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Maria Pires Pacheco

Maria Pires Pacheco

Postdoctoral researcher

Faculty or Centre Faculty of Science, Technology and Medicine
Department Department of Life Sciences and Medicine
Postal Address Université du Luxembourg
6, avenue du Swing
L-4367 Belvaux
Campus Office BioTech II Ketterthill, 4.11
Email
Telephone (+352) 46 66 44 9969
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2022

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See detailBruceine D Identified as a Drug Candidate against Breast Cancer by a Novel Drug Selection Pipeline and Cell Viability Assay.
Cipriani, Claudia; Pires Pacheco, Maria Irene; Kishk, Ali; Wachich, Maryem; Abankwa, Daniel; Schaffner-Reckinger, Elisabeth; Sauter, Thomas

in Pharmaceuticals (Basel, Switzerland) (2022), 15(2),

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See detailIntegration of external biomass reactions into existing metabolic models
Moscardo Garcia, Maria; Pires Pacheco, Maria Irene; Sauter, Thomas

E-print/Working paper (2022)

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See detailProject-based learning course on metabolic network modelling in computational systems biology.
Sauter, Thomas; Bintener, Tamara; Kishk, Ali; Presta, Luana; Prohaska, Tessy; Guignard, Daniel; Zeng, Ni; Cipriani, Claudia; Arshad, Sundas; Pfau, Thomas; Martins Conde, Patricia; Pires Pacheco, Maria Irene

in PLoS computational biology (2022), 18(1), 1009711

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See detailThe gut microbial metabolite formate exacerbates colorectal cancer progression
Ternes, Dominik; Tsenkova, Mina; Pozdeev, Vitaly; Meyers, Marianne; Koncina, Eric; Atatri, Sura; Schmitz, Martine; Karta, Jessica; Schmoetten, Maryse; Heinken, Almut; Rodriguez, Fabien; Delbrouck, Catherine; Gaigneaux, Anthoula; Ginolhac, Aurélien; Dan Nguyen, Tam Thuy; Grandmougin, Lea; Frachet-Bour, Audrey; Martin-Gallausiaux, Camille; Pires Pacheco, Maria Irene; Neuberger-Castillo, Lorie; Miranda, Paulo; Zuegel, Nikolaus; Ferrand, Jean-Yves; Gantenbein, Manon; Sauter, Thomas; Slade, Daniel Joseph; Thiele, Ines; Meiser, Johannes; Haan, Serge; Wilmes, Paul; Letellier, Elisabeth

in Nature Metabolism (2022)

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2021

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See detailLoss of Ambra1 promotes melanoma growth and invasion.
Di Leo, Luca; Bodemeyer, Valérie; Bosisio, Francesca M.; Claps, Giuseppina; Carretta, Marco; Rizza, Salvatore; Faienza, Fiorella; Frias, Alex; Khan, Shawez; Bordi, Matteo; Pires Pacheco, Maria Irene; Di Martino, Julie; Bravo-Cordero, Jose J.; Daniel, Colin J.; Sears, Rosalie C.; Donia, Marco; Madsen, Daniel H.; Guldberg, Per; Filomeni, Giuseppe; Sauter, Thomas; Robert, Caroline; De Zio, Daniela; Cecconi, Francesco

in Nature communications (2021), 12(1), 2550

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See detailDCcov: Repositioning of drugs and drug combinations for SARS-CoV-2 infected lung through constraint-based modeling.
Kishk, Ali; Pires Pacheco, Maria Irene; Sauter, Thomas

in iScience (2021), 24(11), 103331

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See detailA dynamic multi-tissue model to study human metabolism.
Martins Conde, Patricia; Pfau, Thomas; Pires Pacheco, Maria Irene; Sauter, Thomas

in NPJ systems biology and applications (2021), 7(1), 5

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See detailImportance of the biomass formulation for cancer metabolic modeling and drug prediction.
Moscardo Garcia, Maria; Pires Pacheco, Maria Irene; Bintener, Tamara Jean Rita; Presta, Luana; Sauter, Thomas

in iScience (2021), 24(10), 103110

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2020

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See detailTowards the routine use of in silico screenings for drug discovery using metabolic modelling
Bintener, Tamara Jean Rita; Pires Pacheco, Maria Irene; Sauter, Thomas

in Biochemical Society Transactions (2020)

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See detailTesting informed SIR based epidemiological model for COVID-19 in Luxembourg
Sauter, Thomas; Pires Pacheco, Maria Irene

E-print/Working paper (2020)

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2019

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See detailIntegrated In Vitro and In Silico Modeling Delineates the Molecular Effects of a Synbiotic Regimen on Colorectal-Cancer-Derived Cells
Greenhalgh, Kacy; Ramiro Garcia, Javier; Heinken; Ullmann, Pit; Bintener, Tamara Jean Rita; Pacheco, Maria; Baginska, joanna; Shah, Pranjul; Frachet Bour, Audrey; Halder, Rashi; Fritz, Joëlle; Sauter, Thomas; Thiele, Ines; Haan, Serge; Letellier, Elisabeth; Wilmes, Paul

in Cell Reports (2019), 27

See detailTowards the Integration of Metabolic Network Modelling and Machine Learning for the Routine Analysis of High-Throughput Patient Data
Pacheco, Maria; Bintener, Tamara Jean Rita; Sauter, Thomas

in Automated Reasoning for Systems Biology and Medicine (2019)

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See detailTowards the network-based prediction of repurposed drugs using patient-specific metabolic models.
Pacheco, Maria; Bintener, Tamara Jean Rita; Sauter, Thomas

in EBioMedicine (2019)

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See detailIdentifying and targeting cancer-specific metabolism with network-based drug target prediction
Pacheco, Maria; Bintener, Tamara Jean Rita; Ternes, Dominik; Kulms, Dagmar; Haan, Serge; Letellier, Elisabeth; Sauter, Thomas

in EBioMedicine (2019), 43(May 2019), 98-106

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See detailThe Power of LC-MS Based Multiomics: Exploring Adipogenic Differentiation of Human Mesenchymal Stem/Stromal Cells
Rampler, Evelyn; Egger, Dominik; Schoeny, Harald; Rusz, Mate; Pacheco, Maria; Marino, Giada; Kasper, Cornelia; Koellensperger, Gunda

in Molecules (2019)

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2018

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See detailThe FASTCORE Family: For the Fast Reconstruction of Compact Context-Specific Metabolic Networks Models
Pacheco, Maria; Sauter, Thomas

in Fondi, Marco (Ed.) Metabolic Network Reconstruction and Modeling (2018)

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See detailThe FASTCORE Family: For the Fast Reconstruction of Compact Context-Specific Metabolic Networks Models.
Pacheco, Maria; Sauter, Thomas

in Methods in Molecular Biology (2018), (1716), 101-110

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2016

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See detailBenchmarking procedures for high-throughput context specific reconstruction algorithms
Pacheco, Maria; Pfau, Thomas; Sauter, Thomas

in Frontiers in Physiology (2016)

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2015

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See detailThe neural stem cell fate determinant TRIM32 regulates complex behavioral traits
Hillje, Anna-Lena; Beckmann, Elisabeth; Pavlou, Maria Angeliki; Jäger, Christian; Pacheco, Maria; Sauter, Thomas; Schwamborn, Jens Christian; Lewejohann, Lars

in Frontiers in Cellular Neuroscience (2015)

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See detailIntegrated metabolic modelling reveals cell-type specific epigenetic control points of the macrophage metabolic network
Pacheco, Maria; John, Elisabeth; Kaoma, Tony; Heinäniemi, Merja; Nicot, Nathalie; Vallar, Laurent; Bueb, Jean-Luc; Sinkkonen, Lasse; Sauter, Thomas

in BMC Genomics (2015), 16(809),

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See detailTowards improved genome-scale metabolic network reconstructions: unification, transcript specificity and beyond.
Pfau, Thomas; Pacheco, Maria; Sauter, Thomas

in Briefings in bioinformatics (2015)

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2014

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See detailFast reconstruction of compact context-specific metabolic network models
Vlassis, Nikos; Pacheco, Maria; Sauter, Thomas

in PLoS Computational Biology (2014), 10(1), 1003424

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2013

See detailFast reconstruction of compact context-specific metabolic network models
Vlassis, Nikos; Pacheco, Maria; Sauter, Thomas

E-print/Working paper (2013)

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See detailFastcore: An algorithm for fast reconstruction of context-specific metabolic network models
Vlassis, Nikos; Pacheco, Maria; Sauter, Thomas

in Proc. 8th BeNeLux Bioinformatics Conference (2013)

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