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Immunology & Genetics

About the Immunology & Genetics group

The immune system is crucial for a health body function and protects us from severe infection. However, a dysregulated immunity can cause inflammation, autoimmune diseases and cancer. Especially, the control of immune cell metabolism as emerged as a powerful way to regulate immunity. The Brenner Lab investigates the metabolic regulation of the immune system and how this ensures a coordinated immune response and homeostasis. We seek to define the molecular, metabolic and cellular processes of inflammation and integrate in vitro with in vivo studies to gain a comprehensive picture of inflammation and cancer.

Schematic diagram of energy-generating metabolic pathways and their regulators. (Kurniawan, Soriano-Baguet, Brenner et al.)