Aurélien Ginolhac

A Ginolhac

Research scientist

Faculty or Centre Faculty of Science, Technology and Communication
Research Unit RU Life Sciences
Postal Address Université du Luxembourg
6, avenue du Swing
L-4367 Belvaux
Campus Office BioTech II, 4.22
Email
Telephone (+352) 46 66 44 6560
Fax (+352) 46 66 44 36560

Responsible of the Bioinformatic Core position at the Life Sciences Research Unit

Last updated on: Monday, 29 August 2016

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2019

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See detailIdentification of genes under dynamic post-transcriptional regulation from time-series epigenomic data
Becker, Julia Christina; Gerard, Déborah; Ginolhac, Aurélien; Sauter, Thomas; Sinkkonen, Lasse

in Epigenomics (2019)

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2018

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See detailTemporal enhancer profiling of parallel lineages identifies AHR and GLIS1 as regulators of mesenchymal multipotency
Gerard, Déborah; Schmidt, Florian; Ginolhac, Aurélien; Schmitz, Martine; Halder, Rashi; Ebert, Peter; Schulz, Marcel; Sauter, Thomas; Sinkkonen, Lasse

in Nucleic Acids Research (2018)

See detailUL HPC Tutorial: Statistical Computing with R
Ginolhac, Aurélien; Emeras, Joseph; Varrette, Sébastien; Plugaru, Valentin; Diehl, Sarah; Parisot, Clément; Cartiaux, Hyacinthe; Bouvry, Pascal

Presentation (2018, June)

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See detailCytokine-mediated modulation of the hepatic miRNome: miR-146b-5p is an IL-6-inducible miRNA with multiple targets.
Kirchmeyer, Melanie; Servais, Florence; Hamdorf, Matthias; Nazarov, Petr V.; Ginolhac, Aurélien; Halder, Rashi; Vallar, Laurent; Glanemann, Matthias; Rubie, Claudia; Lammert, Frank; Kreis, Stephanie; Behrmann, Iris

in Journal of leukocyte biology (2018)

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See detailTREM2 triggers microglial density and age‐related neuronal loss
Linnartz-Gerlach, Bettina; Bodea, Liviu-Gabriel; Klaus, Christine; Ginolhac, Aurélien; Halder, Rashi; Sinkkonen, Lasse; Walter, Jochen; Colonna, Marco; Neumann, Harald

in Glia (2018)

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See detailThe PD-L1- and IL6-mediated dampening of the IL27/STAT1 anticancer responses are prevented by a-PD-L1 or a-IL6 antibodies
Rolvering, Catherine; Zimmer, Andreas David; Ginolhac, Aurélien; Margue, Christiane; Kirchmeyer, Mélanie; Servais, Florence; Hermanns, Heike M.; Hergovits, Sabine; Nazarov, Petr V.; Nicot, Nathalie; Kreis, Stephanie; Haan, Serge; Behrmann, Iris; Haan, Claude

in Journal of Leukocyte Biology (2018), 104

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See detailThe microRNA-371~373 cluster represses colon cancer initiation and metastatic colonization by inhibiting the TGFBR2/ID1 signaling axis.
Ullmann, Pit; Rodriguez, Fabien; Schmitz, Martine; Meurer, Steffen K.; Qureshi-Baig, Komal; Felten, Paul; Ginolhac, Aurélien; Antunes, Laurent; Frasquilho, Sonia; Zugel, Nikolaus; Weiskirchen, Ralf; Haan, Serge; Letellier, Elisabeth

in Cancer research (2018)

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2017

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See detailLoss of Myosin Vb in colorectal cancer is a strong prognostic factor for disease recurrence
Letellier, Elisabeth; Schmitz, Martine; Ginolhac, Aurélien; Rodriguez, Fabien; Ullmann, Pit; Qureshi-Baig, Komal; Frasquilho, Sonia; Antunes, Laurent; Haan, Serge

in British Journal of Cancer (2017), 117(11), 1689-1701

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See detailCrosstalk between different family members: IL27 recapitulates IFNγ responses in HCC cells, but is inhibited by IL6-type cytokines
Rolvering, Catherine; Zimmer, Andreas; Kozar, Ines; Hermanns; Letellier, Elisabeth; Vallar, Laurent; Nazarov, Petr; Nicot, Nathalie; Ginolhac, Aurélien; Haan, Serge; Behrmann, Iris; Haan, Claude

in BBA Molecular Cell Research (2017)

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2016

See detail“Melanomics”: analysis and integration of whole genomes, transcriptomes and miRNomes of primary melanoma patients
Reinsbach, Susanne; Wienecke, Anke; Ginolhac, Aurélien; Vallar, Laurent; Krishna; Krishna, Abhimanyu; Nazarov, Petr; May, Patrick; Kreis, Stephanie

in European Journal of Cancer (2016), 61(Suppl.1), 32

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See detailHypoxia-responsive miR-210 promotes self-renewal capacity of colon tumor-initiating cells by repressing ISCU and by inducing lactate production
Ullmann, Pit; qureshi-baig, komal; Rodriguez, Fabien; Ginolhac, Aurélien; nonnenmacher, yannic; Ternes, Dominik; Weiler, Jil; Gaebler, Karoline; bahlawane, Christelle; hiller, karsten; Haan, Serge; Letellier, Elisabeth

in Oncotarget (2016)

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2015

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See detailEvolutionary Genomics and Conservation of the Endangered Przewalski's Horse.
Der Sarkissian, Clio; Ermini, Luca; Schubert, Mikkel; Yang, Melinda A.; Librado, Pablo; Fumagalli, Matteo; Jonsson, Hakon; Bar-Gal, Gila Kahila; Albrechtsen, Anders; Vieira, Filipe G.; Petersen, Bent; Ginolhac, Aurélien; Seguin-Orlando, Andaine; Magnussen, Kim; Fages, Antoine; Gamba, Cristina; Lorente-Galdos, Belen; Polani, Sagi; Steiner, Cynthia; Neuditschko, Markus; Jagannathan, Vidhya; Feh, Claudia; Greenblatt, Charles L.; Ludwig, Arne; Abramson, Natalia I.; Zimmermann, Waltraut; Schafberg, Renate; Tikhonov, Alexei; Sicheritz-Ponten, Thomas; Willerslev, Eske; Marques-Bonet, Tomas; Ryder, Oliver A.; McCue, Molly; Rieder, Stefan; Leeb, Tosso; Slatkin, Montgomery; Orlando, Ludovic

in Current Biology (2015), 25(19), 2577-83

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See detailRole of Calprotectin as a Modulator of the IL27-Mediated Proinflammatory Effect on Endothelial Cells
Dorosz, Susann Antonia; Ginolhac, Aurélien; Kähne, Thilo; Naumann, Michael; Sauter, Thomas; Salsmann, Alexandre; Bueb, Jean-Luc

in Mediators of Inflammation (2015), 2015

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2014

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See detailSpeciation with gene flow in equids despite extensive chromosomal plasticity.
Jonsson, Hakon; Schubert, Mikkel; Seguin-Orlando, Andaine; Ginolhac, Aurélien; Petersen, Lillian; Fumagalli, Matteo; Albrechtsen, Anders; Petersen, Bent; Korneliussen, Thorfinn S.; Vilstrup, Julia T.; Lear, Teri; Myka, Jennifer Leigh; Lundquist, Judith; Miller, Donald C.; Alfarhan, Ahmed H.; Alquraishi, Saleh A.; Al-Rasheid, Khaled A. S.; Stagegaard, Julia; Strauss, Gunter; Bertelsen, Mads Frost; Sicheritz-Ponten, Thomas; Antczak, Douglas F.; Bailey, Ernest; Nielsen, Rasmus; Willerslev, Eske; Orlando, Ludovic

in Proceedings of the National Academy of Sciences of the United States of America (2014), 111(52), 18655-60

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See detailCharacterization of ancient and modern genomes by SNP detection and phylogenomic and metagenomic analysis using PALEOMIX.
Schubert, Mikkel; Ermini, Luca; Der Sarkissian, Clio; Jonsson, Hakon; Ginolhac, Aurélien; Schaefer, Robert; Martin, Michael D.; Fernandez, Ruth; Kircher, Martin; McCue, Molly; Willerslev, Eske; Orlando, Ludovic

in Nature protocols (2014), 9(5), 1056-82

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See detailPrehistoric genomes reveal the genetic foundation and cost of horse domestication.
Schubert, Mikkel; Jonsson, Hakon; Chang, Dan; Der Sarkissian, Clio; Ermini, Luca; Ginolhac, Aurélien; Albrechtsen, Anders; Dupanloup, Isabelle; Foucal, Adrien; Petersen, Bent; Fumagalli, Matteo; Raghavan, Maanasa; Seguin-Orlando, Andaine; Korneliussen, Thorfinn S.; Velazquez, Amhed M. V.; Stenderup, Jesper; Hoover, Cindi A.; Rubin, Carl-Johan; Alfarhan, Ahmed H.; Alquraishi, Saleh A.; Al-Rasheid, Khaled A. S.; MacHugh, David E.; Kalbfleisch, Ted; MacLeod, James N.; Rubin, Edward M.; Sicheritz-Ponten, Thomas; Andersson, Leif; Hofreiter, Michael; Marques-Bonet, Tomas; Gilbert, M. Thomas P.; Nielsen, Rasmus; Excoffier, Laurent; Willerslev, Eske; Shapiro, Beth; Orlando, Ludovic

in Proceedings of the National Academy of Sciences of the United States of America (2014), 111(52), 5661-9

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2013

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See detailmapDamage2.0: fast approximate Bayesian estimates of ancient DNA damage parameters.
Jonsson, Hakon; Ginolhac, Aurélien; Schubert, Mikkel; Johnson, Philip L. F.; Orlando, Ludovic

in Bioinformatics (Oxford, England) (2013), 29(13), 1682-4

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See detailRecalibrating Equus evolution using the genome sequence of an early Middle Pleistocene horse.
Orlando, Ludovic; Ginolhac, Aurélien; Zhang, Guojie; Froese, Duane; Albrechtsen, Anders; Stiller, Mathias; Schubert, Mikkel; Cappellini, Enrico; Petersen, Bent; Moltke, Ida; Johnson, Philip L. F.; Fumagalli, Matteo; Vilstrup, Julia T.; Raghavan, Maanasa; Korneliussen, Thorfinn; Malaspinas, Anna-Sapfo; Vogt, Josef; Szklarczyk, Damian; Kelstrup, Christian D.; Vinther, Jakob; Dolocan, Andrei; Stenderup, Jesper; Velazquez, Amhed M. V.; Cahill, James; Rasmussen, Morten; Wang, Xiaoli; Min, Jiumeng; Zazula, Grant D.; Seguin-Orlando, Andaine; Mortensen, Cecilie; Magnussen, Kim; Thompson, John F.; Weinstock, Jacobo; Gregersen, Kristian; Roed, Knut H.; Eisenmann, Vera; Rubin, Carl J.; Miller, Donald C.; Antczak, Douglas F.; Bertelsen, Mads F.; Brunak, Soren; Al-Rasheid, Khaled A. S.; Ryder, Oliver; Andersson, Leif; Mundy, John; Krogh, Anders; Gilbert, M. Thomas P.; Kjaer, Kurt; Sicheritz-Ponten, Thomas; Jensen, Lars Juhl; Olsen, Jesper V.; Hofreiter, Michael; Nielsen, Rasmus; Shapiro, Beth; Wang, Jun; Willerslev, Eske

in Nature (2013), 499(7456), 74-8

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See detailMitochondrial phylogenomics of modern and ancient equids.
Vilstrup, Julia T.; Seguin-Orlando, Andaine; Stiller, Mathias; Ginolhac, Aurélien; Raghavan, Maanasa; Nielsen, Sandra C. A.; Weinstock, Jacobo; Froese, Duane; Vasiliev, Sergei K.; Ovodov, Nikolai D.; Clary, Joel; Helgen, Kristofer M.; Fleischer, Robert C.; Cooper, Alan; Shapiro, Beth; Orlando, Ludovic

in PloS one (2013), 8(2), 55950

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2012

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See detailProteomic analysis of a pleistocene mammoth femur reveals more than one hundred ancient bone proteins.
Cappellini, Enrico; Jensen, Lars J.; Szklarczyk, Damian; Ginolhac, Aurélien; da Fonseca, Rute A. R.; Stafford, Thomas W.; Holen, Steven R.; Collins, Matthew J.; Orlando, Ludovic; Willerslev, Eske; Gilbert, M. Thomas P.; Olsen, Jesper V.

in Journal of proteome research (2012), 11(2), 917-26

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See detailImproving the performance of true single molecule sequencing for ancient DNA.
Ginolhac, Aurélien; Vilstrup, Julia; Stenderup, Jesper; Rasmussen, Morten; Stiller, Mathias; Shapiro, Beth; Zazula, Grant; Froese, Duane; Steinmann, Kathleen E.; Thompson, John F.; Al-Rasheid, Khaled A. S.; Gilbert, Thomas M. P.; Willerslev, Eske; Orlando, Ludovic

in BMC genomics (2012), 13

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See detailImproving ancient DNA read mapping against modern reference genomes.
Schubert, Mikkel; Ginolhac, Aurélien; Lindgreen, Stinus; Thompson, John F.; Al-Rasheid, Khaled A. S.; Willerslev, Eske; Krogh, Anders; Orlando, Ludovic

in BMC genomics (2012), 13

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2011

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See detailmapDamage: testing for damage patterns in ancient DNA sequences.
Ginolhac, Aurélien; Rasmussen, Morten; Gilbert, M. Thomas P.; Willerslev, Eske; Orlando, Ludovic

in Bioinformatics (Oxford, England) (2011), 27(15), 2153-5

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See detailTrue single-molecule DNA sequencing of a pleistocene horse bone.
Orlando, Ludovic; Ginolhac, Aurélien; Raghavan, Maanasa; Vilstrup, Julia; Rasmussen, Morten; Magnussen, Kim; Steinmann, Kathleen E.; Kapranov, Philipp; Thompson, John F.; Zazula, Grant; Froese, Duane; Moltke, Ida; Shapiro, Beth; Hofreiter, Michael; Al-Rasheid, Khaled A. S.; Gilbert, M. Thomas P.; Willerslev, Eske

in Genome research (2011), 21(10), 1705-19

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