Publications

In press

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See detailAbsence of regulator of G-protein signaling 4 does not protect against dopamine neuron dysfunction and injury in the mouse 6-hydroxydopamine lesion model of Parkinson's disease
Ashrafi, Amer; Garcia, Pierre; Kollmus, Heike; Schughart, Klaus; del Sol Mesa, Antonio; Buttini, Manuel; Glaab, Enrico

in Neurobiology of Aging (in press)

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See detailComputational systems biology approaches for Parkinson's disease
Glaab, Enrico

in Cell & Tissue Research (in press)

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See detailGender-specific expression of ubiquitin-specific peptidase 9 modulates tau expression and phosphorylation: possible implications for tauopathies
Köglsberger, Sandra; Cordero Maldonado, Maria Lorena; Antony, Paul; Forster, Julia; Garcia, Pierre; Buttini, Manuel; Crawford, Alexander Dettmar; Glaab, Enrico

in Molecular Neurobiology (in press)

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See detailToward Omics-Based, Systems Biomedicine, and Path and Drug Discovery Methodologies for Depression-Inflammation Research
Maes; Nowak, Gabriel; Caso, Javier; Leza, Juan Carlos; Song, Cai; Kubera, Marta; Klein, Hans; Galecki, Pjotr; Noto, Cristiano; Glaab, Enrico; Balling, Rudi; Berk, Michael

in Molecular Neurobiology (in press)

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2017

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See detailApplication of rare variant transmission disequilibrium tests to epileptic encephalopathy trio sequence data
Allen, Andrew S.; Berkovic, Samuel F.; Bridgers, Joshua; Cossette, Patrick; Dlugos, Dennis; Epstein, Michael P.; Glauser, Tracy; Goldstein, David B.; Heinzen, Erin L.; Jiang, Yu; Johnson, Michael R.; Kuzniecky, Ruben; Lowenstein, Daniel H.; Marson, Anthony G.; Mefford, Heather C.; O'Brien, Terence J.; Ottman, Ruth; Petrou, Steven; Petrovski, Slavé; Poduri, Annapurna; Ren, Zhong; Scheffer, Ingrid E.; Sherr, Elliott; Wang, Quanli; Balling, Rudi; Barisic, Nina; Baulac, Stéphanie; Caglayan, Hande; Craiu, Dana; De Jonghe, Peter; Depienne, Christel; Guerrini, Renzo; Helbig, Ingo; Hjalgrim, Helle; Hoffman-Zacharska, Dorota; Jähn, Johanna; Klein, Karl Martin; Koeleman, Bobby; Komarek, Vladimir; Krause, Roland; Leguern, Eric; Lehesjoki, Anna-Elina; Lemke, Johannes R.; Lerche, Holger; Linnankivi, Tarja; Marini, Carla; May, Patrick; Møller, Rikke S.; Muhle, Hiltrud; Pal, Deb; Palotie, Aarno; Rosenow, Felix; Selmer, Kaja; Serratosa, Jose M.; Sisodiya, Sanjay; Stephani, Ulrich; Sterbova, Katalin; Striano, Pasquale; Suls, Arvid; Talvik, Tiina; von Spiczak, Sarah; Weber, Yvonne; Weckhuysen, Sarah; Zara, Federico; Abou-Khalil, Bassel; Alldredge, Brian K.; Amrom, Dina; Andermann, Eva; Andermann, Frederick; Bautista, Jocelyn F.; Berkovic, Samuel F.; Bluvstein, Judith; Cascino, Gregory D.; Consalvo, Damian; Crumrine, Patricia; Devinsky, Orrin; Dlugos, Dennis; Epstein, Michael P.; Fiol, Miguel E.; Fountain, Nathan B.; French, Jacqueline; Friedman, Daniel; Glauser, Tracy; Haas, Kevin; Haut, Sheryl R.; Hayward, Jean; Joshi, Sucheta; Kanner, Andres; Kirsch, Heidi E.; Kossoff, Eric H.; Kuperman, Rachel; Kuzniecky, Ruben; Lowenstein, Daniel H.; McGuire, Shannon M.; Motika, Paul V.; Novotny, Edward J.; Ottman, Ruth; Paolicchi, Juliann M.; Parent, Jack; Park, Kristen; Poduri, Annapurna; Scheffer, Ingrid E.; Shellhaas, Renée A.; Sherr, Elliott; Sirven, Joseph; Smith, Michael C.; Sullivan, Joseph; Thio, Liu Lin; Venkat, Anu; Vining, Eileen P. G.; Von Allmen, Gretchen K.; Weisenberg, Judith L.; Widdess-Walsh, Peter; Winawer, Melodie R.

in European Journal of Human Genetics (2017)

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See detailComparative effectiveness of antiepileptic drugs in patients with mesial temporal lobe epilepsy with hippocampal sclerosis
Androsova, Ganna; Krause, Roland; Borghei, Mojgansadat; Wassenaar, Merel; Auce, Pauls; Avbersek, Andreja; Becker, Felicitas; Berghuis, Bianca; Campbell, Ellen; Coppola, Antonietta; Francis, Ben; Wolking, Stefan; Cavalleri, Gianpiero L.; Craig, John; Delanty, Norman; Koeleman, Bobby P. C.; Kunz, Wolfram S.; Lerche, Holger; Marson, Anthony G.; Sander, Josemir W.; Sills, Graeme J.; Striano, Pasquale; Zara, Federico; Sisodiya, Sanjay M.; Depondt, Chantal; the EpiPGX Consortium

in Epilepsia (2017)

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See detailDe Novo Mutations in Synaptic Transmission Genes Including DNM1 Cause Epileptic Encephalopathies.
Appenzeller, Silke; Balling, Rudi; Barisic, Nina; Baulac, Stéphanie; Caglayan, Hande; Craiu, Dana; Jonghe, Peter De; Depienne, Christel; Dimova, Petia; Djémié, Tania; Gormley, Padhraig; Guerrini, Renzo; Helbig, Ingo; Hjalgrim, Helle; Hoffman-Zacharska, Dorota; Jähn, Johanna; Klein, Karl Martin; Koeleman, Bobby; Komarek, Vladimir; Krause, Roland; Kuhlenbäumer, Gregor; Leguern, Eric; Lehesjoki, Anna-Elina; Lemke, Johannes R.; Lerche, Holger; Linnankivi, Tarja; Marini, Carla; May, Patrick; Møller, Rikke S.; Muhle, Hiltrud; Pal, Deb; Palotie, Aarno; Pendziwiat, Manuela; Robbiano, Angela; Roelens, Filip; Rosenow, Felix; Selmer, Kaja; Serratosa, Jose M.; Sisodiya, Sanjay; Stephani, Ulrich; Sterbova, Katalin; Striano, Pasquale; Suls, Arvid; Talvik, Tiina; Spiczak, Sarah Von; Weber, Yvonne; Weckhuysen, Sarah; Zara, Federico; Abou-Khalil, Bassel; Alldredge, Brian K.; Andermann, Eva; Andermann, Frederick; Amrom, Dina; Bautista, Jocelyn F.; Berkovic, Samuel F.; Bluvstein, Judith; Boro, Alex; Cascino, Gregory; Consalvo, Damian; Crumrine, Patricia; Devinsky, Orrin; Dlugos, Dennis; Epstein, Michael P.; Fiol, Miguel; Fountain, Nathan B.; French, Jacqueline; Friedman, Daniel; Geller, Eric B.; Glauser, Tracy; Glynn, Simon; Haas, Kevin; Haut, Sheryl R.; Hayward, Jean; Helmers, Sandra L.; Joshi, Sucheta; Kanner, Andres; Kirsch, Heidi E.; Knowlton, Robert C.; Kossoff, Eric H.; Kuperman, Rachel; Kuzniecky, Ruben; Lowenstein, Daniel H.; McGuire, Shannon M.; Motika, Paul V.; Novotny, Edward J.; Ottman, Ruth; Paolicchi, Juliann M.; Parent, Jack; Park, Kristen; Poduri, Annapurna; Sadleir, Lynette; Scheffer, Ingrid E.; Shellhaas, Renée A.; Sherr, Elliott; Shih, Jerry J.; Singh, Rani; Sirven, Joseph; Smith, Michael C.; Sullivan, Joe; Thio, Liu Lin; Venkat, Anu; Vining, Eileen P. G.; Allmen, Gretchen K. Von; Weisenberg, Judith L.; Widdess-Walsh, Peter; Winawer, Melodie R.; Allen, Andrew S.; Berkovic, Samuel F.; Cossette, Patrick; Delanty, Norman; Dlugos, Dennis; Eichler, Evan E.; Epstein, Michael P.; Glauser, Tracy; Goldstein, David B.; Han, Yujun; Heinzen, Erin L.; Johnson, Michael R.; Kuzniecky, Ruben; Lowenstein, Daniel H.; Marson, Anthony G.; Mefford, Heather C.; Nieh, Sahar Esmaeeli; O’Brien, Terence J.; Ottman, Ruth; Petrou, Stephen; Petrovski, Slavé; Poduri, Annapurna; Ruzzo, Elizabeth K.; Scheffer, Ingrid E.; Sherr, Elliott

in American Journal of Human Genetics (2017), 100(1), 179-

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See detailNeuroChip, an updated version of the NeuroX genotyping platform to rapidly screen for variants associated with neurological diseases
Blauwendraat, Cornelis; Faghri, Faraz; Pihlstrom, Lasse; Geiger, Joshua T.; Elbaz, Alexis; Lesage, Susanne; May, Patrick; Aude, Nicolas; Abramzon, Yevgeniya; Murphy, Natalie A.; Gibbs, J. Raphael; Ryten, Mina; Ferrari, Raffaele; Bras, Jose; Guerreiro, Rita; Williams, Julie; Sims, Rebecca; Lubbe, Steven; Hernandez, Dena G.; Mok, Kin Y.; Robak, Laurie; Camphell, Roy H.; Rogaeva, Ekaterina; Traynor, Bryan J.; Chia, Ruth; Chung, Sun Ju; International Parkinson’s Disease Genomics Consortium (IPDGC); COURAGE-PD Consortium; Glaab, Enrico; Balling, Rudi; Hardy, John A.; Brice, Alexis; Houlden, Henry; Shulman, Joshua M.; Morris, Huw R.; Gasser, Thomas; Heutink, Peter; Krüger, Rejko; Sharma, Manu; Simon-Sanchez, Javier; Nalls, Mike A.; Singleton, Andrew B.; Scholz, Sonja W.

in Neurobiology of Aging (2017)

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See detailRare variant analysis of the PPMI dataset to uncover the complex genetic architecture of Parkinson’s disease
Bobbili, Dheeraj Reddy; May, Patrick; Krüger, Rejko

in Movement Disorders : Official Journal of the Movement Disorder Society (2017, June 02), 322(Supplement S2), 405

See detailData Integration in the Life Sciences
Da Silveira, Marcos; Pruski, Cedric; Schneider, Reinhard

Book published by Springer Verlag (2017)

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See detailConfronting the catalytic dark matter encoded by sequenced genomes
Ellens, Kenneth W.; Christian, Nils; Satagopam, Venkata; May, Patrick; Linster, Carole

in Nucleic Acids Research (2017)

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See detailMetformin reverses TRAP1 mutation-associated alterations in mitochondrial function in Parkinson's disease
Fitzgerald, Julia C.; Zimprich, Alexander; Carvajal-Berrio, Daniel A.; Schindler, Kevin M.; Maurer, Brigitte; Schulte, Claudia; Bus, Christine; Hauser, Anne-Kathrin; Kübler, Manuela; Lewin, Rahel; Bobbili, Dheeraj Reddy; Schwarz, Lisa M.; Vartholomaiou, Evangela; Brockmann, Kathrin; Wüst, Richard; Madlung, Johannes; Nordheim, Alfred; Riess, Olaf; Martins, L. Miguel; Glaab, Enrico; May, Patrick; Schenke-Layland, Katja; Picard, Didier; Sharma, Manu; Gasser, Thomas; Krüger, Rejko

in Brain : A Journal of Neurology (2017), 140(9), 2444-2459

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See detailBiomedical Data Science at LCSB
Glaab, Enrico

Presentation (2017)

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See detailIDENTIFICATION OF A RARE GENE VARIANT THAT IS ASSOCIATED WITH FAMILIAL ALZHEIMER DISEASE AND REGULATES APP EXPRESSION
Hartl, Daniela; May, Patrick; Gu, Wei; Mayhaus, Manuel; Glaab, Enrico; Antony, Paul; Bobbili, Dheeraj Reddy; Köglsberger, Sandra; Pichler, Sabrina; Spaniol, Christian; Kurz, Alexander; Balling, Rudi; Schneider, Jochen; Riemenschneider, Matthias

in Alzheimer's & Dementia : The Journal of the Alzheimer's Association (2017), 13(7, Supplement), 648

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See detailThe Spectrum Of De Novo Variants In Neurodevelopmental Disorders With Epilepsy
Heyne, Henrike O.; EuroEPINOMICS RES Consortium; Abou Jamra, Rami; Caglayan, Hande; Craiu, Dana; De Jonghe, Peter; Guerrini, Renzo; Helbig, Katherine L.; Koeleman, Bobby P. C.; Kosmicki, Jack A.; Linnankivi, Tarja; May, Patrick; Muhle, Hiltrud; Moeller, Rikke S.; Neubauer, Bernd; Palotie, Aarno; Pendziwiat, Manuela; Stamberger, Hannah; Striano, Pasquale; Tang, Sha; Wu, Sitao; Daly, Mark J.; Poduri, Annapurna; Weber, Yvonne; Weckhuysen, Sarah; Sisodiya, Sanjay M.; Helbig, Ingo; Lal, Dennis; Lemke, Johannes R.

E-print/Working paper (2017)

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See detailA systems level analysis of epileptogenesis-associated proteome alterations.
Keck, Michael; Androsova, Ganna; Gualtieri, Fabio; Walker, Andreas; von Ruden, Eva-Lotta; Russmann, Vera; Deeg, Cornelia A.; Hauck, Stefanie M.; Krause, Roland; Potschka, Heidrun

in Neurobiology of disease (2017), 105

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See detailVariant-DB: A Tool for Efficiently Exploring Millions of Human Genetic Variants and Their Annotations
Kutzera, Joachim; May, Patrick

in Da Silveira, Marcos; Pruski, Cédric; Schneider, Reinhard (Eds.) DILS 2017: Data Integration in the Life Sciences (2017, October 24)

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See detailRecessive mutations in SLC35A3 cause early onset epileptic encephalopathy with skeletal defects
Marini, Carla; Hardies, Katia; Pisano, Tiziana; May, Patrick; Weckhuysen, Sarah; Cellini, Elena; Suls, Arvid; Mei, Davide; Balling, Rudi; De Jonghe, Peter; Helbig, Ingo; Garozzo, Domenico; EuroEPINOMICS consortium AR working group; Guerrini, Renzo

in American Journal of Medical Genetics. Part A (2017), 173(4), 1119-1123

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See detailReassessment Of Lesion-Associated Gene And Variant Pathogenicity In Focal Human Epilepsies
Neupert, Lisa Marie; Nothnagel, Michael; May, Patrick; Palotie, Aarno; Daly, Mark; Nürnberg, Peter; Blümcke, Ingmar; Lal, Dennis

E-print/Working paper (2017)

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See detailRare GABRA3 variants are associated with epileptic seizures, encephalopathy and dysmorphic features
Niturad, Elena Christina; Lev, Dorit; Kalscheuer, Vera M; Charzewska, Agnieszka; Schubert, Julian; Lerman-Sagie, Tally; Kroes, Hester Y; Oegema, Renske; Traverso, Monica; Specchio, Nicola; Lassota, Maria; Chelly, Jamel; Bennett-Back, Odeya; Carmi, Nirit; Koffler-Brill, Tal; Iacomino, Michele; Trivisano, Marina; Capovilla, Giuseppe; Striano, Pasquale; Nawara, Magdalena; Rzonca, Sylwia; Fischer, Ute; Bienek, Melanie; Jensen, Corinna; Hu, Hao; Thiele, Holger; Altmüller, Janine; Krause, Roland; May, Patrick; Becker, Felicitas; EuroEPINOMICS Consortium; Balling, Rudi; Biskup, Saskia; Haas, Stefan A; Nürnberg, Peter; van Gassen, Koen L I; Lerche, Holger; Zara, Federico; Maljevic, Snezana; Leshinsky-Silver, Esther

in Brain : A Journal of Neurology (2017)

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See detailBiallelic Variants in OTUD6B Cause an Intellectual Disability Syndrome Associated with Seizures and Dysmorphic Features
Santiago-Sim, Teresa; Burrage, Lindsay C.; Ebstein, Frederic; Tokita, Mary J.; Miller, Marcus; Bi, Weimin; Braxton, Alicia A.; Rosenfeld, Jill A.; Shahrour, Maher; Lehmann, Andrea; Cogne, Benjamin; Küry, Sebastien; Besnard, Thomas; Isidor, Bertrand; Bézieau, Stephane; Hazert, Isabelle; Nagakura, Honey; Immken, LaDonna L.; Littlejohn, Rebecca O.; Roeder, Elizabeth; Euroepinomics Res Consortium ARE working group; Balling, Rudi; Caglayan, Hande; Kara, Bulent; Hardies, Katia; Weckhuysen, Sarah; May, Patrick; Lemke, Johannes R.; Elpeleg, Orly; Abu-Libdeh, Bassam; James, Kiely N.; Slihavy, Jennifer L.; Issa, Mahmoud Y.; Zaki, Maha S.; Gleeson, Joseph G.; Seavitt, John R.; Dickinson, Mary E.; Ljungberg, M. Cecilia; Wells, Sara; Johnson, Sara L.; Teboul, Lydia; Eng, Christine M.; Yang, Yaping; Kloetzel, Peter-Michael; Heaney, Jason D.; Walkiewicz, Magdalena A.

in American Journal of Human Genetics (2017), 100(4), 676-688

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See detailAlterations in the α2δ ligand, thrombospondin-1, in a rat model of spontaneous absence epilepsy and in patients with idiopathic/genetic generalized epilepsies
Santolini, Ines; Celli, Roberta; Cannella, Milena; Imbriglio, Tiziana; Guiducci, Michela; Parisi, Pasquale; Schubert, Julian; Iacomino, Michele; Zara, Federico; Lerche, Holger; EuroEPINOMICS CoGIE Consortium; May, Patrick; Krause, Roland; Balling, Rudi; Genetic Commission of Italian League Against Epilepsy (LICE); Moyanova, Slavianka; Ngomba, Richard Teke; van Luijtellar, Gilles; Battaglia, Giuseppe; Bruno, Valeria; Striano, Pasquale; Nicoletti, Ferdinando

in Epilepsia (2017)

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See detailRare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease
Sims, Rebecca; van der Lee, Sven J.; Naj, Adam C.; Bellenguez, Celine; Badarinarayan, Nandini; Jakobsdottir, Johanna; Kunkle, Brian W.; Boland, Anne; Raybould, Rachel; Bis, Joshua C.; Martin, Eden R.; Grenier-Boley, Benjamin; Heilmann-Heimbach, Stefanie; Chouraki, Vincent; Kuzma, Amanda B.; Sleegers, Kristel; Vronskaya, Maria; Ruiz, Agustin; Graham, Robert R.; Olaso, Robert; Hoffmann, Per; Grove, Megan L.; Vardarajan, Badri N.; Hiltunen, Mikko; Nothen, Markus M.; White, Charles C.; Hamilton-Nelson, Kara L.; Epelbaum, Jacques; Maier, Wolfgang; Choi, Seung-Hoan; Beecham, Gary W.; Dulary, Cecile; Herms, Stefan; Smith, Albert V.; Funk, Cory C.; Derbois, Celine; Forstner, Andreas J.; Ahmad, Shahzad; Li, Hongdong; Bacq, Delphine; Harold, Denise; Satizabal, Claudia L.; Valladares, Otto; Squassina, Alessio; Thomas, Rhodri; Brody, Jennifer A.; Qu, Liming; Sanchez-Juan, Pascual; Morgan, Taniesha; Wolters, Frank J.; Zhao, Yi; Garcia, Florentino Sanchez; Denning, Nicola; Fornage, Myriam; Malamon, John; Naranjo, Maria Candida Deniz; Majounie, Elisa; Mosley, Thomas H.; Dombroski, Beth; Wallon, David; Lupton, Michelle K.; Dupuis, Josee; Whitehead, Patrice; Fratiglioni, Laura; Medway, Christopher; Jian, Xueqiu; Mukherjee, Shubhabrata; Keller, Lina; Brown, Kristelle; Lin, Honghuang; Cantwell, Laura B.; Panza, Francesco; McGuinness, Bernadette; Moreno-Grau, Sonia; Burgess, Jeremy D.; Solfrizzi, Vincenzo; Proitsi, Petra; Adams, Hieab H.; Allen, Mariet; Seripa, Davide; Pastor, Pau; Cupples, L. Adrienne; Price, Nathan D.; Hannequin, Didier; Frank-Garcia, Ana; Levy, Daniel; Chakrabarty, Paramita; Caffarra, Paolo; Giegling, Ina; Beiser, Alexa S.; Giedraitis, Vilmantas; Hampel, Harald; Garcia, Melissa E.; Wang, Xue; Lannfelt, Lars; Mecocci, Patrizia; Eiriksdottir, Gudny; Crane, Paul K.; Pasquier, Florence; Boccardi, Virginia; Henandez, Isabel; Barber, Robert C.; Scherer, Martin; Tarraga, Lluis; Adams, Perrie M.; Leber, Markus; Chen, Yuning; Albert, Marilyn S.; Riedel-Heller, Steffi; Emilsson, Valur; Beekly, Duane; Braae, Anne; Schmidt, Reinhold; Blacker, Deborah; Masullo, Carlo; Schmidt, Helena; Doody, Rachelle S.; Spalletta, Gianfranco; Jr, W. T. Longstreth; Fairchild, Thomas J.; Bossu, Paola; Lopez, Oscar L.; Frosch, Matthew P.; Sacchinelli, Eleonora; Ghetti, Bernardino; Yang, Qiong; Huebinger, Ryan M.; Jessen, Frank; Li, Shuo; Kamboh, M. Ilyas; Morris, John; Sotolongo-Grau, Oscar; Katz, Mindy J.; Corcoran, Chris; Dunstan, Melanie; Braddel, Amy; Thomas, Charlene; Meggy, Alun; Marshall, Rachel; Gerrish, Amy; Chapman, Jade; Aguilar, Miquel; Taylor, Sarah; Hill, Matt; Fairen, Monica Diez; Hodges, Angela; Vellas, Bruno; Soininen, Hilkka; Kloszewska, Iwona; Daniilidou, Makrina; Uphill, James; Patel, Yogen; Hughes, Joseph T.; Lord, Jenny; Turton, James; Hartmann, Annette M.; Cecchetti, Roberta; Fenoglio, Chiara; Serpente, Maria; Arcaro, Marina; Caltagirone, Carlo; Orfei, Maria Donata; Ciaramella, Antonio; Pichler, Sabrina; Mayhaus, Manuel; Gu, Wei; Lleo, Alberto; Fortea, Juan; Blesa, Rafael; Barber, Imelda S.; Brookes, Keeley; Cupidi, Chiara; Maletta, Raffaele Giovanni; Carrell, David; Sorbi, Sandro; Moebus, Susanne; Urbano, Maria; Pilotto, Alberto; Kornhuber, Johannes; Bosco, Paolo; Todd, Stephen; Craig, David; Johnston, Janet; Gill, Michael; Lawlor, Brian; Lynch, Aoibhinn; Fox, Nick C.; Hardy, John; Consortium, A. R. U. K.; Albin, Roger L.; Apostolova, Liana G.; Arnold, Steven E.; Asthana, Sanjay; Atwood, Craig S.; Baldwin, Clinton T.; Barnes, Lisa L.; Barral, Sandra; Beach, Thomas G.; Becker, James T.; Bigio, Eileen H.; Bird, Thomas D.; Boeve, Bradley F.; Bowen, James D.; Boxer, Adam; Burke, James R.; Burns, Jeffrey M.; Buxbaum, Joseph D.; Cairns, Nigel J.; Cao, Chuanhai; Carlson, Chris S.; Carlsson, Cynthia M.; Carney, Regina M.; Carrasquillo, Minerva M.; Carroll, Steven L.; Diaz, Carolina Ceballos; Chui, Helena C.; Clark, David G.; Cribbs, David H.; Crocco, Elizabeth A.; DeCarli, Charles; Dick, Malcolm; Duara, Ranjan; Evans, Denis A.; Faber, Kelley M.; Fallon, Kenneth B.; Fardo, David W.; Farlow, Martin R.; Ferris, Steven; Foroud, Tatiana M.; Galasko, Douglas R.; Gearing, Marla; Geschwind, Daniel H.; Gilbert, John R.; Graff-Radford, Neill R.; Green, Robert C.; Growdon, John H.; Hamilton, Ronald L.; Harrell, Lindy E.; Honig, Lawrence S.; Huentelman, Matthew J.; Hulette, Christine M.; Hyman, Bradley T.; Jarvik, Gail P.; Abner, Erin; Jin, Lee-Way; Jun, Gyungah; Karydas, Anna; Kaye, Jeffrey A.; Kim, Ronald; Kowall, Neil W.; Kramer, Joel H.; LaFerla, Frank M.; Lah, James J.; Leverenz, James B.; Levey, Allan I.; Li, Ge; Lieberman, Andrew P.; Lunetta, Kathryn L.; Lyketsos, Constantine G.; Marson, Daniel C.; Martiniuk, Frank; Mash, Deborah C.; Masliah, Eliezer; McCormick, Wayne C.; McCurry, Susan M.; McDavid, Andrew N.; McKee, Ann C.; Mesulam, Marsel; Miller, Bruce L.; Miller, Carol A.; Miller, Joshua W.; Morris, John C.; Murrell, Jill R.; Myers, Amanda J.; O'Bryant, Sid; Olichney, John M.; Pankratz, Vernon S.; Parisi, Joseph E.; Paulson, Henry L.; Perry, William; Peskind, Elaine; Pierce, Aimee; Poon, Wayne W.; Potter, Huntington; Quinn, Joseph F.; Raj, Ashok; Raskind, Murray; Reisberg, Barry; Reitz, Christiane; Ringman, John M.; Roberson, Erik D.; Rogaeva, Ekaterina; Rosen, Howard J.; Rosenberg, Roger N.; Sager, Mark A.; Saykin, Andrew J.; Schneider, Julie A.; Schneider, Lon S.; Seeley, William W.; Smith, Amanda G.; Sonnen, Joshua A.; Spina, Salvatore; Stern, Robert A.; Swerdlow, Russell H.; Tanzi, Rudolph E.; Thornton-Wells, Tricia A.; Trojanowski, John Q.; Troncoso, Juan C.; Van Deerlin, Vivianna M.; Van Eldik, Linda J.; Vinters, Harry V.; Vonsattel, Jean Paul; Weintraub, Sandra; Welsh-Bohmer, Kathleen A.; Wilhelmsen, Kirk C.; Williamson, Jennifer; Wingo, Thomas S.; Woltjer, Randall L.; Wright, Clinton B.; Yu, Chang-En; Yu, Lei; Garzia, Fabienne; Golamaully, Feroze; Septier, Gislain; Engelborghs, Sebastien; Vandenberghe, Rik; De Deyn, Peter P.; Fernadez, Carmen Munoz; Benito, Yoland Aladro; Thonberg, Hakan; Forsell, Charlotte; Lilius, Lena; Kinhult-Stahlbom, Anne; Kilander, Lena; Brundin, Rosemarie; Concari, Letizia; Helisalmi, Seppo; Koivisto, Anne Maria; Haapasalo, Annakaisa; Dermecourt, Vincent; Fievet, Nathalie; Hanon, Olivier; Dufouil, Carole; Brice, Alexis; Ritchie, Karen; Dubois, Bruno; Himali, Jayanadra J.; Keene, C. Dirk; Tschanz, Joann; Fitzpatrick, Annette L.; Kukull, Walter A.; Norton, Maria; Aspelund, Thor; Larson, Eric B.; Munger, Ron; Rotter, Jerome I.; Lipton, Richard B.; Bullido, Maria J.; Hofman, Albert; Montine, Thomas J.; Coto, Eliecer; Boerwinkle, Eric; Petersen, Ronald C.; Alvarez, Victoria; Rivadeneira, Fernando; Reiman, Eric M.; Gallo, Maura; O'Donnell, Christopher J.; Reisch, Joan S.; Bruni, Amalia Cecilia; Royall, Donald R.; Dichgans, Martin; Sano, Mary; Galimberti, Daniela; St George-Hyslop, Peter; Scarpini, Elio; Tsuang, Debby W.; Mancuso, Michelangelo; Bonuccelli, Ubaldo; Winslow, Ashley R.; Daniele, Antonio; Wu, Chuang-Kuo; GERAD/PERADES, Charge Adgc Eadi; Peters, Oliver; Nacmias, Benedetta; Riemenschneider, Matthias; Heun, Reinhard; Brayne, Carol; Rubinsztein, David C.; Bras, Jose; Guerreiro, Rita; Al-Chalabi, Ammar; Shaw, Christopher E.; Collinge, John; Mann, David; Tsolaki, Magda; Clarimon, Jordi; Sussams, Rebecca; Lovestone, Simon; O'Donovan, Michael C.; Owen, Michael J.; Behrens, Timothy W.; Mead, Simon; Goate, Alison M.; Uitterlinden, Andre G.; Holmes, Clive; Cruchaga, Carlos; Ingelsson, Martin; Bennett, David A.; Powell, John; Golde, Todd E.; Graff, Caroline; De Jager, Philip L.; Morgan, Kevin; Ertekin-Taner, Nilufer; Combarros, Onofre; Psaty, Bruce M.; Passmore, Peter; Younkin, Steven G.; Berr, Claudine; Gudnason, Vilmundur; Rujescu, Dan; Dickson, Dennis W.; Dartigues, Jean-Francois; DeStefano, Anita L.; Ortega-Cubero, Sara; Hakonarson, Hakon; Campion, Dominique; Boada, Merce; Kauwe, John Keoni; Farrer, Lindsay A.; Van Broeckhoven, Christine; Ikram, M. Arfan; Jones, Lesley; Haines, Jonathan L.; Tzourio, Christophe; Launer, Lenore J.; Escott-Price, Valentina; Mayeux, Richard; Deleuze, Jean-Francois; Amin, Najaf; Holmans, Peter A.; Pericak-Vance, Margaret A.; Amouyel, Philippe; van Duijn, Cornelia M.; Ramirez, Alfredo; Wang, Li-San; Lambert, Jean-Charles; Seshadri, Sudha; Williams, Julie; Schellenberg, Gerard D.

in Nature Genetics (2017), 49

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See detailMolecular Identification of D-Ribulokinase in Budding Yeast and Mammals
Singh, Charandeep; Glaab, Enrico; Linster, Carole

in Journal of Biological Chemistry (2017), 292(3), 1005-1028

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See detailPancreatic Fat Is Associated With Metabolic Syndrome and Visceral Fat but Not Beta-Cell Function or Body Mass Index in Pediatric Obesity
Staaf, Johan; Labmayr, Viktor; Paulmichl, Katharina; Manell, Hannes; Schneider, Reinhard; Roomp, Kirsten

in Pancreas (2017)

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2016

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See detailCrowdsourced estimation of cognitive decline and resilience in Alzheimer's disease
Allen, Genevera; Amoroso, Nicola; Anghel, Catalina; Balagurusamy, Venkat; Bare, Christopher; Beaton, Derek; Bellotti, Roberto; Bennett, David; Boehme, Kevin; Caberlotto, Laura; Campbell, Frederick; Chang, Yu-Chuan; Chen, Beibei; Chen, Chien-Yu; Chien, Ting-Ying; Clark, Tim; Das, Sudeshna; Davatzikos, Christos; Deng, Jieyao; Dillenberger, Donna; Dobson, Richard; Dong, Qilin; Doshi, Jimit; Duma, Denise; Errico, Rosangela; Erus, Guray; Everett, Evan; Fardo, David; Friend, Stephen; Fröhlich, Holger; Gan, Jessica; St George-Hyslop, Peter; Ghosh, Satrajit; Glaab, Enrico; Green, Robert; Guan, Yuanfang; Hong, Ming-Yi; Huang, Chao; Hwang, Jinseub; Ibrahim, Joseph; Inglese, Paolo; Jiang, Qijia; Katsumata, Yurik; Kauwe, Jo; Klein, Arno; Kong, Dehan; Krause, Roland; Lalonde, Emilie; Lauria, Mari; Lee, Eunjee; Lin, Xihui; Liu, Zhandong; Livingstone, Julie; Logsdon, Benjami; Lovestone, Simon; Iyappan, Anandhi; Ma, Tsung-wei; Malhotra, Ashutos; Maxwell, Taylor; Merrill, Emily; Nagorski, John; Alex Namasivayam, Aishwarya; Narayan, Manjari; Naz, Mufassra; Neto, Elias Chaibub; Newhouse, Stephen; Norman, Thea; Nurtdinov, Ramil; Oyang, Yen-Jen; Boutros, Paul; Pawitan, Yudi; Peng, Shengwen; Peters, Mette; Piccolo, Stephen; Praveen, Paurush; Priami, Corrado; Sabelnykova, Veronica; Senger, Philipp; Shen, Xia; Simmons, Andrew; Sotiras, Aristeidis; Stolovitzky, Gustavo; Tangaro, Sabina; Tateo, Andrea; Tung, Yi-An; Tustison, Nicholas; Varol, Erdem; Vradenburg, George; Weiner, Michael; Xiao, Guanghua; Xie, Lei; Xie, Yang; Xu, Jia; Yang, Hojin; Zhan, Xiaowei; Zhou, Yunyun; Zhu, Fan; Zhu, Hongtu; Zhu, Shanfeng; Alzheimer's Disease Neuroimaging Initiative

in Alzheimer's & Dementia : The Journal of the Alzheimer's Association (2016), 12(6), 645-653

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in Genome medicine (2016), 8(1), 71

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Birck, Cindy; Koncina, Eric; Heurtaux, Tony; Glaab, Enrico; Michelucci, Alessandro; Heuschling, Paul; Grandbarbe, Luc

in Genomics Data (2016), 7

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in Human Molecular Genetics (2016), 25(3), 459-71

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de Kovel, Carolien G.F.; Brilstra, Eva H.; van Kempen J.A.; van't Slot, Ruben; Nijman, Isaac J.; Afawi, Zaid; De Jonghe, Peter; Djemie, Tania; Guerrini, Renzo; Hardies, Katia; Helbig, Ingo; Hendrickx, Rik; Kanaan, Moine; Kramer, Uri; Lehesjoki, Anna-Elina E.; Lemke, Johannes R.; Marini, Carla; Mei, Davide; Moller, Rikke S.; Pendziwiat, Manuela; Stamberger, Hannah; Suls, Arvid; Weckhuysen, Sarah; EuroEPINOMICS RES Consortium; May, Patrick; Balling, Rudi; Koeleman, Bobby P.C.

in Molecular Genetics & Genomic Medicine (2016), 4(5), 568-80

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Gabel, Sebastien; Koncina, Eric; Dorban, Gauthier; Heurtaux, Tony; Birck, Cindy; Glaab, Enrico; Michelucci, Alessandro; Heuschling, Paul; Grandbarbe, Luc

in Molecular Neurobiology (2016), 53(8), 5041-5055

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in NPJ Systems Biology and Applications (2016)

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in Brain : A Journal of Neurology (2016)

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Heintz-Buschart, Anna; May, Patrick; Laczny, Cedric C.; Lebrun, Laura; Bellora, Camille; Krishna, Abhimanyu; Wampach, Linda; Schneider, Jochen; Hogan, Angela; Beaufort, Carine De; Wilmes, Paul

in Nature microbiology (2016), 2

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See detailIntegrated multi-omics of the human gut microbiome in a case study of familial type 1 diabetes.
Heintz-Buschart, Anna; May, Patrick; Laczny, Cedric C.; Lebrun, Laura; Bellora, Camille; Krishna, Abhimanyu; Wampach, Linda; Schneider, Jochen; Hogan, Angela; de Beaufort, Carine; Wilmes, Paul

in Nature microbiology (2016), 2

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in Stem Cells (2016), 34(12), 28612874

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in Glia (2016), 64(5), 695-715

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in Nucleic Acids Research (2016)

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in Frontiers in Microbiology (2016), 7(884),

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in PLoS ONE (2016)

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in Genome Biology (2016), 17

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in Bioinformatics (2016)

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in Neurobiology of Aging (2016), 50

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in European Journal of Cancer (2016), 61(Suppl.1), 32

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Satagopam, Venkata; Gu, Wei; Eifes, Serge; Gawron, Piotr; Ostaszewski, Marek; Gebel, Stephan; Barbosa-Silva, Adriano; Balling, Rudi; Schneider, Reinhard

in Big data (2016), 4(2), 97-108

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in Bioinformatics (2016), 32(3), 474-6

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Shah, Pranjul; Fritz, Joëlle; Glaab, Enrico; Desai, Mahesh S.; Greenhalgh, Kacy; Frachet Bour, Audrey; Niegowska, Magdalena; Estes, Matthew; Jäger, Christian; Seguin-Devaux, Carole; Zenhausern, Frederic; Wilmes, Paul

in Nature communications (2016), 7

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in Proceedings of the National Academy of Sciences of the United States of America (2016), 113(9), 1180-9

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2015

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Ameziane, Najim; May, Patrick; Van de Vrugt, Henri J.; Van Rossum-Fikkert, Sari E.; Ristic, Dejan; Williams, Gareth J.; Balk, Jesper; Rockx, Davy; Li, Hong; Rooimans, Martin A.; Oostra, Anneke B.; Velleuer, Eunike; Dietrich, Ralf; Bleijerveld, Onno B.; Altelaar, A.F. Maarten; Meijers-Heijboer, Hanne; Joenje, Hans; Glusman, Gustavo; Roach, Jared C.; Hood, Leroy; Galas, David J.; Balling, Rudi; den Dunnen, Johan; De Winter, Johan P.; Kanaar, Roland; Gelinas, Richard; Dorsman, Josephine C.

in Nature Communications (2015), 6(8829),

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in G3 (2015)

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in JAK-STAT (2015), 4(1), 1062596

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in Brain : A Journal of Neurology (2015)

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in Human Molecular Genetics (2015), 24(8), 2218-2227

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Hofmann-Apitius, Matin; Ball, Gordon; Gebel, Stephan; de Bono, ; Schneider, Reinhard; Page, M.; Kodamulli, AT.; Younesi, E.; Ebeling, C.; Tegner, J.; Canard, L.

in International Journal of Molecular Sciences (2015), 16(12), 29179-29206

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in Nature chemical biology (2015), 11(5), 347354

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in PloS one (2015), 10(3), 0119807

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in Epilepsy research (2015), 115

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in Oncotarget (2015), 6(14), 12110-27

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in Applications of Evolutionary Computation: 18th European Conference, EvoApplications 2015, Copenhagen, Denmark, April 8-10, 2015, Proceedings (2015)

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in Nature Communications (2015), 6

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in Plant Cell (2015), 27(10), 2692-2708

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in Journal of Feline Medicine and Surgery (2015)

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in Nature Genetics (2015), 47(4), 393-9

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See detailCHD2 myoclonic encephalopathy is frequently associated with self-induced seizures
Thomas, Rhys H.; Zhang, Lin Mei; Carvill, Gemma L.; Archer, John S.; Heavin, Sinéad B.; Mandelstam, Simone A.; Craiu, Dana; Berkovic, Samuel F.; Gill, Deepak S.; Mefford, Heather C.; Scheffer, Ingrid E.; Paalotie, Aarno; Lehesjoki, Anna-Elina; Koeleman, Bobby; Marini, Carla; Depienne, Christel; Pal, Deb; Hoffman-Zacharska, Dorota; Leguern, Eric; Zara, Federico; Rosenow, Felix; Caglayan, Hande; Hjalgrim, Helle; Muhle, Hiltrud; Lerche, Holger; Helbig, Ingo; Jähn, Johanna; Lemke, Johannes; Serratosa, Jose M.; Selmer, Katja; Klein, Karl Martin; Sterbova, Katalin; Pendziwiat, Manuela; Barisic, Nina; Gormley, Padhraig; Striano, Pasquale; May, Patrick; De Jonghe, Peter; Guerrini, Renzo; Møller, Rikke S.; Krause, Roland; Balling, Rudi; Sisodiya, Sanjay; von Spiczak, Sarah; Weckhuysen, Sarah; Baulac, Stéphanie; Suls, Arvid; Djemie, Tania; Stephani, Ulrich; Komarek, Vladimir; Weber, Yvonne

in Neurology (2015), 84(9), 951-958

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See detailA guide for building biological pathways along with two case studies: hair and breast development.
Trindade, Daniel; Orsine, Lissur A.; Barbosa Da Silva, Adriano; Donnard, Elisa R.; Ortega, J. Miguel

in Methods (San Diego, Calif.) (2015), 74

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See detailGenePEN: analysis of network activity alterations in complex diseases via the pairwise elastic net
Vlassis, Nikos; Glaab, Enrico

in Statistical Applications in Genetics and Molecular Biology (2015), 14(2), 221-224

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2014

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See detailDe Novo Mutations in Synaptic Transmission Genes Including DNM1 Cause Epileptic Encephalopathies
Appenzeller, Silke; Balling, Rudi; Barisic, Nina; Baulac, Stephanie; Caglayan, Hande; Craiu, Dana; De Jonghe, Peter; Depienne, Christel; Dimova, Petia; Djemie, Tania; Gormly, Padhraig; Guerrini, Renzo; Helbig, Ingo; Hjalgrim, Helle; Hoffman-Zacharska, Dorota; Jähn; Klein, Karl Martin; Koeleman, Bobby; Komarek, Vladimir; Krause, Roland; Kuhlenbäumer, Gregor; Leguern, Eric; Lehesjoki, Anna-Elina; Lemke, Johannes R.; Lerche, Holger; Linnankivi, Tarja; Marini, Carla; May, Patrick; Møller, Rikke S.; Muhle, Hiltrud; Pal, Deb; Palotie, Aarno; Pendziwitat, Manuela; Robbiano, Angela; Roelens, Filip; Rosenow, Felix; Selmer, Kaja; Serratosa, Jose M.; Sisodiya, Sanjay; Stephani, Ulrich; Sterbova, Katalin; Striano, Pasquale; Suls, Arvid; Talvik, Tiina; von Spizak, Sarah; Weber, Yvonne; Weckhuysen, Sarah; Zara, Frederico; Epilepsy Phenome/Genome Project; Epi4K Consortium

in American Journal of Human Genetics (2014), 4

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See detailCOMPARTMENTS: unification and visualization of protein subcellular localization evidence.
Binder, Janos X.; Pletscher-Frankild, Sune; Tsafou, Kalliopi; Stolte, Christian; O'Donoghue, Sean I.; Schneider, Reinhard; Jensen, Lars Juhl

in Database : the journal of biological databases and curation (2014), 2014

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See detailMesoscopic behavior from microscopic Markov dynamics and its application to calcium release channels.
Christian, Nils; Skupin, Alexander; Morante, Silvia; Karl, Jansen; Rossi, Giancarlo; Ebenhöh, Oliver

in Journal of Theoretical Biology (2014), 343

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See detailThe HIV Mutation Browser: A Resource for Human Immunodeficiency Virus Mutagenesis and Polymorphism Data
Davey, Norman E.; Satagopam, Venkata; Santiago-Mozos, Salvador; Villacorta-Martin, Carlos; Bharat, Tanya A.M.; Schneider, Reinhard; Briggs, John A.G.

in PLoS Computational Biology (2014)

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See detailMolecular and Clinical Evidence for an ARMC5 Tumor Syndrome: Concurrent Inactivating Germline and Somatic Mutations are Associated with both Primary Macronodular Adrenal Hyperplasia and Meningioma
Eibelt, Ulf; Trovato, Alissa; Kloth, Michael; Gentz, Enno; Finke, Reinhard; Spranger, Joachim; Galas, David J.; Weber, Susanne; Wolf, Cristina-Alexandra; König, Katharina; Arlt, Wiebke; Büttner, Reinhard; May, Patrick; Allolio, Bruno; Schneider, Jochen

in Journal of Clinical Endocrinology and Metabolism (2014)

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See detailFrontotemporal dementia and its subtypes: a genome-wide association study.
Ferrari, Raffaele; Hernandez, Dena G.; Nalls, Michael A.; Rohrer, Jonathan D.; Ramasamy, Adaikalavan; Kwok, John B. J.; Dobson-Stone, Carol; Brooks, William S.; Schofield, Peter R.; Halliday, Glenda M.; Hodges, John R.; Piguet, Olivier; Bartley, Lauren; Thompson, Elizabeth; Haan, Eric; Hernandez, Isabel; Ruiz, Agustin; Boada, Merce; Borroni, Barbara; Padovani, Alessandro; Cruchaga, Carlos; Cairns, Nigel J.; Benussi, Luisa; Binetti, Giuliano; Ghidoni, Roberta; Forloni, Gianluigi; Galimberti, Daniela; Fenoglio, Chiara; Serpente, Maria; Scarpini, Elio; Clarimon, Jordi; Lleo, Alberto; Blesa, Rafael; Waldo, Maria Landqvist; Nilsson, Karin; Nilsson, Christer; Mackenzie, Ian R. A.; Hsiung, Ging-Yuek R.; Mann, David M. A.; Grafman, Jordan; Morris, Christopher M.; Attems, Johannes; Griffiths, Timothy D.; McKeith, Ian G.; Thomas, Alan J.; Pietrini, P.; Huey, Edward D.; Wassermann, Eric M.; Baborie, Atik; Jaros, Evelyn; Tierney, Michael C.; Pastor, Pau; Razquin, Cristina; Ortega-Cubero, Sara; Alonso, Elena; Perneczky, Robert; Diehl-Schmid, Janine; Alexopoulos, Panagiotis; Kurz, Alexander; Rainero, Innocenzo; Rubino, Elisa; Pinessi, Lorenzo; Rogaeva, Ekaterina; St George-Hyslop, Peter; Rossi, Giacomina; Tagliavini, Fabrizio; Giaccone, Giorgio; Rowe, James B.; Schlachetzki, Johannes C. M.; Uphill, James; Collinge, John; Mead, Simon; Danek, Adrian; Van Deerlin, Vivianna M.; Grossman, Murray; Trojanowski, John Q.; van der Zee, Julie; Deschamps, William; Van Langenhove, Tim; Cruts, Marc; Van Broeckhoven, Christine; Cappa, Stefano F.; Le Ber, Isabelle; Hannequin, Didier; Golfier, Veronique; Vercelletto, Martine; Brice, Alexis; Nacmias, Benedetta; Sorbi, Sandro; Bagnoli, Silvia; Piaceri, Irene; Nielsen, Jorgen E.; Hjermind, Lena E.; Riemenschneider, Matthias; Mayhaus, Manuel; Ibach, Bernd; Gasparoni, Gilles; Pichler, Sabrina; Gu, Wei; Rossor, Martin N.; Fox, Nick C.; Warren, Jason D.; Spillantini, Maria Grazia; Morris, Huw R.; Rizzu, Patrizia; Heutink, Peter; Snowden, Julie S.; Rollinson, Sara; Richardson, Anna; Gerhard, Alexander; Bruni, Amalia C.; Maletta, Raffaele; Frangipane, Francesca; Cupidi, Chiara; Bernardi, Livia; Anfossi, Maria; Gallo, Maura; Conidi, Maria Elena; Smirne, Nicoletta; Rademakers, Rosa; Baker, Matt; Dickson, Dennis W.; Graff-Radford, Neill R.; Petersen, Ronald C.; Knopman, David; Josephs, Keith A.; Boeve, Bradley F.; Parisi, Joseph E.; Seeley, William W.; Miller, Bruce L.; Karydas, Anna M.; Rosen, Howard; van Swieten, John C.; Dopper, Elise G. P.; Seelaar, Harro; Pijnenburg, Yolande A. L.; Scheltens, Philip; Logroscino, Giancarlo; Capozzo, Rosa; Novelli, Valeria; Puca, Annibale A.; Franceschi, Massimo; Postiglione, Alfredo; Milan, Graziella; Sorrentino, Paolo; Kristiansen, Mark; Chiang, Huei-Hsin; Graff, Caroline; Pasquier, Florence; Rollin, Adeline; Deramecourt, Vincent; Lebert, Florence; Kapogiannis, Dimitrios; Ferrucci, Luigi; Pickering-Brown, Stuart; Singleton, Andrew B.; Hardy, John; Momeni, Parastoo

in Lancet neurology (2014), 13(7), 686-99

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See detailIntegrating Pathways of Parkinson's Disease in a Molecular Interaction Map
Fujita, Kazuhiro A.; Ostaszewski, Marek; Matsuoka, Yukiko; Ghosh, Samik; Glaab, Enrico; Trefois, Christophe; Crespo, Isaac; Perumal, Thanneer Malai; Jurkowski, Wiktor; Antony, Paul; Diederich, Nico; Buttini, Manuel; Kodama, Akihiko; Satagopam, Venkata; Eifes, Serge; del Sol Mesa, Antonio; Schneider, Reinhard; Kitano, Hiroaki; Balling, Rudi

in Molecular Neurobiology (2014)

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See detailChIP-seq profiling of the active chromatin marker H3K4me3 and PPARγ, CEBPα and LXR target genes in human SGBS adipocytes
Galhardo, Mafalda Sofia; Sinkkonen, Lasse; Berninger, Philipp; Lin, Jake; Sauter, Thomas; Heinäniemi, Merja

in Genomics Data (2014), 2

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See detailTranscriptomics profiling of human SGBS adipogenesis
Galhardo, Mafalda Sofia; Sinkkonen, Lasse; Berninger, Philipp; Lin, Jake; Sauter, Thomas; Heinäniemi, Merja

in Genomics Data (2014), 2

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See detailG-DNA – a highly efficient multi-GPU/MPI tool for aligning nucleotide reads
Gawron, Piotr; Frohmberg, W; Kierzynka, M; Blazewicz, J; Wojciechowski, P

in Bulletin of the Polish Academy of Sciences. Technical Sciences (2014)

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See detailAddressing Technical Replicate Variance in Omics Data Analysis
Glaab, Enrico; Schneider, Reinhard

Poster (2014)

See detailIntegrated Omic Analyses of the Human Gut Microbiome in a Multiplex Family Study of Type 1 Diabetes Mellitus
Heintz, Anna; May, Patrick; Laczny, Cédric; Lebrun, Laura; Wampach, Linda; Hogan, Angela; Schneider, Jochen; Wilmes, Paul; De Beaufort, Carine

Poster (2014, April 30)

See detailDynamic modelling of ROS management and ROS-induced mitophagy
Kolodkin, Alexey; Ignatenko, Andrew; Sangar, Vineet; Glaab, Enrico; Peters, Bernhard; Price, Nathan; Brady, Nathan; Balling, Rudi

Poster (2014, June)

See detailROS-management in Parkinson’s disease: Dynamic blue-print domino-based model and design principles study. Dynamic modelling of ROS management and ROS-induced mitophagy
Kolodkin, Alexey; Ignatenko, Andrew; Sangar, Vineet; Simeonidis, Vangelis; Glaab, Enrico; Peters, Bernhard; Brady, Nathan; Price, Nathan; Balling, Rudi

Poster (2014, October)

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See detailSystems genomics evaluation of the SH-SY5Y neuroblastoma cell line as a model for Parkinson’s disease
Krishna, Abhimanyu; Biryukov, Maria; Trefois, Christophe; Antony, Paul; Hussong, Rene; Lin, Jake; Heinäniemi, Merja; Glusman, Gustavo; Köglsberger, Sandra; Boyd, Olga; van den Berg, Bart H.J.; Linke, Dennis; Huang, David; Wang, Kai; Hood, Leroy; Tholey, Andreas; Schneider, Reinhard; Galas, David J.; Balling, Rudi; May, Patrick

in BMC Genomics (2014), 15(1154),

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See detailMercator: A fast and simple web server for genome scale functional annotation of plant sequence data
Lohse, Marc; Nagel, Axel; Herter, Thomas; May, Patrick; Schroda, Michael; Zrenner, Rita; Tohge, Takayuki; Fernie, Alisdair R.; Stitt, Mark; Usadel, Bjorn

in Plant, Cell & Environment (2014), 37(5), 1250-8

See detailCommunity integrated omics links the dominance of a microbial generalist to fine-tuned resource usage
Muller, Emilie; Pinel, Nicolás; Laczny, Cédric; Hoopmann, Michael; Lebrun, Laura; Roume, Hugo; May, Patrick; Hicks, Nathan; Liu, Cindy; Price, Lance; Gillece, John; Guignard, Cédric; Schupp, James; Vlassis, Nikos; Moritz, Robert; Baliga, Nitin; Keim, Paul; Wilmes, Paul

Scientific Conference (2014)

See detailCommunity integrated omics links the dominance of a microbial generalist to fine-tuned resource usage
Muller, Emilie; Pinel, Nicolás; Laczny, Cédric; Hoopmann, Michael; Lebrun, Laura; Roume, Hugo; May, Patrick; Hicks, Nathan; Liu, Cindy; Price, Lance; Gillece, John; Guignard, Cédric; Schupp, James; Vlassis, Nikos; Moritz, Robert; Baliga, Nitin; Keim, Paul; Wilmes, Paul

Poster (2014)

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See detailCommunity-integrated omics links dominance of a microbial generalist to fine-tuned resource usage
Muller, Emilie; Pinel, Nicolas; Laczny, Cédric; Hoopmann, Michael; Narayanasamy, Shaman; Lebrun, Laura; Roume, Hugo; Lin, Jake; May, Patrick; Hicks, Nathan; Buschart, Anna; Wampach, Linda; Liu, Cindy; Price, Lance; Gillece, John; Guignard, Cédric; Schupp, James; Vlassis, Nikos; Baliga; Moritz, Robert; Keim, Paul; Wilmes, Paul

in Nature Communications (2014)

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See detailDe novo mutations in HCN1 cause early infantile epileptic encephalopathy
Nava, Caroline; Dalle, Carine; Rastetter, Agnès; Striano, Pasquale; de Kovel, Carolien G. F.; Nabbout, Rima; Cancès, Claude; Ville, Dorothée; Brilstra, Eva H.; Gobbi, Giuseppe; Raffo, Emmanuel; Bouteiller, Delphine; Marie, Yannick; Trouillard, Oriane; Robbiano, Angela; Keren, Boris; Agher, Dahbia; Roze, Emmanuel; Lesage, Suzanne; Nicolas, Aude; Brice, Alexis; Baulac, Michel; Vogt, Cornelia; El Hajj, Nady; Schneider, Eberhard; Suls, Arvid; Weckhuysen, Sarah; Gormley, Padhraig; Lehesjoki, Anna-Elina; De Jonghe, Peter; Helbig, Ingo; Baulac, Stephanie; Zara, Federico; Koeleman, Bobby P. C.; Consortium, Euroepinomics R. E. S.; Haaf, Thomas; LeGuern, Eric; Depienne, Christel; May, Patrick; Balling, Rudi; Barisic, Nina; Baulac, Stéphanie; Caglayan, Hande S.; Craiu, Dana C.; De Jonghe, Peter; Depienne, Christel; Gormley, Padhraig; Guerrini, Renzo; Helbig, Ingo; Hjalgrim, Helle; Hoffman-Zacharska, Dorota; Jähn, Johanna; Klein, Karl Martin; Koeleman, Bobby P. C.; Komarek, Vladimir; Krause, Roland; LeGuern, Eric; Lehesjoki, Anna-Elina; Lemke, Johannes R.; Lerche, Holger; Marini, Carla; Møller, Rikke S.; Muhle, Hiltrud; Palotie, Aarno; Pal, Deb; Rosenow, Felix; Selmer, Kaja; Serratosa, José M.; Sisodiya, Sanjay; Stephani, Ulrich; Sterbova, Katalin; Striano, Pasquale; Suls, Arvid; Talvik, Tiina; von Spiczak, Sarah; Weber, Yvonne; Weckhuysen, Sarah; Zara, Federico

in Nature Genetics (2014)

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See detailEvolutionary multi objective optimisation with diversity as objective for the protein structure similarity problem
Nielsen, Sune Steinbjorn; Jurkowski, Wiktor; Danoy, Grégoire; Jimenez Laredo, Juan Luis; Schneider, Reinhard; Talbi, El-Ghazali; Bouvry, Pascal

Scientific Conference (2014)

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See detailEvolutionary Multi-Objective Optimisation with Quantile Constraint for the Protein Structure Similarity Problem
Nielsen, Sune Steinbjorn; Jurkowski, Wiktor; Danoy, Grégoire; Jimenez Laredo, Juan Luis; Schneider, Reinhard; Talbi, El-Ghazali; Bouvry, Pascal

Scientific Conference (2014)

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See detailBioTextQuest+: a knowledge integration platform for literature mining and concept discovery
Papanikolaou, Nikolas; Pavlopoulos, Georgios A.; Pafilis, Evangelos; Theodosiou, Theodosios; Schneider, Reinhard; Satagopam, Venkata P.; Ouzounis, Christos; Eliopoulos, Arisitdes; Promponas, Vasilis; Iliopoulos, Ioannis

in Bioinformatics (2014)

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See detailAnalysis of ELP4, SRPX2, and interacting genes in typical and atypical rolandic epilepsy
Reinthaler, E.; Lal, D.; Jurkowski, Wiktor; Feucht, M.; Steinböck, H.; Gruber-Sedlmayr, U.; Ronen, G.; Geldner, J.; Haberlandt, E.; Neophytou, B.; Hahn, A.; Altmüller, J.; Thiel, H.; Toliat, M.; Lerche, H.; Nürnberg, Peter; Sander, T.; Neubauer, B.; Zimprich, F.

in Epilepsia (2014), 55(8), 8993

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See detailMutations in STX1B, encoding a presynaptic protein, cause fever-associated epilepsy syndromes
Schubert, Julian; Siekierska, Aleksandra; Langlois, Melanie; May, Patrick; Huneau, Clement; Becker, Felicitas; Muhle, Hiltrud; Suls, Arvid; Lemke, Johannes R.; de Kovel, Carolien G. F.; Thiele, Holger; Konrad, Kathryn; Kawalia, Amit; Toliat, Mohammad R.; Sander, Thomas; Ruschendorf, Franz; Caliebe, Almuth; Nagel, Inga; Kohl, Bernard; Kecskes, Angela; Jacmin, Maxime; Hardies, Katia; Weckhuysen, Sarah; Riesch, Erik; Dorn, Thomas; Brilstra, Eva H.; Baulac, Stephanie; Moller, Rikke S.; Hjalgrim, Helle; Koeleman, Bobby P. C.; EuroEPINOMICS RES Consortium; Krause, Roland; Jurkat-Rott, Karin; Lehman-Horn, Frank; Roach, Jared C.; Glusman, Gustavo; Hood, Leroy; Galas, David J.; Martin, Benoit; de Witte, Peter A. M.; Biskup, Saskia; De Jonghe, Peter; Helbig, Ingo; Balling, Rudi; Nurnberg, Peter; Crawford, Alexander Dettmar; Esguerra, Camila V.; Weber, Yvonne G.; Lerche, Holger

in Nature Genetics (2014), 46(12), 1327-32

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See detailReproducible Research Results R3
Trefois, Christophe; Jarosz, Yohan; Gu, Wei; Satagopam, Venkata; Coronado, Sergio; Schneider, Reinhard

Poster (2014, December)

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See detailManagement of an Academic HPC Cluster: The UL Experience
Varrette, Sébastien; Bouvry, Pascal; Cartiaux, Hyacinthe; Georgatos, Fotis

in Proc. of the 2014 Intl. Conf. on High Performance Computing Simulation (HPCS 2014) (2014, July)

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See detailHippocampal extracellular matrix levels and stochasticity in synaptic protein expression increase with age and are associated with age-dependent cognitive decline.
Vegh, Marlene J.; Rausell, Antonio; Loos, Maarten; Heldring, Celine M.; Jurkowski, Wiktor; van Nierop, Pim; Paliukovich, Iryna; Li, Ka Wan; del Sol Mesa, Antonio; Smit, August B.; Spijker, Sabine; van Kesteren, Ronald E.

in Molecular & cellular proteomics : MCP (2014)

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See detailuORFdb--a comprehensive literature database on eukaryotic uORF biology.
Wethmar, Klaus; Barbosa Da Silva, Adriano; Andrade-Navarro, Miguel A.; Leutz, Achim

in Nucleic acids research (2014), 42(1), 60-7

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See detailPredictProtein--an open resource for online prediction of protein structural and functional features
Yachdav, Guy; Kloppman; Kajan; Hecht; Goldberg; Hamp; Honigschmid; Schafferhans; Roos, Manfred; Bernhofer; Richter; Ashkenazy; Punta; Schlessinger; Bromberg; Schneider, Reinhard; Vriend; Sander; Ben-Tal; Rost

in Nucleic Acid Research (2014), 42(8),

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2013

See detailDifferentiated SH-SY5Y Cells as PD Model for Mitochondrial Dysfunction: From Whole Genome Sequencing to an Educated Design of High-Throughput Experiments
Antony, Paul; Krishna, Abhimanyu; May, Patrick; Trefois, Christophe; Boyd, Olga; Köglsberger, Sandra; Baumuratov, Aidos; Galas, David J.; Balling, Rudi

Poster (2013)

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See detailGenome-wide identification and functional analyses of microRNA signatures associated with cancer pain.
Bali, Kiran Kumar; Selvaraj, Deepitha; Satagopam, Venkata; Lu, Jianning; Schneider, Reinhard; Kuner, Rohini

in EMBO Molecular Medicine (2013), 5(11), 1740-58

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See detailTranscriptional mechanisms underlying sensitization of peripheral sensory neurons by Granulocyte-/Granulocyte-macrophage colony stimulating factors.
Bali, Kiran Kumar; Venkataramani, Varun; Satagopam, Venkata; Gupta, Pooja; Schneider, Reinhard; Kuner, Rohini

in Molecular pain (2013), 9(1), 48

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See detailFunctional Genomics, Proteomics, Metabolomics and Bioinformatics for Systems Biology
Ballereau, S.; Glaab, Enrico; Kolodkin, Alexey; Chaiboonchoe, A.; Biryukov, Maria; Vlassis, Nikos; Ahmed, H.; Pellet, J.; Baliga, N.; Hood, Leroy; Schneider, Reinhard; Balling, Rudi; Auffray, C.

in Prokop, Ales; Csukás, Bela (Eds.) Systems Biology: Integrative Biology and Simulation Tools (2013)

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See detailNetwork analysis for systems biology
Chaiboonchoe, A.; Jurkowski, Wiktor; Pellet, J.; Glaab, Enrico; Kolodkin, Alexey; Raussel, Antonio; Le Béchec, Antony; Meyniel, L.; Ballereau, S.; Crespo, Isaac; Ahmed, H.; Volpert, V.; Lotteau, V.; Baliga, N.; Hood, Leroy; del Sol, A.; Balling, Rudi; Auffray, C.

in Prokop, Aleš; Csukás (Eds.) Springer book in Systems Biology, Vol.1: Systems Biology:, Integrative Biology and Simulation Tools (2013)

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See detailOn different aspects of network analysis in systems biology
Chaiboonchoe, Amphun; Jurkowski, Wiktor; Pellet, Johann; Glaab, Enrico; Kolodkin, Alexey; Raussel, Antonio; Le Béchec, Antony; Ballereau, Stéphane; Meyniel, Laurene; Crespo, Isaac; Ahmed, Hassan; Volpert, Vitaly; Lotteau, Vincent; Baliga, Nitin; Hood, Leroy; Sol, Antonio del; Balling, Rudi; Auffray, Charles

in Systems Biology (2013), 1

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See detailSignaling in Insulin-Secreting MIN6 Pseudoislets and Monolayer Cells.
Chowdhury, Azazul; Satagopam, Venkata; Manukyan, Levon; Artemenko, Konstantin A.; Fung, Yi Man Eva; Schneider, Reinhard; Bergquist, Jonas; Bergsten, Peter

in Journal of proteome research (2013)

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See detailPredicting missing expression values in gene regulatory networks using a discrete logic modeling optimization guided by network stable states
Crespo, Isaac; Krishna, Abhimanyu; Le Béchec, Antony; del Sol Mesa, Antonio; *Co-first-authors

in Nucleic Acids Research (2013), 41(1), 8

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See detailGenomic Sequence Diversity and Population Structure of Saccharomyces cerevisiae Assessed by RAD-seq
Cromie, Gareth A.; Hyma, Katie E.; Ludlow, Catherine L.; Garmendia-Torres, Cecilia; Gilbert, Teresa L.; May, Patrick; Huang, Angela A.; Dudley, Aimée M.; Fay, Justin C.

in Genes, Genomes and Genomics (2013), 3(12), 2163-2171

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See detailThe Young PI Buzz: Learning from the Organizers of the Junior Principal Investigator Meeting at ISMB-ECCB 2013.
de Ridder, Jeroen; Bromberg, Yana; Michaut, Magali; Satagopam, Venkata; Corpas, Manuel; Macintyre, Geoff; Alexandrov, Theodore

in PLoS computational biology (2013), 9(11), 1003350

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See detailA novel GATA6 mutation in a child with congenital heart malformation and neonatal diabetes.
Eifes, Serge; Chudasama, Kishan K.; Molnes, Janne; Wagner, Kerstin; Hoang, Tuyen; Schierloh, Ulrike; Rocour-Brumioul, Danielle; Johansson, Stefan; Njolstad, Pal R.; De Beaufort, Carine

in Clinical Case Reports (2013), 1(2), 86-90

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See detailIntegrated analysis of transcript-level regulation of metabolism reveals disease-relevant nodes of the human metabolic network
Galhardo, Mafalda Sofia; Sinkkonen, Lasse; Berninger, Philippe; Lin, Jake; Sauter, Thomas; Heinäniemi, Merja

in Nucleic Acids Research (2013)

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See detailComputational infrastructures for data and knowledge management in systems biology
Georgatos, Fotis; Ballereau, S.; Pellet, J.; Ghanem, M.; Price, N.; Hood, Leroy; Guo, Y. K.; Boutigny, D.; Auffray, C.; Balling, Rudi; Schneider, Reinhard

in Prokop, Ales; Csukás, Bela (Eds.) Systems Biology: Integrative Biology and Simulation Tools (2013)

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See detailA Protein Prioritization Approach Tailored for the FA/BRCA Pathway
Haitjema, Anneke; Brandt, Bernd W.; Ameziane, Najim; May, Patrick; Heringa, Jaap; de Winter, Johan P. Joenje; Dorsman, Josephine C.

in PLoS ONE (2013), 8(4), 62017

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See detailIAnn: An event sharing platform for the life sciences
Jimenez, Rafael; Albar, Juan; Bhak, Jong; Blatter, Marie-Claude; Blicher, Thomas; Brazas, Michelle; Brooksbank, Cath; Budd, Aidan; Rivas, Javier De Las; Dreyer, Jacqueline; van Driel, Marc A.; Dunn, Michael J.; Fernandes, Pedro L.; van Gelder, Celia W. G.; Hermjakob, Henning; Ioannidis, Vassilios; Judge, David P.; Kahlem, Pascal; Korpelainen, Eija; Kraus, Hans-Joachim; Loveland, Jane; Mayer, Christine; McDowall, Jennifer; Moran, Federico; Mulder, Nicola; Nyronen, Tommi; Rother, Kristian; Salazar, Gustavo; Schneider, Reinhard; Via, Allegra; Villaveces, Jose M.; Yu, Ping; Schneider, Maria V.; Attwood, Teresa; Corpas, Manuel

in Bioinformatics (2013)

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See detailLigand binding properties of human galanin receptors
Jurkowski, Wiktor; Yarzdi, Samira; Elofsson, Arne

in Molecular Mebrance Biology (2013), 30(2), 206-216

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See detailHierarchical representation of supersecondary structures using a graph-theoretical approach.
Koch, Ina; Kreuchwig, Annika; May, Patrick

in Methods in Molecular Biology (Clifton, N.J.) (2013), 932

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See detailPOMO - Plotting Omics analysis results for Multiple Organisms
Lin, Jake; Kreisberg, Richard; Kallio, Aleksi; Dudley, Aimee M.; Nykter, Matti; Shmulevich, Ilya; May, Patrick; Autio, Reija

in BMC Genomics (2013), 14(918),

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See detailHigh-throughput tetrad analysis
Ludlow, Catherine L.; Scott, Adrian C.; Cromie, Gareth A.; Jeffery, Eric W.; Sirr, Amy; May, Patrick; Lin, Jake; Gilbert, Teresa L.; Hays, Michelle; Dudley, Aimée M.

in Nature Methods (2013), 10

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See detailNew Target Genes of MITF-Induced microRNA-211 Contribute to Melanoma Cell Invasion
Margue, Christiane; Philippidou, Demetra; Reinsbach, Susanne; Schmitt, Martina; Behrmann, Iris; Kreis, Stephanie

in PLoS ONE (2013)

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See detailThe Effects of Carbon Dioxide and Temperature on microRNA Expression in Arabidopsis Development
May, Patrick; Liao, Will; Wu, Yijin; Shuai, Bin; McCombie, W. Richard; Zhang, Michael; Liu, Qiong

in Nature Communications (2013), 4(2145),

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See detailCondensing the omics fog of microbial communities
Muller, Emilie; Glaab, Enrico; May, Patrick; Vlassis, Nikos; Wilmes, Paul

in Trends in Microbiology (2013), 21(7), 325333

See detailSystematic molecular measurements reveal key microbial populations driving community-wide phenotype
Muller, Emilie; Pinel, Nicolás; May, Patrick; Hussong, René; Roume, Hugo; Lebrun, Laura; liu, Cindy; Aziz, Maliha; Price, Lance; Moritz, Robert; Schupp, James; Keim, Paul; Wilmes, Paul

Poster (2013)

See detailLinking mixed microbial community phenotype to individual genotypes
Muller, Emilie; Pinel, Nicolás; May, Patrick; Roume, Hugo; Wilmes, Paul

Poster (2013)

See detailA model microbial community for Eco-Systems Biology
Muller, Emilie; Roume, Hugo; Buschart, Anna; Pinel, Nicolas; Laczny, Cédric; Satagopam, Venkata; May, Patrick; Lebrun, Laura; Wilmes, Paul

Poster (2013)

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See detailInterplay of microRNAs, transcription factors and target genes: Linking dynamic expression changes to function
Nazarov, P. V. A; Reinsbach, Susanne; Muller, A. A; Nicot, N. A; Philippidou, Demetra; Vallar, L. A; Kreis, Stephanie

in Nucleic Acids Research (2013), 41(5), 2817-2831

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See detailThe Parkinson's Disease Map: A Framework for Integration, Curation and Exploration of Disease-related Pathways
Ostaszewski, Marek; Fujita, Kazuhiro; Matsuoka, Yukiko; Ghosh, Samik; Glaab, Enrico; Trefois, Christophe; Crespo, Isaac; Perumal, Thanneer Malai; Jurkowski, Wiktor; Antony, Paul; Diederich, Nico; Buttini, Manuel; Kolodkin, Alexey; Kodama, Akihiko; Satagopam, Venkata; Biryukov, Maria; Eifes, Serge; del Sol Mesa, Antonio; Schneider, Reinhard; Kitano, Hiroaki; Balling, Rudi

Poster (2013, March 09)

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See detailOnTheFly 2.0: a tool for automatic annotation of files and biological information extraction.
Pafilis, Evangelos; Pavlopoulos, Georgios; Satagopam, Venkata; Papanikolaou, Nikolas; Horn, Heiko; Arvanitidis, Christos; Jensen, Lars Juhl; Schneider, Reinhard; Iliopoulos, Ioannis

Poster (2013)

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See detailThe C-terminal cavity of the Na,K-ATPase analyzed by docking and electrophysiology
Paulsen, P. A.; Jurkowski, Wiktor; Apostolov, R.; Lindahl, E.; Nissen, P.; Poulsen, H.

in Molecular Membrane Biology (2013), 30(2), 195-205

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See detailUnraveling genomic variation from next generation sequencing data
Pavlopoulos, Georgios A.; Oulas, Anastasis; Iacucci, Ernesto; Sifrim, Alejandro; Moreau, Yves; Schneider, Reinhard; Aerts, Jan; Iliopoulos, Ioannis

in BioData Mining (2013), 6(1), 13

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See detailPerformance tuning of applications for HPC systems employing Simulated Annealing optimization
Plugaru, Valentin; Georgatos, Fotis; Varrette, Sébastien; Bouvry, Pascal

Report (2013)

See detailIntegrated omics highlights keystone genes in community-wide metabolic networks
Roume, Hugo; Satagopam, Venkata; Muller, Emilie; May, Patrick; Hussong, René; Wilmes, Paul

Poster (2013)

See detailIntegrated omics highlights keystone genes in community-wide metabolic networks
Roume, Hugo; Satagopam, Venkata; Muller, Emilie; May, Patrick; Hussong, René; Wilmes, Paul

Poster (2013)

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See detailQuantitative analysis of colony morphology in yeast
Ruusuvuori, Pekka; Lin, Jake; Shmulevich, Ilya; Nykter, Matti; Scott, Adrian; Tan, Zhihao; Sorsa, Saija; Dudley, Aimee

in BioTechniques (2013)

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See detailPhenoTimer: Software for the Visual Mapping of Time-Resolved Phenotypic Landscapes
Secrier, Maria; Schneider, Reinhard

in PLoS ONE (2013), 8(8), 72361

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See detailVisualizing time-related data in biology, a review
Secrier, Maria; Schneider, Reinhard

in Briefings in Bioinformatics (2013)

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See detailNuclear calcium signaling in spinal neurons drives a genomic program required for persistent inflammatory pain
Simonetti, Manuela; Hagenston, Anna; Vardeh, Daniel; Freitag, Eckehard; Mauceri, Daniela; Lu, Jianning; Satagopam, Venkata; Schneider, Reinhard; Costigan, Michael; Bading, Hilmar; Kuner, Rohini

in Neuron (2013), 77(1), 43-57

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See detailNetwork deregulation analysis in complex diseases via the pairwise elastic net
Vlassis, Nikos; Glaab, Enrico

in Proc 8th BeNeLux Bioinformatics Conference (2013)

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2012

See detailStructural information involved in the interpretation of the stepwise protein folding process
Alejster, P.; Jurkowski, Wiktor; Roterman-Konieczna, I.

in Protein folding in silico : protein folding versus protein structure prediction (2012)

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See detailBioinformatics as a driver, not a passenger, of translational biomedical research: Perspectives from the 6th Benelux bioinformatics conference.
Azuaje, F. J.; Heymann, M.; Ternes, A. M.; Wienecke-Baldacchino, Anke; Struck, D.; Moes, D.; Schneider, Reinhard

in Journal of Clinical Bioinformatics (2012), 2(7),

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See detailFuzzy oil drop model to interpret the structure of antifreeze proteins and their mutants
Banach, Mateusz; Prymula, Katarzyna; Jurkowski, Wiktor; Konieczny, Leszek; Roterman, Irena

in Journal of Molecular Modeling (2012), 18(1), 229-237

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See detailExploring biological interaction networks with tailored weighted quasi-bicliques.
Chang, Wen-Chieh; Vakati, Sudheer; Krause, Roland; Eulenstein, Oliver

in BMC Bioinformatics (2012), 13 Suppl 10

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See detailHow Not to Be a Bioinformatician
Corpas, Manuel; Fatumo, Segun; Schneider, Reinhard

in Source Code for Biology and Medicine (2012)

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See detailGene regulatory network analysis supports inflammation as a key neurodegeneration process in prion disease.
Crespo, Isaac; Rump, Kirsten; Jurkowski, Wiktor; Kitano, H.; del Sol Mesa, Antonio

in BMC Systems Biology (2012), 6(132),

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See detailEnrichNet: network-based gene set enrichment analysis
Glaab, Enrico; Baudot, A.; Krasnogor, N.; Schneider, Reinhard; Valencia, A.

in Bioinformatics (2012), 28(18), 451-457

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See detailPLAU inferred from a correlation network is critical for suppressor function of regulatory T cells.
He, Feng; Chen, Hairong; Probst-Kepper, Michael; Geffers, Robert; Eifes, Serge; Del Sol, Antonio; Schughart, Klaus; Zeng, An-Ping; Balling, Rudi

in Molecular Systems Biology (2012), 8

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See detailReLiance: a machine learning and literature-based prioritization of receptor—ligand pairings.
Iacucci, Ernesto; Tranchevent, L. C.; Popovic, D.; Pavlopoulos, Georgios A.; De Moor, B.; Schneider, Reinhard; Moreau, Y.

in Bioinformatics (2012), 28(18), 569-574

See detailThe early-stage intermediate
Jurkowski, Wiktor; Baster, Z.; Dulak, D.; Roterman-Konieczna, I.

in Roterman-Konieczna, I. (Ed.) Protein Fold Silico Protein Fold Versus Protein Struct Predict (2012)

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See detailHuman gene correlation analysis (HGCA): A tool for the identification of transcriptionally co-expressed genes
Michalopoulos, Ioannis; Pavlopoulos, Georgios; Malatras, Apostolos; Karelas, Alexandros; Kostadima, Myrto-Areti; Schneider, Reinhard; Kossida, Sophia

in BMC Research Notes (2012), 5(265), 1-11

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See detailEvolutionary conservation and network structure characterize genes of phenotypic relevance for mitosis in human
Ostaszewski, Marek; Eifes, Serge; del Sol Mesa, Antonio

in PLoS ONE (2012), 7(5), 36488

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See detailDynamic regulation of microRNA expression following interferonγ- induced gene transcription
Reinsbach, Susanne; Nazarov, P. V.; Philippidou, Demetra; Schmitt, Michèle; Wienecke-Baldacchino, Anke; Muller, A.; Vallar, L.; Behrmann, Iris; Kreis, Stephanie

in RNA Biology (2012), 9(7), 987-989

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See detailEvaluation of detemir in diabetic cats managed with a protocol for intensive blood glucose control
Roomp, Kirsten; Rand, Jacquie

in Journal of Feline Medicine and Surgery (2012), 14(8), 566-572

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See detailPaving the future: finding suitable ISMB venues
Rost, B.; Gaasterland, T.; Lengauer, T.; Linial, M.; Markel, S.; McKay, B. J. M.; Schneider, Reinhard; Horton, P.; Kelso, J.

in Bioinformatics (2012), 28(19), 2556-9

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See detailComputation and Visualization of Protein Topology Graphs Including Ligand Information
Schäfer, Tim; May, Patrick; Koch, Ina

in Böcker, Sebasttian; Hufsky, Franziska; Scheubert, Kerstin; Schleicher, Jana; Schuster, Stefan (Eds.) German Conference on Bioinformatics 2012 (2012)

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See detailInterferon-γ-induced activation of Signal Transducer and Activator of Transcription 1 (STAT1) up-regulates the tumor suppressing microRNA-29 family in melanoma cells
Schmitt, Martina; Philippidou, Demetra; Reinsbach, Susanne; Margue, Christiane; Wienecke-Baldacchino, Anke; Nashan, D. C; Behrmann, Iris; Kreis, Stephanie

in Cell Communication and Signaling (2012), 10

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See detailGive It AGO: The Search for miRNA-Argonaute Sorting Signals in Arabidopsis thaliana Indicates a Relevance of Sequence Positions Other than the 5'-Position Alone.
Thieme, Christoph J.; Schudoma, Christian; May, Patrick; Walther, Dirk

in Frontiers in Plant Science (2012), 3

See detailConstructing a comprehensive map of Parkinson’s disease to elucidate underlying mechanisms of its multifaceted molecular pathology
Trefois, Christophe; Fujita, A. K.; Ostaszewski, Marek; Matsuoka, Yukiko; Ghosh, Samic; Glaab, Enrico; Crespo, Isaac; Perumal, T. M.; Jurkowski, Wiktor; Antony, Paul; Diederich, Nico; Buttini, Manuel; Kodama, Akihiko; Satagopam, Venkata; Eifes, Serge; del Sol Mesa, Antonio; Schneider, Reinhard; Kitano, Hiroaki; Balling, Rudi

Poster (2012, August)

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2011

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See detailPESCADOR, a web-based tool to assist text-mining of biointeractions extracted from PubMed queries.
Barbosa Da Silva, Adriano; Fontaine, Jean-Fred; Donnard, Elisa R.; Stussi, Fernanda; Ortega, J. Miguel; Andrade-Navarro, Miguel A.

in BMC bioinformatics (2011), 12

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See detailThe complement regulator CD46 is bactericidal to Helicobacter pylori and blocks urease activity
Basmarke-Wehelie, Rahma; Sjolinder, Hong; Jurkowski, Wiktor; Elofsson, Arne; Arnqvist, Anna; Engstrand, Lars; Hagner, Matthias; Wallin, Elin; Guan, Na; Kuranasekera, Hasanthi; Aro, Helena; Jonsson, Ann-Beth

in Gastroenterology (2011), 141(3), 918-28

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See detailValproic acid perturbs hematopoietic homeostasis by inhibition of erythroid differentiation and activation of the myelo-monocytic pathway
Chateauvieux, Sebastien; Eifes, Serge; Morceau, Franck; Grigorakaki, Christina; Schnekenburger, Michael; Henry, Estelle; Dicato, Mario; Diederich, Marc

in Biochemical Pharmacology (2011), 81(4), 498-509

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See detailPreimplantation development regulatory pathway construction through a text-mining approach.
Donnard, Elisa; Barbosa Da Silva, Adriano; Guedes, Rafael L. M.; Fernandes, Gabriel R.; Velloso, Henrique; Kohn, Matthew J.; Andrade-Navarro, Miguel A.; Ortega, J. Miguel

in BMC genomics (2011), 12 Suppl 4

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See detailGenie: literature-based gene prioritization at multi genomic scale.
Fontaine, Jean-Fred; Priller, Florian; Barbosa Da Silva, Adriano; Andrade-Navarro, Miguel A.

in Nucleic acids research (2011), 39(Web Server issue), 455-61

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See detailA low protein diet during early gestation in sheep detrimentally impacts hepatic glucose metabolism in the adult offspring
Gardner, David S.; Rhodes, Phillip; Karamitri, Angeliki; Glaab, Enrico; Rhind, Stuart M.

in Proceedings of the Nutrition Society 2011 (2011)

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See detailPPARγ population shift produces disease-related changes in molecular networks associated with metabolic syndrome
Jurkowski, Wiktor; Roomp, Kirsten; Crespo, Isaac; Schneider, Jochen; del Sol Mesa, Antonio

in Cell Death & Disease (2011), 2(8), 192

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See detailComparative analysis of miRNAs and their targets across four plant species.
Lenz, Dorina; May, Patrick; Walther, Dirk

in BMC Research Notes (2011), 4

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See detailWhich clustering algorithm is better for predicting protein complexes?
Moschopoulos, Charalampos N.; Pavlopoulos, Georgios A.; Iacucci, Ernesto; Aerts, Jan; Likothanassis, Spiridon; Schneider, Reinhard; Kossida, Sophia

in BMC Research Notes (2011), (4), 549

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See detailMedusa: A tool for exploring and clustering biological networks.
Pavlopoulos, Georgios A.; Hooper, S. D.; Sifrim, A.; Schneider, Reinhard; Aerts, Jan

in BMC Research Notes (2011), 4(1), 384

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See detailUsing graph theory to analyze biological networks
Pavlopoulos, Georgios A.; Secrier, Maria; Moschopoulos, Charalampos N.; Soldatos, Theodoros G.; Kossida, Sophia; Aerts, Jan; Schneider, Reinhard; Bagos, Pantelis G.

in BioData Mining (2011), 4(10), 1-27

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See detailTwo-intermediate model to characterize the structure of fast-folding proteins
Roterman, I.; Konieczny, L.; Jurkowski, Wiktor; Prymula, K.; Banach, M.

in Journal of Theoretical Biology (2011), 283(1), 60-70

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See detailIntermediates in the protein folding process: a computational model
Roterman, Irena; Konieczny, Leszek; Banach, Mateusz; Jurkowski, Wiktor

in International Journal of Molecular Sciences (2011), 12(8), 4850-60

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2010

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See detailLAITOR - Literature Assistant for Identification of Terms co-Occurrences and Relationships
Barbosa-Silva, Adriano; Soldatos, Theodoros G.; Magalhaes, Ivan L. F.; Pavlopoulos, Georgios A.; Fontaine, Jean-Fred; Andrade-Navarro, Miguel A.; Schneider, Reinhard; Ortega, J. Miguel

in BMC Bioinformatics (2010), 11(70),

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See detailFrom experimental setup to bioinformatics: An RNAi screening platform to identify host factors involved in HIV-1 replication
Boerner, Kathleen; Hermle, Johannes; Sommer, Christoph; Brown, Nigel P.; Knapp, Bettina; Glass, Baerbel; Kunkel, Julian; Torralba, Gloria; Reymann, Juergen; Beil, Nina; Beneke, Juergen; Pepperkok, Rainer; Schneider, Reinhard; Ludwig, Thomas; Hausmann, Michael; Hamprecht, Fred; Erfle, Holger; Kaderali, Lars; Kraeusslich, Hans-Georg; Lehmann, Maik J.

in Biotechnology Journal (2010), 5(1), 39-49

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See detailVisualization of omics data for systems biology
Gehlenborg, Nils; O'Donoghue, Sean I.; Baliga, Nitin S.; Goesmann, Alexander; Hibbs, Matthew A.; Kitano, Hiroaki; Kohlbacher, Oliver; Neuweger, Heiko; Schneider, Reinhard; Tenenbaum, Dan; Gavin, Anne-Claude

in Nature Methods (2010), 7(3), 56-68

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See detailA series of PDB related databases for everyday needs
Joosten, R.; Beek, T.; Krieger, E.; Hekkelman, M.; Hooft, R.; Schneider, Reinhard; Sander, S.; Vriend, G.

in Nucleic Acids Research (2010), 39(1), 411-419

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See detailLive Coverage of Intelligent Systems for Molecular Biology
Lister, Allyson L.; Datta, Ruchira S.; Hofmann, Oliver; Krause, Roland; Kuhn, Michael; Roth, Bettina; Schneider, Reinhard

in PLoS Computational Biology (2010), 6

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See detailLive Coverage of Scientific Conferences Using Web Technologies
Lister, Allyson L.; Datta, Ruchira S.; Hofmann, Oliver; Krause, Roland; Kuhn, Michael; Roth, Bettina; Schneider, Reinhard

in PLoS Computational Biology (2010), 6(1), 1-2

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See detailDefective Lamin A-Rb Signaling in Hutchinson-Gilford Progeria Syndrome and Reversal by Farnesyltransferase Inhibition
Marji, Jackleen; O'Donoghue, Sean I.; McClintock, Dayle; Satagopam, Venkata; Schneider, Reinhard; Ratner, Desiree; Worman, Howard J.; Gordon, Leslie B.; Djabali, Karima

in PLoS ONE (2010), 5(6),

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See detailPhenotypic profiling of the human genome by time-lapse microscopy reveals cell division genes
Neumann, Beate; Walter, Thomas; Heriche, Jean-Karim; Bulkescher, Jutta; Erfle, Holger; Conrad, Christian; Rogers, Phill; Poser, Ina; Held, Michael; Liebel, Urban; Cetin, Cihan; Sieckmann, Frank; Pau, Gregoire; Kabbe, Rolf; Wuensche, Annelie; Satagopam, Venkata; Schmitz, Michael H. A.; Chapuis, Catherine; Gerlich, Daniel W.; Schneider, Reinhard; Eils, Roland; Huber, Wolfgang; Peters, Jan-Michael; Hyman, Anthony A.; Durbin, Richard; Pepperkok, Rainer; Ellenberg, Jan

in Nature (2010), 464(7289), 721-727

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See detailReflect: A practical approach to web semantics
O'Donoghue, Sean I.; Horn, Heiko; Pafilis, Evangelos; Haag, Sven; Kuhn, Michael; Satagopam, Venkata; Schneider, Reinhard; Jensen, Lars J.

in Journal of Web Semantics (2010), 8(2-3), 182-189

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See detailA reference guide for tree analysis and visualization
Pavlopoulos, Georgios A.; Soldatos, Theodoros G.; Barbosa Da Silva, Adriano; Schneider, Reinhard

in BioData Mining (2010), 3

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See detailDetermining receptor-ligand interaction of human galanin receptor type 3
Runesson, Johan; Sollenberg, Ulla E.; Jurkowski, Wiktor; Yazdi, Samira; Eriksson, Einar E.; Elofsson, Arne; Langel, Ulo

in Neurochemistry International (2010), 57(7), 804-11

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See detailGPCRs, G-proteins, Effectors and their interactions: Human-gpDB, a database employing advanced visualization tools and data integration techniques
Satagopam, Venkata; Theodoropoulou, Margarita C.; Christos, Stampolakis K.; Pavlopoulos, Georgios A.; Papandreou, Nikolaos C.; Bagos, Pantelis G.; Schneider, Reinhard; Hamodrakas, Stavros J.

in Database (2010)

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See detailHeteronemin, a spongean sesterterpene, inhibits TNF alpha-induced NF-kappa B activation through proteasome inhibition and induces apoptotic cell death
Schumacher, Marc; Cerella, Claudia; Eifes, Serge; Chateauvieux, Sebastien; Morceau, Franck; Jaspars, Marcel; Dicato, Mario; Diederich, Marc

in Biochemical Pharmacology (2010), 79(4), 610-22

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See detailCurcumin-the paradigm of a multi-target natural compound with applications in cancer prevention and treatment
Teiten, Marie-Helene; Eifes, Serge; Dicato, Mario; Diederich, Marc

in Toxins (2010), 79(4), 128-62

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See detailChemopreventive potential of curcumin in prostate cancer
Teiten, Marie-Helene; Gaascht, Francois; Eifes, Serge; Dicato, Mario; Diederich, Marc

in Genes and Nutrition (2010), 5(1), 61-74

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2009

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See detailMedlineRanker: flexible ranking of biomedical literature.
Fontaine, Jean-Fred; Barbosa Da Silva, Adriano; Schaefer, Martin; Huska, Matthew R.; Muro, Enrique M.; Andrade-Navarro, Miguel A.

in Nucleic acids research (2009), 37(Web Server issue), 141-6

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See detailTumor necrosis factor alpha induces gamma-glutamyltransferase expression via nuclear factor-kappaB in cooperation with Sp1
Reuter, Simone; Schnekenburger, Michael; Cristofanon, Silvia; Buck, Isabelle; Teiten, Marie-Helene; Daubeuf, Sandrine; Eifes, Serge; Dicato, Mario; Aggarwal, Bharat B.; Visvikis, Athanase; Diederich, Marc

in Biochemical Pharmacology (2009), 77(3), 397-411

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See detailGene expression profiling related to anti-inflammatory properties of curcumin in K562 leukemia cells
Teiten, Marie-Helene; Eifes, Serge; Reuter, Simone; Duvoix, Annelyse; Dicato, Mario; Diederich, Marc

in Annals of the New York Academy of Sciences (2009), 1171

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