfe, Ingo; Schankin, Christoph J.; Mayer, Thomas; Korinthenberg, Rudolf; Brockmann, Knut; Kurlemann, Gerhard; Dennig, Dieter; Madeleyn, Rene; Kälviäinen, Reetta; Auvinen, Pia; Saarela, Anni; Linnankivi, Tarja; Lehesjoki, Anna-Elina; Rees, Mark I.; Chung, Seo-Kyung; Pickrell, William O.; Powell, Robert; Schneider, Natascha; Balestrini, Simona; Zagaglia, Sara; Braatz, Vera; Johnson, Michael R.; Auce, Pauls; Sills, Graeme J.; Baum, Larry W.; Sham, Pak C.; Cherny, Stacey S.; Lui, Colin H. T.; Barišić, Nina; Delanty, Norman; Doherty, Colin P.; Shukralla, Arif; McCormack, Mark; El-Naggar, Hany; Canafoglia, Laura; Franceschetti, Silvana; Castellotti, Barbara; Granata, Tiziana; Zara, Federico; Iacomino, Michele; Madia, Francesca; Vari, Maria Stella; Mancardi, Maria Margherita; Salpietro, Vincenzo; Bisulli, Francesca; Tinuper, Paolo; Licchetta, Laura; Pippucci, Tommaso; Stipa, Carlotta; Minardi, Raffaella; Gambardella, Antonio; Labate, Angelo; Annesi, Grazia; Manna, Lorella; Gagliardi, Monica; Parrini, Elena; Mei, Davide; Vetro, Annalisa; Bianchini, Claudia; Montomoli, Martino; Doccini, Viola; Marini, Carla; Suzuki, Toshimitsu; Inoue, Yushi; Yamakawa, Kazuhiro; Tumiene, Birute; Sadleir, Lynette G.; King, Chontelle; Mountier, Emily; Caglayan, S. Hande; Arslan, Mutluay; Yapıcı, Zuhal; Yis, Uluc; Topaloglu, Pınar; Kara, Bulent; Turkdogan, Dilsad; Gundogdu-Eken, Aslı; Bebek, Nerses; Uğur-İşeri, Sibel; Baykan, Betül; Salman, Barış; Haryanyan, Garen; Yücesan, Emrah; Kesim, Yeşim; Özkara, Çiğdem; Poduri, Annapurna; Shiedley, Beth R.; Shain, Catherine; Buono, Russell J.; Ferraro, Thomas N.; Sperling, Michael R.; Lo, Warren; Privitera, Michael; French, Jacqueline A.; Schachter, Steven; Kuzniecky, Ruben I.; Devinsky, Orrin; Hegde, Manu; Khankhanian, Pouya; Helbig, Katherine L.; Ellis, Colin A.; Spalletta, Gianfranco; Piras, Fabrizio; Piras, Federica; Gili, Tommaso; Ciullo, Valentina; Reif, Andreas; McQuillin, Andrew; Bass, Nick; McIntosh, Andrew; Blackwood, Douglas; Johnstone, Mandy; Palotie, Aarno; Pato, Michele T.; Pato, Carlos N.; Bromet, Evelyn J.; Carvalho, Celia Barreto; Achtyes, Eric D.; Azevedo, Maria Helena; Kotov, Roman; Lehrer, Douglas S.; Malaspina, Dolores; Marder, Stephen R.; Medeiros, Helena; Morley, Christopher P.; Perkins, Diana O.; Sobell, Janet L.; Buckley, Peter F.; Macciardi, Fabio; Rapaport, Mark H.; Knowles, James A.; Fanous, Ayman H.; McCarroll, Steven A.; Gupta, Namrata; Gabriel, Stacey B.; Daly, Mark J.; Lander, Eric S.; Lowenstein, Daniel H.; Goldstein, David B.; Lerche, Holger; Berkovic, Samuel F.; Neale, Benjamin M.

in American Journal of Human Genetics (2019)

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See detailGenomic and clinical predictors of lacosamide response in refractory epilepsies
Heavin, Sinéad B.; McCormack, Mark; Wolking, Stefan; Slattery, Lisa; Walley, Nicole; Avbersek, Andreja; Novy, Jan; Sinha, Saurabh R.; Radtke, Rod; Doherty, Colin; Auce, Pauls; Craig, John; Johnson, Michael R.; Koeleman, Bobby P. C.; Krause, Roland; Kunz, Wolfram S.; Marson, Anthony G.; O'Brien, Terence J.; Sander, Josemir W.; Sills, Graeme J.; Stefansson, Hreinn; Striano, Pasquale; Zara, Federico; EPIGEN Consortium; EpiPGX Consortium; Depondt, Chantal; Sisodiya, Sanjay; Goldstein, David; Lerche, Holger; Cavalleri, Gianpiero L.; Delanty, Norman

in Epilepsia Open (2019), 0(0),

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See detailA Recurrent Missense Variant in AP2M1 Impairs Clathrin-Mediated Endocytosis and Causes Developmental and Epileptic Encephalopathy.
Helbig, Ingo; Lopez-Hernandez, Tania; Shor, Oded; Galer, Peter; Ganesan, Shiva; Pendziwiat, Manuela; Rademacher, Annika; Ellis, Colin A.; Humpfer, Nadja; Schwarz, Niklas; Seiffert, Simone; Peeden, Joseph; Shen, Joseph; Sterbova, Katalin; Hammer, Trine Bjorg; Moller, Rikke S.; Shinde, Deepali N.; Tang, Sha; Smith, Lacey; Poduri, Annapurna; Krause, Roland; Benninger, Felix; Helbig, Katherine L.; Haucke, Volker; Weber, Yvonne G.; EuroEPINOMICS-RES Consortium; Balling, Rudi; May, Patrick; GRIN consortium

in American journal of human genetics (2019)

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See detailIntestinal-Cell Kinase and Juvenile Myoclonic Epilepsy.
Lerche, Holger; Berkovic, Sam F.; Lowenstein, Daniel H.; EuroEPINOMICS-CoGIE; May, Patrick; Bobbili, Dheeraj Reddy; Krause, Roland; Balling, Rudi; EpiPGX consortium; Peter, Sarah; Epi4K Consortium/Epilepsy Phenome/Genome

in New England Journal of Medicine (2019), 380(16), 24

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See detailComparative effectiveness of antiepileptic drugs in juvenile myoclonic epilepsy
Silvennoinen, Katri; de Lange, Nikola Maria; Zagaglia, Sara; Balestrini, Simona; Androsova, Ganna; Wassenaar, Merel; Auce, Pauls; Avbersek, Andreja; Becker, Felicitas; Berghuis, Bianca; Campbell, Ellen; Coppola, Antonietta; Francis, Ben; Wolking, Stefan; Cavalleri, Gianpiero L.; Craig, John; Delanty, Norman; Johnson, Michael R.; Koeleman, Bobby P. C.; Kunz, Wolfram S.; Lerche, Holger; Marson, Anthony G.; O’Brien, Terence J.; Sander, Josemir W.; Sills, Graeme J.; Striano, Pasquale; Zara, Federico; van der Palen, Job; Krause, Roland; Depondt, Chantal; Sisodiya, Sanjay M.; Consortium, The Epipgx

in Epilepsia Open (2019), 0(0),

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2018

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See detailExome-wide analysis of mutational burden in patients with typical and atypical Rolandic Epilepsy
Bobbili, Dheeraj Reddy; Lal, Dennis; May, Patrick; Reinthaler, Eva M.; Jabbari, Kamel; Thiele, Holger; Nothnagel, Michael; Jurkowski, Wiktor; EuroEPINOMICS COGIE Consortium; Balling, Rudi; Feucht, Martha; Nürnberg, Peter; Lerche, Holger; Zimprich, Fritz; Krause, Roland; Neubauer, Bernd A.

in European Journal of Human Genetics (2018)

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See detailRare gene deletions in genetic generalized and Rolandic epilepsies
Jabbari, Kamel; Bobbili, Dheeraj Reddy; Lal, Dennis; Reinthaler, Eva M.; Schubert, Julian; Wolking, Stefan; Sinha, Vishai; Motameny, Susanne; Thiele, Holger; Kawalla, Amit; Altmüller, Janine; Toliat, Mohammed Reza; Kraaij, Robert; van Rooij, Jeroen; Uitterlinden, André G.; Ikram, M. Arfam; EuroEPINOMICS CoGIE Consortium; Balling, Rudi; Zara, Federico; Lehesjoki, Anna-Elina; Krause, Roland; Zimprich, Fritz; Sander, Thomas; Neubauer, Bernd A.; May, Patrick; Lerche, Holger; Nürnberg, Peter

in PLoS ONE (2018)

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See detailRare coding variants in genes encoding GABAA receptors in genetic generalised epilepsies: an exome-based case-control study
May, Patrick; Girard, Simon; Harrer, Merle; Bobbili, Dheeraj Reddy; Schubert, Julian; Wolking, Stefan; Becker, Felicitas; Lachance-Touchette, Pamela; Meloche, Caroline; Gravel, Micheline; Niturad, Christina E.; Knaus, Julia; De Kovel, Carolien; Toliat, Mohamad; Polvi, Anne; Iacomino, Michele; Guerrero-López, Rosa; Baulac, Stéphanie; Marini, Carla; Thiele, Holger; Altmüller, Janine; Jabbari, Kamel; Ruppert, Ann-Kathrin; Jurkowski, Wiktor; Lal, Dennis; Rusconi, Raffaella; Cestèle, Sandrine; Terragni, Benedetta; Coombs, Ian D.; Reid, Christopher A.; Striano, Pasquale; Caglayan, Hande; Siren, Auli; Everett, Kate; Møller, Rikke S.; Hjalgrim, Hille; Muhle, Hiltrud; Helbig, Ingo; Kunz, Wolfram S.; Weber, Yvonne G.; De Jonghe, Peter; Sisodiya, Sanjay M.; Nabbout, Rima; Franceschetti, Silvana; Coppola, Antonietta; Vari, Maria S.; Kasteleijn-Nolst Trenité, Dorothée; Baykan, Betul; Ozbek, Ugur; Bebek, Nerses; Klein, Karl M.; Rosenow, Felix; Nguyen, Dang K.; Dubeau, Francis; Carmant, Lionel; Lortie, Anne; Desbiens, Richard; Clément, Jean-François; Cieuta-Walti; Sills, Graeme J.; Auce, Pauls; Francin, Ben; Johnson, Michael R.; Berghuis, Bianca; Sander, Josemir W.; Avbersek, Andreja; McCormack, Mark; Cavalleri, Gianpiero L.; Delanty, Norman; Depondt, Chantal; Krenn, Martin; Zimprich, Fritz; Peter, Sarah; Nikanorova, Marina; Kraaij, Robert; van Rooij, Jeroen; Balling, Rudi; Ikram, M. Arfan; Uitterlinden, André G.; Avanzini, Giuliano; Schorge, Stephanie; Petrou, Steven; Mantegazza, Massimo; Sander, Thomas; LeGuern, Eric; Serratosa Jose M.; Koeleman, Bobby P.C.; Palotie, Aarno; Lehesjoki, Anna-Elina; Nothnagel, Michael; Nürnberg, Peter; Maljevic, Snezana; Zara, Federico; Cossette, Patrick; Krause, Roland; Lerche, Holger

in Lancet Neurology (2018), 17(8), 699-708

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See detailGenome-wide mega-analysis identifies 16 loci and highlights diverse biological mechanisms in the common epilepsies
The International League Against Epilepsy Consortium on Complex Epilepsies; Krause, Roland

in Nature Communications (2018)

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See detailPersonalized risk prediction of postoperative cognitive impairment - rationale for the EU-funded BioCog project.
Winterer, G.; Androsova, Ganna; Bender, O.; Boraschi, D.; Borchers, F.; Dschietzig, T. B.; Feinkohl, I.; Fletcher, P.; Gallinat, J.; Hadzidiakos, D.; Haynes, J. D.; Heppner, F.; Hetzer, S.; Hendrikse, J.; Ittermann, B.; Kant, I. M. J.; Kraft, A.; Krannich, A.; Krause, Roland; Kuhn, S.; Lachmann, G.; van Montfort, S. J. T.; Muller, A.; Nurnberg, P.; Ofosu, K.; Pietsch, M.; Pischon, T.; Preller, J.; Renzulli, E.; Scheurer, K.; Schneider, Reinhard; Slooter, A. J. C.; Spies, C.; Stamatakis, E.; Volk, H. D.; Weber, S.; Wolf, A.; Yurek, F.; Zacharias, N.

in European Psychiatry (2018), 50

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2017

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See detailApplication of rare variant transmission disequilibrium tests to epileptic encephalopathy trio sequence data
Allen, Andrew S.; Berkovic, Samuel F.; Bridgers, Joshua; Cossette, Patrick; Dlugos, Dennis; Epstein, Michael P.; Glauser, Tracy; Goldstein, David B.; Heinzen, Erin L.; Jiang, Yu; Johnson, Michael R.; Kuzniecky, Ruben; Lowenstein, Daniel H.; Marson, Anthony G.; Mefford, Heather C.; O'Brien, Terence J.; Ottman, Ruth; Petrou, Steven; Petrovski, Slavé; Poduri, Annapurna; Ren, Zhong; Scheffer, Ingrid E.; Sherr, Elliott; Wang, Quanli; Balling, Rudi; Barisic, Nina; Baulac, Stéphanie; Caglayan, Hande; Craiu, Dana; De Jonghe, Peter; Depienne, Christel; Guerrini, Renzo; Helbig, Ingo; Hjalgrim, Helle; Hoffman-Zacharska, Dorota; Jähn, Johanna; Klein, Karl Martin; Koeleman, Bobby; Komarek, Vladimir; Krause, Roland; Leguern, Eric; Lehesjoki, Anna-Elina; Lemke, Johannes R.; Lerche, Holger; Linnankivi, Tarja; Marini, Carla; May, Patrick; Møller, Rikke S.; Muhle, Hiltrud; Pal, Deb; Palotie, Aarno; Rosenow, Felix; Selmer, Kaja; Serratosa, Jose M.; Sisodiya, Sanjay; Stephani, Ulrich; Sterbova, Katalin; Striano, Pasquale; Suls, Arvid; Talvik, Tiina; von Spiczak, Sarah; Weber, Yvonne; Weckhuysen, Sarah; Zara, Federico; Abou-Khalil, Bassel; Alldredge, Brian K.; Amrom, Dina; Andermann, Eva; Andermann, Frederick; Bautista, Jocelyn F.; Berkovic, Samuel F.; Bluvstein, Judith; Cascino, Gregory D.; Consalvo, Damian; Crumrine, Patricia; Devinsky, Orrin; Dlugos, Dennis; Epstein, Michael P.; Fiol, Miguel E.; Fountain, Nathan B.; French, Jacqueline; Friedman, Daniel; Glauser, Tracy; Haas, Kevin; Haut, Sheryl R.; Hayward, Jean; Joshi, Sucheta; Kanner, Andres; Kirsch, Heidi E.; Kossoff, Eric H.; Kuperman, Rachel; Kuzniecky, Ruben; Lowenstein, Daniel H.; McGuire, Shannon M.; Motika, Paul V.; Novotny, Edward J.; Ottman, Ruth; Paolicchi, Juliann M.; Parent, Jack; Park, Kristen; Poduri, Annapurna; Scheffer, Ingrid E.; Shellhaas, Renée A.; Sherr, Elliott; Sirven, Joseph; Smith, Michael C.; Sullivan, Joseph; Thio, Liu Lin; Venkat, Anu; Vining, Eileen P. G.; Von Allmen, Gretchen K.; Weisenberg, Judith L.; Widdess-Walsh, Peter; Winawer, Melodie R.

in European Journal of Human Genetics (2017)

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See detailComparative effectiveness of antiepileptic drugs in patients with mesial temporal lobe epilepsy with hippocampal sclerosis
Androsova, Ganna; Krause, Roland; Borghei, Mojgansadat; Wassenaar, Merel; Auce, Pauls; Avbersek, Andreja; Becker, Felicitas; Berghuis, Bianca; Campbell, Ellen; Coppola, Antonietta; Francis, Ben; Wolking, Stefan; Cavalleri, Gianpiero L.; Craig, John; Delanty, Norman; Koeleman, Bobby P. C.; Kunz, Wolfram S.; Lerche, Holger; Marson, Anthony G.; Sander, Josemir W.; Sills, Graeme J.; Striano, Pasquale; Zara, Federico; Sisodiya, Sanjay M.; Depondt, Chantal; the EpiPGX Consortium

in Epilepsia (2017)

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See detailDe Novo Mutations in Synaptic Transmission Genes Including DNM1 Cause Epileptic Encephalopathies.
Appenzeller, Silke; Balling, Rudi; Barisic, Nina; Baulac, Stéphanie; Caglayan, Hande; Craiu, Dana; Jonghe, Peter De; Depienne, Christel; Dimova, Petia; Djémié, Tania; Gormley, Padhraig; Guerrini, Renzo; Helbig, Ingo; Hjalgrim, Helle; Hoffman-Zacharska, Dorota; Jähn, Johanna; Klein, Karl Martin; Koeleman, Bobby; Komarek, Vladimir; Krause, Roland; Kuhlenbäumer, Gregor; Leguern, Eric; Lehesjoki, Anna-Elina; Lemke, Johannes R.; Lerche, Holger; Linnankivi, Tarja; Marini, Carla; May, Patrick; Møller, Rikke S.; Muhle, Hiltrud; Pal, Deb; Palotie, Aarno; Pendziwiat, Manuela; Robbiano, Angela; Roelens, Filip; Rosenow, Felix; Selmer, Kaja; Serratosa, Jose M.; Sisodiya, Sanjay; Stephani, Ulrich; Sterbova, Katalin; Striano, Pasquale; Suls, Arvid; Talvik, Tiina; Spiczak, Sarah Von; Weber, Yvonne; Weckhuysen, Sarah; Zara, Federico; Abou-Khalil, Bassel; Alldredge, Brian K.; Andermann, Eva; Andermann, Frederick; Amrom, Dina; Bautista, Jocelyn F.; Berkovic, Samuel F.; Bluvstein, Judith; Boro, Alex; Cascino, Gregory; Consalvo, Damian; Crumrine, Patricia; Devinsky, Orrin; Dlugos, Dennis; Epstein, Michael P.; Fiol, Miguel; Fountain, Nathan B.; French, Jacqueline; Friedman, Daniel; Geller, Eric B.; Glauser, Tracy; Glynn, Simon; Haas, Kevin; Haut, Sheryl R.; Hayward, Jean; Helmers, Sandra L.; Joshi, Sucheta; Kanner, Andres; Kirsch, Heidi E.; Knowlton, Robert C.; Kossoff, Eric H.; Kuperman, Rachel; Kuzniecky, Ruben; Lowenstein, Daniel H.; McGuire, Shannon M.; Motika, Paul V.; Novotny, Edward J.; Ottman, Ruth; Paolicchi, Juliann M.; Parent, Jack; Park, Kristen; Poduri, Annapurna; Sadleir, Lynette; Scheffer, Ingrid E.; Shellhaas, Renée A.; Sherr, Elliott; Shih, Jerry J.; Singh, Rani; Sirven, Joseph; Smith, Michael C.; Sullivan, Joe; Thio, Liu Lin; Venkat, Anu; Vining, Eileen P. G.; Allmen, Gretchen K. Von; Weisenberg, Judith L.; Widdess-Walsh, Peter; Winawer, Melodie R.; Allen, Andrew S.; Berkovic, Samuel F.; Cossette, Patrick; Delanty, Norman; Dlugos, Dennis; Eichler, Evan E.; Epstein, Michael P.; Glauser, Tracy; Goldstein, David B.; Han, Yujun; Heinzen, Erin L.; Johnson, Michael R.; Kuzniecky, Ruben; Lowenstein, Daniel H.; Marson, Anthony G.; Mefford, Heather C.; Nieh, Sahar Esmaeeli; O’Brien, Terence J.; Ottman, Ruth; Petrou, Stephen; Petrovski, Slavé; Poduri, Annapurna; Ruzzo, Elizabeth K.; Scheffer, Ingrid E.; Sherr, Elliott

in American Journal of Human Genetics (2017), 100(1), 179-

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See detailA systems level analysis of epileptogenesis-associated proteome alterations.
Keck, Michael; Androsova, Ganna; Gualtieri, Fabio; Walker, Andreas; von Ruden, Eva-Lotta; Russmann, Vera; Deeg, Cornelia A.; Hauck, Stefanie M.; Krause, Roland; Potschka, Heidrun

in Neurobiology of disease (2017), 105

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See detailGenetic variation in CFH predicts phenytoin-induced maculopapular exanthema in European-descent patients.
McCormack, Mark; Gui, Hongsheng; Ingason, Andres; Speed, Doug; Wright, Galen E. B.; Zhang, Eunice J.; Secolin, Rodrigo; Yasuda, Clarissa; Kwok, Maxwell; Wolking, Stefan; Becker, Felicitas; Rau, Sarah; Avbersek, Andreja; Heggeli, Kristin; Leu, Costin; Depondt, Chantal; Sills, Graeme J.; Marson, Anthony G.; Auce, Pauls; Brodie, Martin J.; Francis, Ben; Johnson, Michael R.; Koeleman, Bobby P. C.; Striano, Pasquale; Coppola, Antonietta; Zara, Federico; Kunz, Wolfram S.; Sander, Josemir W.; Lerche, Holger; Klein, Karl Martin; Weckhuysen, Sarah; Krenn, Martin; Gudmundsson, Larus J.; Stefansson, Kari; Krause, Roland; Shear, Neil; Ross, Colin J. D.; Delanty, Norman; Pirmohamed, Munir; Carleton, Bruce C.; Cendes, Fernando; Lopes-Cendes, Iscia; Liao, Wei-Ping; O'Brien, Terence J.; Sisodiya, Sanjay M.; Cherny, Stacey; Kwan, Patrick; Baum, Larry; Cavalleri, Gianpiero L.

in Neurology (2017)

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See detailRare GABRA3 variants are associated with epileptic seizures, encephalopathy and dysmorphic features
Niturad, Elena Christina; Lev, Dorit; Kalscheuer, Vera M; Charzewska, Agnieszka; Schubert, Julian; Lerman-Sagie, Tally; Kroes, Hester Y; Oegema, Renske; Traverso, Monica; Specchio, Nicola; Lassota, Maria; Chelly, Jamel; Bennett-Back, Odeya; Carmi, Nirit; Koffler-Brill, Tal; Iacomino, Michele; Trivisano, Marina; Capovilla, Giuseppe; Striano, Pasquale; Nawara, Magdalena; Rzonca, Sylwia; Fischer, Ute; Bienek, Melanie; Jensen, Corinna; Hu, Hao; Thiele, Holger; Altmüller, Janine; Krause, Roland; May, Patrick; Becker, Felicitas; EuroEPINOMICS Consortium; Balling, Rudi; Biskup, Saskia; Haas, Stefan A; Nürnberg, Peter; van Gassen, Koen L I; Lerche, Holger; Zara, Federico; Maljevic, Snezana; Leshinsky-Silver, Esther

in Brain : A Journal of Neurology (2017), 140(11), 2879-2894

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See detailAlterations in the α2δ ligand, thrombospondin-1, in a rat model of spontaneous absence epilepsy and in patients with idiopathic/genetic generalized epilepsies
Santolini, Ines; Celli, Roberta; Cannella, Milena; Imbriglio, Tiziana; Guiducci, Michela; Parisi, Pasquale; Schubert, Julian; Iacomino, Michele; Zara, Federico; Lerche, Holger; EuroEPINOMICS CoGIE Consortium; May, Patrick; Krause, Roland; Balling, Rudi; Genetic Commission of Italian League Against Epilepsy (LICE); Moyanova, Slavianka; Ngomba, Richard Teke; van Luijtellar, Gilles; Battaglia, Giuseppe; Bruno, Valeria; Striano, Pasquale; Nicoletti, Ferdinando

in Epilepsia (2017)

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2016

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See detailCrowdsourced estimation of cognitive decline and resilience in Alzheimer's disease
Allen, Genevera; Amoroso, Nicola; Anghel, Catalina; Balagurusamy, Venkat; Bare, Christopher; Beaton, Derek; Bellotti, Roberto; Bennett, David; Boehme, Kevin; Caberlotto, Laura; Campbell, Frederick; Chang, Yu-Chuan; Chen, Beibei; Chen, Chien-Yu; Chien, Ting-Ying; Clark, Tim; Das, Sudeshna; Davatzikos, Christos; Deng, Jieyao; Dillenberger, Donna; Dobson, Richard; Dong, Qilin; Doshi, Jimit; Duma, Denise; Errico, Rosangela; Erus, Guray; Everett, Evan; Fardo, David; Friend, Stephen; Fröhlich, Holger; Gan, Jessica; St George-Hyslop, Peter; Ghosh, Satrajit; Glaab, Enrico; Green, Robert; Guan, Yuanfang; Hong, Ming-Yi; Huang, Chao; Hwang, Jinseub; Ibrahim, Joseph; Inglese, Paolo; Jiang, Qijia; Katsumata, Yurik; Kauwe, Jo; Klein, Arno; Kong, Dehan; Krause, Roland; Lalonde, Emilie; Lauria, Mari; Lee, Eunjee; Lin, Xihui; Liu, Zhandong; Livingstone, Julie; Logsdon, Benjami; Lovestone, Simon; Iyappan, Anandhi; Ma, Tsung-wei; Malhotra, Ashutos; Maxwell, Taylor; Merrill, Emily; Nagorski, John; Alex Namasivayam, Aishwarya; Narayan, Manjari; Naz, Mufassra; Neto, Elias Chaibub; Newhouse, Stephen; Norman, Thea; Nurtdinov, Ramil; Oyang, Yen-Jen; Boutros, Paul; Pawitan, Yudi; Peng, Shengwen; Peters, Mette; Piccolo, Stephen; Praveen, Paurush; Priami, Corrado; Sabelnykova, Veronica; Senger, Philipp; Shen, Xia; Simmons, Andrew; Sotiras, Aristeidis; Stolovitzky, Gustavo; Tangaro, Sabina; Tateo, Andrea; Tung, Yi-An; Tustison, Nicholas; Varol, Erdem; Vradenburg, George; Weiner, Michael; Xiao, Guanghua; Xie, Lei; Xie, Yang; Xu, Jia; Yang, Hojin; Zhan, Xiaowei; Zhou, Yunyun; Zhu, Fan; Zhu, Hongtu; Zhu, Shanfeng; Alzheimer's Disease Neuroimaging Initiative

in Alzheimer's and Dementia: the Journal of the Alzheimer's Association (2016), 12(6), 645-653

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See detailThe Human Phenotype Ontology in 2017
Köhler, Sebastian; Vasilevsky, Nicole A.; Engelstad, Mark; Foster, Erin; McMurry, Julie; Aymé, Ségolène; Baynam, Gareth; Bello, Susan M.; Boerkoel, Cornelius F.; Boycott, Kym M.; Brudno, Michael; Buske, Orion J.; Chinnery, Patrick F.; Cipriani, Valentina; Connell, Laureen E.; Dawkins, Hugh J. S.; DeMare, Laura E.; Devereau, Andrew D.; de Vries, Bert B. A.; Firth, Helen V.; Freson, Kathleen; Greene, Daniel; Hamosh, Ada; Helbig, Ingo; Hum, Courtney; Jähn, Johanna A.; James, Roger; Krause, Roland; Laulederkind, Stanley J. F.; Lochmüller, Hanns; Lyon, Gholson J.; Ogishima, Soichi; Olry, Annie; Ouwehand, Willem H.; Pontikos, Nikolas; Rath, Ana; Schaefer, Franz; Scott, Richard H.; Segal, Michael; Sergouniotis, Panagiotis I.; Sever, Richard; Smith, Cynthia L.; Straub, Volker; Thompson, Rachel; Turner, Catherine; Turro, Ernest; Veltman, Marijcke W. M.; Vulliamy, Tom; Yu, Jing; von Ziegenweidt, Julie; Zankl, Andreas; Züchner, Stephan; Zemojtel, Tomasz; Jacobsen, Julius O. B.; Groza, Tudor; Smedley, Damian; Mungall, Christopher J.; Haendel, Melissa; Robinson, Peter N.

in Nucleic Acids Research (2016)

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See detailEvaluation of Presumably Disease Causing SCN1A Variants in a Cohort of Common Epilepsy Syndromes
Lal, Dennis; Reinthaler, Eva; Dejanovic; May, Patrick; Thiele, Holger; Lehesjoki, Anna-Elina; Schwarz, Guenter; Riesch, Erik; Ikram, Arfan; van Duijn, Cornelia; Uitterlinden, Andre; Steinböck, Hannelore; Gruber-Sedlmayr, Ursula; Neophytou, Birgit; Zara, Frederico; Hahn, Andreas; Genetic Commission of the Italian League against Epilepsy; EuroEPINOMICS CoGIE Consortium; Balling, Rudi; Becker, Felicitas; Weber, Yvonne; Cilio, Maria Roberta; Kunz, Wolfram; Krause, Roland; Zimprich, Fritz; Lemke, Johannes R.; Nürnberg, Peter; Sander, Thomas; Lerche, Holger; Neubauer, Bernd

in PLoS ONE (2016)

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See detail70S-scanning initiation is a novel and frequent initiation mode of ribosomal translation in bacteria.
Yamamoto, Hiroshi; Wittek, Daniela; Gupta, Romi; Qin, Bo; Ueda, Takuya; Krause, Roland; Yamamoto, Kaori; Albrecht, Renate; Pech, Markus; Nierhaus, Knud H.

in Proceedings of the National Academy of Sciences of the United States of America (2016), 113(9), 1180-9

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2015

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See detailBiomarkers of postoperative delirium and cognitive dysfunction
Androsova, Ganna; Krause, Roland; Winterer, Georg; Schneider, Reinhard

in Frontiers in Aging Neuroscience (2015), 7(112),

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See detailCHD2 variants are a risk factor for photosensitivity in epilepsy
Galizia, Elizabeth C.; Myers, Candace T.; Leu, Costin; de Kovel, Carolien G. F.; Afrikanova, Tatiana; Cordero-Maldonado, Maria Lorena; Martins, Teresa; Jacmin, Maxime; Drury, Suzanne; Krishna Chinthapalli, V.; Muhle, Hiltrud; Pendziwiat, Manuela; Sander, Thomas; Ruppert, Ann-Kathrin; Møller, Rikke S.; Thiele, Holger; Krause, Roland; Schubert, Julian; Lehesjoki, Anna-Elina; Nürnberg, Peter; Lerche, Holger; Palotie, Aarno; Coppola, Antonietta; Striano, Salvatore; Gaudio, Luigi Del; Boustred, Christopher; Schneider, Amy L.; Lench, Nicholas; Jocic-Jakubi, Bosanka; Covanis, Athanasios; Capovilla, Giuseppe; Veggotti, Pierangelo; Piccioli, Marta; Parisi, Pasquale; Cantonetti, Laura; Sadleir, Lynette G.; Mullen, Saul A.; Berkovic, Samuel F.; Stephani, Ulrich; Helbig, Ingo; Crawford, Alexander Dettmar; Esguerra, Camila V.; Kasteleijn-Nolst Trenité, Dorothee G. A.; Koeleman, Bobby P. C.; Mefford, Heather C.; Scheffer, Ingrid E.; Sisodiya, Sanjay M.

in Brain: a Journal of Neurology (2015)

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See detailInvestigation of GRIN2A in common epilepsy phenotypes.
Lal, Dennis; Steinbrucker, Sandra; Schubert, Julian; Sander, Thomas; Becker, Felicitas; Weber, Yvonne; Lerche, Holger; Thiele, Holger; Krause, Roland; Lehesjoki, Anna-Elina; Nurnberg, Peter; Palotie, Aarno; Neubauer, Bernd A.; Muhle, Hiltrud; Stephani, Ulrich; Helbig, Ingo; Becker, Albert J.; Schoch, Susanne; Hansen, Jorg; Dorn, Thomas; Hohl, Christin; Luscher, Nicole; von Spiczak, Sarah; Lemke, Johannes R.

in Epilepsy research (2015), 115

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See detailThe phenotypic spectrum of SCN8A encephalopathy
Larsen, Jan; Carvill, Gemma L.; Gardella, Elena; Kluger, Gerhard; Schmiedel, Gudrun; Barisic, Nina; Depienne, Christel; Brilstra, Eva; Mang, Yuan; Nielsen, Jens E.K.; Kirkpatrick, Martin; Goudie, David; Goldman, Rebecca; Jähn, Johanna A.; Jepsen, Birgit; Gill, Deepak; Döcker, Miriam; Biskup, Saskia; McMahon, Jacinta M.; Koeleman, Bobby; Harris, Mandy; Braun, Kees; de Kovel, Carolien G.F.; Marini, Carla; Specchio, Nicola; Djémié, Tania; Weckhuysen, Sarah; Krause, Roland; May, Patrick; Balling, Rudi; Tommerup, Niels; Troncoso, Monica; Troncoso, Ledia; Bevot, Andrea; Wolff, Markus; Hjalgrim, Helle; Guerrini, Renzo; Scheffer, Ingrid E.; Mefford, Heather C.; Møller, Rikke S.; EuroEPINOMICS RES Consortium CRP

in Neurology (2015), 84(5), 480-489

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See detailDe novo loss- or gain-of-function mutations in KCNA2 cause epileptic encephalopathy
Syrbe, Steffen; Hedrich, Ulrike B.S.; Riesch, Erik; Djémié, Tanja; Müller, Stephan; Møller, Rikke S.; Maher, Bridget; Hernandez-Hernandez, Laura; Synofzik, Matthis; Caglayan, Hande S.; Arslan, Mutluay; Serratosa, José M.; Nothnagel, Michael; May, Patrick; Krause, Roland; Löffler, Heidrun; Detert, Katja; Dorn, Thomas; Vogt, Heinrich; Krämer, Günter; Schöls, Ludger; Mullis, Primus E.; Linnankivi, Tarja; Lehesjoki, Anna-Elina; Sterbova, Katalin; Craiu, Dana C.; Hoffman-Zacharska, Dorota; Korff, Christian M.; Weber, Yvonne G.; Steinlin, Maja; Gallati, Sabina; Bertsche, Astrid; Bernhard, Matthias K.; Merkenschlager, Andreas; Kiess, Wieland; EUROEPINOMICS RES consortium; Balling, Rudi; Gonzalez, Michael; Züchner, Stefan; Palotie, Aarno; Suls, Arvid; De Jonghe, Peter; Helbig, Ingo; Biskup, Saskia; Wolff, Markus; Maljeviv, Snezana; Schüle, Rebecca; Sisodoya, Sanjay M.; Weckhuysen, Sarah; Lerche, Holger; Lemke, Johannes R.

in Nature Genetics (2015), 47(4), 393-9

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See detailCHD2 myoclonic encephalopathy is frequently associated with self-induced seizures
Thomas, Rhys H.; Zhang, Lin Mei; Carvill, Gemma L.; Archer, John S.; Heavin, Sinéad B.; Mandelstam, Simone A.; Craiu, Dana; Berkovic, Samuel F.; Gill, Deepak S.; Mefford, Heather C.; Scheffer, Ingrid E.; Paalotie, Aarno; Lehesjoki, Anna-Elina; Koeleman, Bobby; Marini, Carla; Depienne, Christel; Pal, Deb; Hoffman-Zacharska, Dorota; Leguern, Eric; Zara, Federico; Rosenow, Felix; Caglayan, Hande; Hjalgrim, Helle; Muhle, Hiltrud; Lerche, Holger; Helbig, Ingo; Jähn, Johanna; Lemke, Johannes; Serratosa, Jose M.; Selmer, Katja; Klein, Karl Martin; Sterbova, Katalin; Pendziwiat, Manuela; Barisic, Nina; Gormley, Padhraig; Striano, Pasquale; May, Patrick; De Jonghe, Peter; Guerrini, Renzo; Møller, Rikke S.; Krause, Roland; Balling, Rudi; Sisodiya, Sanjay; von Spiczak, Sarah; Weckhuysen, Sarah; Baulac, Stéphanie; Suls, Arvid; Djemie, Tania; Stephani, Ulrich; Komarek, Vladimir; Weber, Yvonne

in Neurology (2015), 84(9), 951-958

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2014

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See detailDe Novo Mutations in Synaptic Transmission Genes Including DNM1 Cause Epileptic Encephalopathies
Appenzeller, Silke; Balling, Rudi; Barisic, Nina; Baulac, Stephanie; Caglayan, Hande; Craiu, Dana; De Jonghe, Peter; Depienne, Christel; Dimova, Petia; Djemie, Tania; Gormly, Padhraig; Guerrini, Renzo; Helbig, Ingo; Hjalgrim, Helle; Hoffman-Zacharska, Dorota; Jähn; Klein, Karl Martin; Koeleman, Bobby; Komarek, Vladimir; Krause, Roland; Kuhlenbäumer, Gregor; Leguern, Eric; Lehesjoki, Anna-Elina; Lemke, Johannes R.; Lerche, Holger; Linnankivi, Tarja; Marini, Carla; May, Patrick; Møller, Rikke S.; Muhle, Hiltrud; Pal, Deb; Palotie, Aarno; Pendziwitat, Manuela; Robbiano, Angela; Roelens, Filip; Rosenow, Felix; Selmer, Kaja; Serratosa, Jose M.; Sisodiya, Sanjay; Stephani, Ulrich; Sterbova, Katalin; Striano, Pasquale; Suls, Arvid; Talvik, Tiina; von Spizak, Sarah; Weber, Yvonne; Weckhuysen, Sarah; Zara, Frederico; Epilepsy Phenome/Genome Project; Epi4K Consortium

in American Journal of Human Genetics (2014), 4

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See detailDe novo mutations in HCN1 cause early infantile epileptic encephalopathy
Nava, Caroline; Dalle, Carine; Rastetter, Agnès; Striano, Pasquale; de Kovel, Carolien G. F.; Nabbout, Rima; Cancès, Claude; Ville, Dorothée; Brilstra, Eva H.; Gobbi, Giuseppe; Raffo, Emmanuel; Bouteiller, Delphine; Marie, Yannick; Trouillard, Oriane; Robbiano, Angela; Keren, Boris; Agher, Dahbia; Roze, Emmanuel; Lesage, Suzanne; Nicolas, Aude; Brice, Alexis; Baulac, Michel; Vogt, Cornelia; El Hajj, Nady; Schneider, Eberhard; Suls, Arvid; Weckhuysen, Sarah; Gormley, Padhraig; Lehesjoki, Anna-Elina; De Jonghe, Peter; Helbig, Ingo; Baulac, Stephanie; Zara, Federico; Koeleman, Bobby P. C.; Consortium, Euroepinomics R. E. S.; Haaf, Thomas; LeGuern, Eric; Depienne, Christel; May, Patrick; Balling, Rudi; Barisic, Nina; Baulac, Stéphanie; Caglayan, Hande S.; Craiu, Dana C.; De Jonghe, Peter; Depienne, Christel; Gormley, Padhraig; Guerrini, Renzo; Helbig, Ingo; Hjalgrim, Helle; Hoffman-Zacharska, Dorota; Jähn, Johanna; Klein, Karl Martin; Koeleman, Bobby P. C.; Komarek, Vladimir; Krause, Roland; LeGuern, Eric; Lehesjoki, Anna-Elina; Lemke, Johannes R.; Lerche, Holger; Marini, Carla; Møller, Rikke S.; Muhle, Hiltrud; Palotie, Aarno; Pal, Deb; Rosenow, Felix; Selmer, Kaja; Serratosa, José M.; Sisodiya, Sanjay; Stephani, Ulrich; Sterbova, Katalin; Striano, Pasquale; Suls, Arvid; Talvik, Tiina; von Spiczak, Sarah; Weber, Yvonne; Weckhuysen, Sarah; Zara, Federico

in Nature Genetics (2014)

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See detailMutations in STX1B, encoding a presynaptic protein, cause fever-associated epilepsy syndromes
Schubert, Julian; Siekierska, Aleksandra; Langlois, Melanie; May, Patrick; Huneau, Clement; Becker, Felicitas; Muhle, Hiltrud; Suls, Arvid; Lemke, Johannes R.; de Kovel, Carolien G. F.; Thiele, Holger; Konrad, Kathryn; Kawalia, Amit; Toliat, Mohammad R.; Sander, Thomas; Ruschendorf, Franz; Caliebe, Almuth; Nagel, Inga; Kohl, Bernard; Kecskes, Angela; Jacmin, Maxime; Hardies, Katia; Weckhuysen, Sarah; Riesch, Erik; Dorn, Thomas; Brilstra, Eva H.; Baulac, Stephanie; Moller, Rikke S.; Hjalgrim, Helle; Koeleman, Bobby P. C.; EuroEPINOMICS RES Consortium; Krause, Roland; Jurkat-Rott, Karin; Lehman-Horn, Frank; Roach, Jared C.; Glusman, Gustavo; Hood, Leroy; Galas, David J.; Martin, Benoit; de Witte, Peter A. M.; Biskup, Saskia; De Jonghe, Peter; Helbig, Ingo; Balling, Rudi; Nurnberg, Peter; Crawford, Alexander Dettmar; Esguerra, Camila V.; Weber, Yvonne G.; Lerche, Holger

in Nature Genetics (2014), 46(12), 1327-32

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2012

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See detailExploring biological interaction networks with tailored weighted quasi-bicliques.
Chang, Wen-Chieh; Vakati, Sudheer; Krause, Roland; Eulenstein, Oliver

in BMC Bioinformatics (2012), 13 Suppl 10

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2011

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See detailSelecting oligonucleotide probes for whole-genome tiling arrays with a cross-hybridization potential.
Hafemeister, Christoph; Krause, Roland; Schliep, Alexander

in IEEE/ACM Transactions on Computational Biology and Bioinformatics (2011), 8(6), 1642-52

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See detailCocos: Constructing multi-domain protein phylogenies.
Homilius, Max; Wiedenhoeft, John; Thieme, Sebastian; Standfuss, Christoph; Kel, Ivan; Krause, Roland

in PLoS Currents (2011), 3

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See detailThe plexus model for the inference of ancestral multidomain proteins.
Wiedenhoeft, John; Krause, Roland; Eulenstein, Oliver

in IEEE/ACM Transactions on Computational Biology and Bioinformatics (2011), 8(4), 890-901

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2010

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See detailLive Coverage of Intelligent Systems for Molecular Biology
Lister, Allyson L.; Datta, Ruchira S.; Hofmann, Oliver; Krause, Roland; Kuhn, Michael; Roth, Bettina; Schneider, Reinhard

in PLoS Computational Biology (2010), 6

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See detailLive Coverage of Scientific Conferences Using Web Technologies
Lister, Allyson L.; Datta, Ruchira S.; Hofmann, Oliver; Krause, Roland; Kuhn, Michael; Roth, Bettina; Schneider, Reinhard

in PLoS Computational Biology (2010), 6(1), 1-2

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2008

See detailMutation in the transcriptional regulator PhoP contributes to avirulence of Mycobacterium tuberculosis H37Ra strain.
Lee, Jong Seok; Krause, Roland; Schreiber, Jorg; Mollenkopf, Hans-Joachim; Kowall, Jane; Stein, Robert; Jeon, Bo-Young; Kwak, Jeong-Yeon; Song, Min-Kyong; Patron, Juan Pablo; Jorg, Sabine; Roh, Kyoungmin; Cho, Sang-Nae; Kaufmann, Stefan H. E.

in Cell Host and Microbe (2008), 3(2), 97-103

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2007

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See detailIdentifying protein complexes directly from high-throughput TAP data with Markov random fields.
Rungsarityotin, Wasinee; Krause, Roland; Schodl, Arno; Schliep, Alexander

in BMC Bioinformatics (2007), 8

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2006

See detailIdentifying protein complexes in high-throughput protein interaction screens using an infinite latent feature model.
Chu, Wei; Ghahramani, Zoubin; Krause, Roland; Wild, David L.

in Pacific Symposium on Biocomputing (2006)

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2004

See detailShared components of protein complexes--versatile building blocks or biochemical artefacts?
von Mering, Christian; Bork, Peer; Dandekar, Thomas; Krause, Roland

in BioEssays (2004), 26(12), 1333-43

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2003

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See detailA comprehensive set of protein complexes in yeast: mining large scale protein-protein interaction screens.
Krause, Roland; von Mering, Christian; Bork, Peer

in Bioinformatics (2003), 19(15), 1901-8

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2002

See detailFunctional organization of the yeast proteome by systematic analysis of protein complexes.
Gavin, Anne-Claude; Bosche, Markus; Krause, Roland; Grandi, Paola; Marzioch, Martina; Bauer, Andreas; Schultz, Jorg; Rick, Jens M.; Michon, Anne-Marie; Cruciat, Cristina-Maria; Remor, Marita; Hofert, Christian; Schelder, Malgorzata; Brajenovic, Miro; Ruffner, Heinz; Merino, Alejandro; Klein, Karin; Hudak, Manuela; Dickson, David; Rudi, Tatjana; Gnau, Volker; Bauch, Angela; Bastuck, Sonja; Huhse, Bettina; Leutwein, Christina; Heurtier, Marie-Anne; Copley, Richard R.; Edelmann, Angela; Querfurth, Erich; Rybin, Vladimir; Drewes, Gerard; Raida, Manfred; Bouwmeester, Tewis; Bork, Peer; Seraphin, Bertrand; Kuster, Bernhard; Neubauer, Gitte; Superti-Furga, Giulio

in Nature (2002), 415(6868), 141-7

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