Home // LCSB // Research // Eco-Systems Biology

Eco-Systems Biology Group

The Eco-Systems Biology group at the LCSB

Paul Wilmes; Dominic Ternes ; Jean-Pierre Trezzi; Kacy Greenhalgh; Antoine Malabirade; Luise Kleine-Borgmann; Malte Herold; Javier Ramiro-Garcia; Cedric Christian Laczny. Front row (left to right): Rashi Halder; Susana Martinez Arbas; Deepti Mittal; Annegrät Daujeumont; Léa Grandmougin ; Janine Habier; Beatrice Yasmin Loulou Peisl. Not pictured: Joanna Baginska, Audrey Frachet-Bour, Laura Lebrun, Linda Wampach.

About the Eco-Systems Biology Group

We are embedded in a microbial world. Naturally occurring microbial communities play fundamental roles in the Earth’s biogeochemical cycles as well as in human health and disease, and provide essential services to mankind. Microbial consortia represent highly dynamic and heterogeneous systems, which exhibit enormous complexity at all levels.

We are using a Systems Biology approach to study mixed microbial communities in unprecedented detail. Microbial consortia of primary study include human host-associated microbiota and lipid accumulating microbial communities. Samples are routinely analysed in a systematic manner using integrated omics, comprising metagenomics, metatranscriptomics, metaproteomics and metabolomics. The resulting data is integrated and serves as input for the construction of multiscale models. The models allow formulation and testing of hypotheses which can be further validated using wet-lab experiments for example in a newly developed microfluidics-based human-microbial co-culture device and single-cell approaches.

Please consult our page regarding the individual research projects of the group.

The Eco-Systems Biology Research Group was established under the auspices of the Luxembourg National Research Fund's ATTRACT Programme.


Access the recommendation on F1000Prime

Head of Team

Dr. Paul Wilmes (LCSB)