Prof. Dr. Thomas Sauter

Thomas Sauter

Full professor in Systems biology

Research Topics Systems Biology
Faculty or Centre Faculty of Science, Technology and Medicine
Department Department of Life Sciences and Medicine
Postal Address Université du Luxembourg
6, avenue du Swing
L-4367 Belvaux
Campus Office BioTech II Ketterthill, 4.13
Email
Telephone (+352) 46 66 44 6296
Fax (+352) 46 66 44 6435

Last updated on: Monday, 14 June 2021

powered by
orbilu.uni.lu

2021

Full Text
See detailDegree Adjusted Large-Scale Network Analysis Reveals Novel Putative Metabolic Disease Genes.
Badkas, Apurva; Nguyen, Thanh-Phuong; Caberlotto, Laura; Schneider, Jochen; De Landtsheer, Sébastien; Sauter, Thomas

in Biology (2021), 10(2),

Full Text
See detailLoss of Ambra1 promotes melanoma growth and invasion.
Di Leo, Luca; Bodemeyer, Valérie; Bosisio, Francesca M.; Claps, Giuseppina; Carretta, Marco; Rizza, Salvatore; Faienza, Fiorella; Frias, Alex; Khan, Shawez; Bordi, Matteo; Pires Pacheco, Maria Irene; Di Martino, Julie; Bravo-Cordero, Jose J.; Daniel, Colin J.; Sears, Rosalie C.; Donia, Marco; Madsen, Daniel H.; Guldberg, Per; Filomeni, Giuseppe; Sauter, Thomas; Robert, Caroline; De Zio, Daniela; Cecconi, Francesco

in Nature communications (2021), 12(1), 2550

Full Text
See detailL-plastin Ser5 phosphorylation is modulated by the PI3K/SGK pathway and promotes breast cancer cell invasiveness
Machado, Raquel A.C.; Stojevski, Dunja; de Landtsheer, Sébastien; Lucarelli, Philippe; Baron, Alexandre; Sauter, Thomas; Schaffner-Reckinger, Elisabeth

in Cell Communication and Signaling (2021), 19(22), 1-22

Full Text
See detailA dynamic multi-tissue model to study human metabolism.
Martins Conde, Patricia; Pfau, Thomas; Pires Pacheco, Maria Irene; Sauter, Thomas

in NPJ systems biology and applications (2021), 7(1), 5

Full Text
See detailIDARE2-Simultaneous Visualisation of Multiomics Data in Cytoscape.
Pfau, Thomas; Galhardo, Mafalda; Lin, Jake; Sauter, Thomas

in Metabolites (2021), 11(5),

Top of Page

2020

Full Text
See detailComputational models of melanoma.
Albrecht, Marco; Lucarelli, Philippe; Kulms, Dagmar; Sauter, Thomas

in Theoretical biology & medical modelling (2020), 17(1), 8

Full Text
See detailTopological network measures for drug repositioning.
Badkas, Apurva; De Landtsheer, Sébastien; Sauter, Thomas

in Briefings in bioinformatics (2020)

Full Text
See detailTowards the routine use of in silico screenings for drug discovery using metabolic modelling
Bintener, Tamara Jean Rita; Pires Pacheco, Maria Irene; Sauter, Thomas

in Biochemical Society Transactions (2020)

Full Text
See detailPituitary Tumor Transforming Gene 1 Orchestrates Gene Regulatory Variation in Mouse Ventral Midbrain During Aging
Gui, Yujuan; Thomas, Mélanie H.; Garcia, Pierre; Karout, Mona; Halder, Rashi; Michelucci, Alessandro; Kollmus, Heike; Zhou, Cuiqi; Melmed, Shlomo; Schughart, Klaus; Balling, Rudolf; Mittelbronn, Michel; Nadeau, Joseph H.; Williams, Robert W.; Sauter, Thomas; Buttini, Manuel; Sinkkonen, Lasse

in Frontiers in Genetics (2020)

Full Text
See detailReduced sialylation triggers homeostatic synapse and neuronal loss in middle-aged mice
Klaus, Christine; Hansen, Jan N.; Ginolhac, Aurélien; Gérard, Deborah; Gnanapragassam, Vinayaga S.; Horstkorte, Rüdiger; Rossdam, Charlotte; Buettner, Falk F. R.; Sauter, Thomas; Sinkkonen, Lasse; Neumann, Harald; Linnartz-Gerlach, Bettina

in Neurobiology of Aging (2020)

Full Text
See detailAn efficient machine learning-based approach for screening individuals at risk of hereditary haemochromatosis.
Martins Conde, Patricia; Sauter, Thomas; Nguyen, Thanh-Phuong

in Scientific reports (2020), 10(1), 20613

Full Text
See detailCancer Cells Employ Nuclear Caspase-8 to Overcome the p53-Dependent G2/M Checkpoint through Cleavage of USP28.
Muller, Ines; Strozyk, Elwira; Schindler, Sebastian; Beissert, Stefan; Oo, Htoo Zarni; Sauter, Thomas; Lucarelli, Philippe; Raeth, Sebastian; Hausser, Angelika; Al Nakouzi, Nader; Fazli, Ladan; Gleave, Martin E.; Liu, He; Simon, Hans-Uwe; Walczak, Henning; Green, Douglas R.; Bartek, Jiri; Daugaard, Mads; Kulms, Dagmar

in Molecular cell (2020)

Full Text
See detailTesting informed SIR based epidemiological model for COVID-19 in Luxembourg
Sauter, Thomas; Pires Pacheco, Maria Irene

E-print/Working paper (2020)

Top of Page

2019

Full Text
See detailClinical update on head and neck cancer: molecular biology and ongoing challenges.
Alsahafi, Elham; Begg, Katheryn; Amelio, Ivano; Raulf, Nina; Lucarelli, Philippe; Sauter, Thomas; Tavassoli, Mahvash

in Cell death & disease (2019), 10(8), 540

Full Text
See detailIdentification of genes under dynamic post-transcriptional regulation from time-series epigenomic data
Becker, Julia Christina; Gerard, Déborah; Ginolhac, Aurélien; Sauter, Thomas; Sinkkonen, Lasse

in Epigenomics (2019)

Full Text
See detailAn Efficient Machine Learning Method to Solve Imbalanced Data in Metabolic Disease Prediction
Cecchini, Vania Filipa; Nguyen, Thanh-Phuong; Pfau, Thomas; De Landtsheer, Sébastien; Sauter, Thomas

in Cecchini, Vania Filipa (Ed.) An Efficient Machine Learning Method to Solve Imbalanced Data in Metabolic Disease Prediction (2019)

Full Text
See detailIntegrated In Vitro and In Silico Modeling Delineates the Molecular Effects of a Synbiotic Regimen on Colorectal-Cancer-Derived Cells
Greenhalgh, Kacy; Ramiro Garcia, Javier; Heinken; Ullmann, Pit; Bintener, Tamara Jean Rita; Pacheco, Maria; Baginska, joanna; Shah, Pranjul; Frachet Bour, Audrey; Halder, Rashi; Fritz, Joëlle; Sauter, Thomas; Thiele, Ines; Haan, Serge; Letellier, Elisabeth; Wilmes, Paul

in Cell Reports (2019), 27

Full Text
See detailCreation and analysis of biochemical constraint-based models using the COBRA Toolbox v.3.0.
Heirendt, Laurent; Arreckx, Sylvain; Pfau, Thomas; Mendoza, Sebastian N.; Richelle, Anne; Heinken, Almut Katrin; Haraldsdottir, Hulda S.; Wachowiak, Jacek; Keating, Sarah M.; Vlasov, Vanja; Magnusdottir, Stefania; Ng, Chiam Yu; Preciat, German; Zagare, Alise; Chan, Siu H. J.; Aurich, Maike K.; Clancy, Catherine M.; Modamio, Jennifer; Sauls, John T.; Noronha, Alberto; Bordbar, Aarash; Cousins, Benjamin; El Assal, Diana Charles; Valcarcel, Luis V.; Apaolaza, Inigo; Ghaderi, Susan; Ahookhosh, Masoud; Ben Guebila, Marouen; Kostromins, Andrejs; Sompairac, Nicolas; Le, Hoai M.; Ma, Ding; Sun, Yuekai; Wang, Lin; Yurkovich, James T.; Oliveira, Miguel A. P.; Vuong, Phan T.; El Assal, Lemmer P.; Kuperstein, Inna; Zinovyev, Andrei; Hinton, H. Scott; Bryant, William A.; Aragon Artacho, Francisco J.; Planes, Francisco J.; Stalidzans, Egils; Maass, Alejandro; Vempala, Santosh; Hucka, Michael; Saunders, Michael A.; Maranas, Costas D.; Lewis, Nathan E.; Sauter, Thomas; Palsson, Bernhard O.; Thiele, Ines; Fleming, Ronan M. T.

in Nature protocols (2019), 14(3), 639-702

Full Text
See detailImpaired serine metabolism complements LRRK2-G2019S pathogenicity in PD patients
Nickels, Sarah; Walter, Jonas; Bolognin, Silvia; Gerard, Deborah; Jäger, Christian; Qing, Xiaobing; Tisserand, Johan; Jarazo, Javier; Hemmer, Kathrin; Harms, Amy; Halder, Rashi; Lucarelli, Philippe; Berger, Emanuel; Antony, Paul; Glaab, Enrico; Hankemeier, Thomas; Klein, Christine; Sauter, Thomas; Sinkkonen, Lasse; Schwamborn, Jens Christian

in Parkinsonism and Related Disorders (2019)

See detailTowards the Integration of Metabolic Network Modelling and Machine Learning for the Routine Analysis of High-Throughput Patient Data
Pacheco, Maria; Bintener, Tamara Jean Rita; Sauter, Thomas

in Automated Reasoning for Systems Biology and Medicine (2019)

Full Text
See detailTowards the network-based prediction of repurposed drugs using patient-specific metabolic models.
Pacheco, Maria; Bintener, Tamara Jean Rita; Sauter, Thomas

in EBioMedicine (2019)

Full Text
See detailIdentifying and targeting cancer-specific metabolism with network-based drug target prediction
Pacheco, Maria; Bintener, Tamara Jean Rita; Ternes, Dominik; Kulms, Dagmar; Haan, Serge; Letellier, Elisabeth; Sauter, Thomas

in EBioMedicine (2019), 43(May 2019), 98-106

Top of Page

2018

Full Text
See detailUsing Regularization to Infer Cell Line Specificity in Logical Network Models of Signaling Pathways.
De Landtsheer, Sébastien; Lucarelli, Philippe; Sauter, Thomas

in Frontiers in physiology (2018), 9

Full Text
See detailSystemic network analysis identifies XIAP and IkappaBalpha as potential drug targets in TRAIL resistant BRAF mutated melanoma.
Del Mistro, Greta; Lucarelli, Philippe; Muller, Ines; De Landtsheer, Sébastien; Zinoveva, Anna; Hutt, Meike; Siegemund, Martin; Kontermann, Roland E.; Beissert, Stefan; Sauter, Thomas; Kulms, Dagmar

in NPJ systems biology and applications (2018), 4

Full Text
See detailTemporal enhancer profiling of parallel lineages identifies AHR and GLIS1 as regulators of mesenchymal multipotency
Gerard, Déborah; Schmidt, Florian; Ginolhac, Aurélien; Schmitz, Martine; Halder, Rashi; Ebert, Peter; Schulz, Marcel; Sauter, Thomas; Sinkkonen, Lasse

in Nucleic Acids Research (2018)

Full Text
See detailThe FASTCORE Family: For the Fast Reconstruction of Compact Context-Specific Metabolic Networks Models
Pacheco, Maria; Sauter, Thomas

in Fondi, Marco (Ed.) Metabolic Network Reconstruction and Modeling (2018)

Full Text
See detailThe FASTCORE Family: For the Fast Reconstruction of Compact Context-Specific Metabolic Networks Models.
Pacheco, Maria; Sauter, Thomas

in Methods in Molecular Biology (Clifton, N.J.) (2018), (1716), 101-110

Full Text
See detailAnnexin A1 regulates EGFR activity and alters EGFR-containing tumour-derived exosomes in head and neck cancers.
Raulf, N.; Lucarelli, Philippe; Thavaraj, S.; Brown, S.; Vicencio, J. M.; Sauter, Thomas; Tavassoli, M.

in European journal of cancer (Oxford, England : 1990) (2018), 102

Full Text
See detailPhosphoprotein patterns predict trametinib responsiveness and optimal trametinib sensitisation strategies in melanoma.
Rozanc, Jan; Sakellaropoulos, Theodore; Antoranz, Asier; Gutta, Cristiano; Podder, Biswajit; Vetma, Vesna; Rufo, Nicole; Agostinis, Patrizia; Pliaka, Vaia; Sauter, Thomas; Kulms, Dagmar; Rehm, Markus; Alexopoulos, Leonidas G.

in Cell death and differentiation (2018)

Full Text
See detail"Stroma-induced phenotypic plasticity offers phenotype-specific targeting to improve melanoma treatment".
Seip, Kotryna; Jorgensen, Kjetil; Haselager, Marco Vincent; Albrecht, Marco; Haugen, Mads Haugland; Egeland, Eivind Valen; Lucarelli, Philippe; Engebraaten, Olav; Sauter, Thomas; Maelandsmo, Gunhild Mari; Prasmickaite, Lina

in Cancer letters (2018)

Top of Page

2017

Full Text
See detailFALCON: A Toolbox for the Fast Contextualisation of Logical Networks.
De Landtsheer, Sébastien; Trairatphisan, Panuwat; Lucarelli, Philippe; Sauter, Thomas

in Bioinformatics (Oxford, England) (2017)

Full Text
See detailSystembasierte Analyse von Wirkstoffresistenzen bei Melanom
Lucarelli, Philippe; De Landtsheer, Sébastien; Sauter, Thomas

E-print/Working paper (2017)

Top of Page

2016

Full Text
See detailThermodynamically constrained averaging theory for cancer growth modelling
Albrecht, Marco; Sciumè, Giuseppe; Lucarelli, Philippe; Sauter, Thomas

in IFAC-PapersOnLine (2016), 49(26), 289-294

Full Text
See detailL-plastin Ser5 phosphorylation in breast cancer cells and in vitro is mediated by RSK downstream of the ERK/MAPK pathway
Lommel, Maiti; Trairatphisan, Panuwat; Gäbler, Karoline; Laurini, Christina; Muller, Arnaud; Kaoma, Tony; Vallar, Laurent; Sauter, Thomas; Schaffner, Elisabeth

in FASEB Journal (2016)

Full Text
See detailConstraint based modelling going multicellular
Martins Conde, Patricia; Sauter, Thomas; Pfau, Thomas

in Frontiers in Molecular Biosciences (2016), 3(3),

Full Text
See detailBenchmarking procedures for high-throughput context specific reconstruction algorithms
Pacheco, Maria; Pfau, Thomas; Sauter, Thomas

in Frontiers in Physiology (2016)

Full Text
See detailA Probabilistic Boolean Network Approach for the Analysis of Cancer-Specific Signalling: A Case Study of Deregulated PDGF Signalling in GIST.
Trairatphisan, Panuwat; Wiesinger, Monique; Bahlawane, Christelle; Haan, Serge; Sauter, Thomas

in PloS one (2016), 11(5), 0156223

Top of Page

2015

Full Text
See detailConstitutive activation of oncogenic PDGFRalpha-mutant proteins occurring in GIST patients induces receptor mislocalisation and alters PDGFRalpha signalling characteristics.
Bahlawane, Christelle; Eulenfeld, Rene; Wiesinger, Monique; Wang, Jiali; Muller, Arnaud; Girod, Andreas; Nazarov, Petr V.; Felsch, Kathrin; Vallar, Laurent; Sauter, Thomas; Satagopam, Venkata; Haan, Serge

in Cell Communication and Signaling (2015), 13

Full Text
See detailRole of Calprotectin as a Modulator of the IL27-Mediated Proinflammatory Effect on Endothelial Cells
Dorosz, Susann Antonia; Ginolhac, Aurélien; Kähne, Thilo; Naumann, Michael; Sauter, Thomas; Salsmann, Alexandre; Bueb, Jean-Luc

in Mediators of Inflammation (2015), 2015

Full Text
See detailCell type-selective disease-association of genes under high regulatory load
Galhardo, Mafalda Sofia; Berninger, Philipp; Nguyen, Thanh-Phuong; Sauter, Thomas; Sinkkonen, Lasse

in Nucleic Acids Research (2015), 43(18), 8839-8855

Full Text
See detailThe oncogenic FIP1L1-PDGFRalpha fusion protein displays skewed signaling properties compared to its wild-type PDGFRalpha counterpart.
Haan, Serge; Bahlawane, Christelle; Wang, Jiali; Nazarov, Petr V.; Muller, Arnaud; Eulenfeld, Rene; Haan, Claude; Rolvering, Catherine; Vallar, Laurent; Satagopam, Venkata; Sauter, Thomas; Wiesinger, Monique

in JAK-STAT (2015), 4(1), 1062596

Full Text
See detailThe neural stem cell fate determinant TRIM32 regulates complex behavioral traits
Hillje, Anna-Lena; Beckmann, Elisabeth; Pavlou, Maria Angeliki; Jäger, Christian; Pacheco, Maria; Sauter, Thomas; Schwamborn, Jens Christian; Lewejohann, Lars

in Frontiers in Cellular Neuroscience (2015)

Full Text
See detailMultiscale model of dynamic neuromodulation integrating neuropeptide-induced signaling pathway activity with membrane electrophysiology.
Makadia, Hirenkumar K.; Anderson, Warren D.; Fey, Dirk; Sauter, Thomas; Schwaber, James S.; Vadigepalli, Rajanikanth

in Biophysical journal (2015), 108(1), 211-23

Full Text
See detailIntegrated metabolic modelling reveals cell-type specific epigenetic control points of the macrophage metabolic network
Pacheco, Maria; John, Elisabeth; Kaoma, Tony; Heinäniemi, Merja; Nicot, Nathalie; Vallar, Laurent; Bueb, Jean-Luc; Sinkkonen, Lasse; Sauter, Thomas

in BMC Genomics (2015), 16(809),

Full Text
See detailTowards improved genome-scale metabolic network reconstructions: unification, transcript specificity and beyond.
Pfau, Thomas; Pacheco, Maria; Sauter, Thomas

in Briefings in bioinformatics (2015)

Full Text
See detailComparative integrated omics: identification of key functionalities in microbial community-wide metabolic networks
Roume, Hugo; Buschart, Anna; Muller, Emilie; May, Patrick; Satagopam, Venkata; Laczny, Cedric Christian; Narayanasamy, Shaman; Lebrun, Laura; Hoopmann, Michael; Schupp, James; Gillece, John; Hicks, Nathan; Engelthaler, David; Sauter, Thomas; Keim, Paul; Moritz, Robert; Wilmes, Paul

in Biofilms and Microbiomes (2015), 1(15007),

Top of Page

2014

Full Text
See detailA mathematical model of metabolism and regulation provides a systems-level view of how Escherichia coli responds to oxygen
Ederer, M; Steinsiek, S; Stagge, S; Rolfe, MD; Ter Beek, A; Knies, D; Teixeira de Mattos, MJ; Sauter, Thomas; Green, J; Poole, RK; Bettenbrock, K; Sawodny, O

in Frontiers in Microbiology (2014), 5(124),

Full Text
See detailTranscriptomics profiling of human SGBS adipogenesis
Galhardo, Mafalda Sofia; Sinkkonen, Lasse; Berninger, Philipp; Lin, Jake; Sauter, Thomas; Heinäniemi, Merja

in Genomics Data (2014), 2

Full Text
See detailChIP-seq profiling of the active chromatin marker H3K4me3 and PPARγ, CEBPα and LXR target genes in human SGBS adipocytes
Galhardo, Mafalda Sofia; Sinkkonen, Lasse; Berninger, Philipp; Lin, Jake; Sauter, Thomas; Heinäniemi, Merja

in Genomics Data (2014), 2

Full Text
See detailBasic Regulatory Principles of Escherichia coli's Electron Transport Chain for Varying Oxygen Conditions.
Henkel, Sebastian G.; Beek, Alexander Ter; Steinsiek, Sonja; Stagge, Stefan; Bettenbrock, Katja; de Mattos, M. Joost Teixeira; Sauter, Thomas; Sawodny, Oliver; Ederer, Michael

in PloS one (2014), 9(9), 107640

Full Text
See detailIdentification of New IkappaBalpha Complexes by an Iterative Experimental and Mathematical Modeling Approach.
Konrath, Fabian; Witt, Johannes; Sauter, Thomas; Kulms, Dagmar

in PLoS computational biology (2014), 10(3), 1003528

Full Text
See detailCombinatorial regulation of lipoprotein lipase by microRNAs during mouse adipogenesis
Liivrand, Maria; Heinäniemi, Merja; John, Elisabeth; Schneider, Jochen; Sauter, Thomas; Sinkkonen, Lasse

in RNA Biology (2014), 11(1), 76-91

Full Text
See detailoptPBN: An Optimisation Toolbox for Probabilistic Boolean Networks
Trairatphisan, Panuwat; Mizera, Andrzej; Pang, Jun; Tantar, Alexandru-Adrian; Sauter, Thomas

in PLoS ONE (2014), 9(7), 980011-15

Full Text
See detailFast reconstruction of compact context-specific metabolic network models
Vlassis, Nikos; Pacheco, Maria; Sauter, Thomas

in PLoS Computational Biology (2014), 10(1), 1003424

Top of Page

2013

Full Text
See detailIntegrated analysis of transcript-level regulation of metabolism reveals disease-relevant nodes of the human metabolic network
Galhardo, Mafalda Sofia; Sinkkonen, Lasse; Berninger, Philippe; Lin, Jake; Sauter, Thomas; Heinäniemi, Merja

in Nucleic Acids Research (2013)

Full Text
See detailMathematical modelling of the Platelet-Derived Growth Factor (PDGF) signalling pathway
Mizera, Andrzej; Pang, Jun; Sauter, Thomas; Trairatphisan, Panuwat

in Proceedings of 4th Workshop on Computational Models for Cell Processes (CompMod'13) (2013)

Full Text
See detailA balancing act: Parameter estimation for biological models with steady-state measurements
Mizera, Andrzej; Pang, Jun; Sauter, Thomas; Trairatphisan, Panuwat

in Proceedings of 11th Conference on Computational Methods in Systems Biology (CMSB'13) (2013)

Full Text
See detailRecent development and biomedical applications of probabilistic Boolean networks
Trairatphisan, Panuwat; Mizera, Andrzej; Pang, Jun; Tantar, Alexandru-Adrian; Schneider, Jochen; Sauter, Thomas

in Cell Communication and Signaling (2013), 11(46),

See detailFast reconstruction of compact context-specific metabolic network models
Vlassis, Nikos; Pacheco, Maria; Sauter, Thomas

E-print/Working paper (2013)

Full Text
See detailFastcore: An algorithm for fast reconstruction of context-specific metabolic network models
Vlassis, Nikos; Pacheco, Maria; Sauter, Thomas

in Proc. 8th BeNeLux Bioinformatics Conference (2013)

Top of Page

2012

Full Text
See detailSystems analysis of transcription factor activities in environments with stable and dynamic oxygen concentrations
Rolfe, MD; Ocone, A; Stapleton, MR; Hall, S; Trotter, EW; Poole, RK; Sanguinetti, G; Green, J; SysMO-SUMO consortium; Sauter, Thomas

in Open Biology (2012), 2(7), 120091

Full Text
See detailAnalysing the role of UVB-induced translational inhibition and PP2Ac deactivation in NF-kappaB signalling using a minimal mathematical model.
Witt, Johannes; Konrath, Fabian; Sawodny, Oliver; Ederer, Michael; Kulms, Dagmar; Sauter, Thomas

in PLoS ONE (2012), 7(7), 40274

Full Text
See detailProbabilistic model checking of the PDGF signaling pathway
Yuan, Qixia; Trairatphisan, Panuwat; Pang, Jun; Mauw, Sjouke; Wiesinger, Monique; Sauter, Thomas

in Transactions on Computational Systems Biology (2012), XIV

Top of Page

2011

Full Text
See detailA systems biology approach to analyse leaf carbohydrate metabolism in Arabidopsis thaliana.
Henkel, Sebastian; Nagele, Thomas; Hormiller, Imke; Sauter, Thomas; Sawodny, Oliver; Ederer, Michael; Heyer, Arnd G.

in EURASIP Journal on Bioinformatics & Systems Biology (2011), 2011(1), 2

Full Text
See detailModeling time delay in the NFkappaB signaling pathway following low dose IL-1 stimulation.
Witt, Johannes; Barisic, Sandra; Sawodny, Oliver; Ederer, Michael; Kulms, Dagmar; Sauter, Thomas

in EURASIP Journal on Bioinformatics & Systems Biology (2011), 2011(1), 3

Full Text
See detailA study of the PDGF signaling pathway with PRISM
Yuan, Qixia; Pang, Jun; Mauw, Sjouke; Trairatphisan, Panuwat; Wiesinger, Monique; Sauter, Thomas

in Proceedings of the 3rd Workshop on Computational Models for Cell Processes (2011), EPTCS 67

Top of Page

2010

Full Text
See detailMathematical modeling of the central carbohydrate metabolism in Arabidopsis reveals a substantial regulatory influence of vacuolar invertase on whole plant carbon metabolism.
Nagele, Thomas; Henkel, Sebastian; Hormiller, Imke; Sauter, Thomas; Sawodny, Oliver; Ederer, Michael; Heyer, Arnd G.

in Plant Physiology (2010), 153(1), 260-72

Top of Page

2009

Full Text
See detailAnalysis of an apoptotic core model focused on experimental design using artificial data.
Schlatter, R.; Conzelmann, H.; Gilles, E. D.; Sawodny, O.; Sauter, Thomas

in IET Systems Biology (2009), 3(4), 255-65

Full Text
See detailON/OFF and beyond--a boolean model of apoptosis.
Schlatter, Rebekka; Schmich, Kathrin; Avalos Vizcarra, Ima; Scheurich, Peter; Sauter, Thomas; Borner, Christoph; Ederer, Michael; Merfort, Irmgard; Sawodny, Oliver

in PLoS Computational Biology (2009), 5(12), 1000595

Full Text
See detailMechanism of PP2A-mediated IKK beta dephosphorylation: a systems biological approach.
Witt, Johannes; Barisic, Sandra; Schumann, Eva; Allgower, Frank; Sawodny, Oliver; Sauter, Thomas; Kulms, Dagmar

in BMC Systems Biology (2009), 3

Top of Page

2008

Full Text
See detailAnalyse der evolutiven Adaptation am Beispiel einer pyruvat-auxotrophen Escherichia coli-Mutante
Feuer, Ronny; Ederer, Michael; Gilles, Ernst Dieter; Sprenger, Georg; Sawodny, Oliver; Sauter, Thomas

in Automatisierungstechnik (2008), 56

Top of Page

2007

See detailCorrelation between growth rates, EIIACrr phosphorylation, and intracellular cyclic AMP levels in Escherichia coli K-12.
Bettenbrock, Katja; Sauter, Thomas; Jahreis, Knut; Kremling, Andreas; Lengeler, Joseph W.; Gilles, Ernst-Dieter

in Journal of Bacteriology (2007), 189(19), 6891-900

See detailMethods for analysis of evolutive adaptation of E. coli
Feuer, Ronny; Ederer, Michael; Trachtmann, Natalie; Sauter, Thomas; Gilles, Ernst Dieter; Sprenger, Georg; Sawodny, Oliver

in Proceedings of the SICE Annual Conference, September 17-20, 2007 Kagawa University, Takamatsu City, Japan (2007)

See detailModeling and Analysis of UVB Influence on IL-1 induced NF-kappaB Signaling
Witt, Johannes; Husser, Sebastian; Kulms, Dagmar; Barisic, Sandra; Sawodny, Oliver; Sauter, Thomas

in Proceedings of the FOSBE, September 9-12, Stuttgart, Germany (2007)

Top of Page

2006

See detailA quantitative approach to catabolite repression in Escherichia coli.
Bettenbrock, Katja; Fischer, Sophia; Kremling, Andreas; Jahreis, Knut; Sauter, Thomas; Gilles, Ernst-Dieter

in Journal of Biological Chemistry (2006), 281(5), 2578-84

See detailA domain-oriented approach to the reduction of combinatorial complexity in signal transduction networks.
Conzelmann, Holger; Saez-Rodriguez, Julio; Sauter, Thomas; Kholodenko, Boris N.; Gilles, Ernst D.

in BMC Bioinformatics (2006), 7

See detailSensitivity analysis of programmed cell death and implications for crosstalk phenomena during Tumor Necrosis Factor stimulation
Eissing, Thomas; Bullinger, Eric; Waldherr, Steffen; Gondro, Cedric; Sawodny, Oliver; Allgöwer, Frank; Scheurich, Peter; Sauter, Thomas

in Proceedings of IEEE International Conference on Control Applications (CCA), October 4-6, 2006, Technische Universität München, Germany (2006)

See detailModeling the VPAC2-activated cAMP/PKA signaling pathway: from receptor to circadian clock gene induction.
Hao, Haiping; Zak, Daniel E.; Sauter, Thomas; Schwaber, James; Ogunnaike, Babatunde A.

in Biophysical Journal (2006), 90(5), 1560-71

Top of Page

2004

See detailReduction of mathematical models of signal transduction networks: simulation-based approach applied to EGF receptor signalling.
Conzelmann, H.; Saez-Rodriguez, J.; Sauter, Thomas; Bullinger, E.; Allgower, F.; Gilles, E. D.

in Systems biology (2004), 1(1), 159-69

See detailTowards whole cell "in silico" models for cellular systems: model set-up and model validation
Kremling, A.; Bettenbrock, K.; Fischer, S.; Ginkel, M.; Sauter, Thomas; Gilles, E. D.

in Lecture Notes in Control and Information Sciences: Proceedings of the first multidisciplinary international symposium on Positive Systems (2004)

See detailTime hierarchies in the Escherichia coli carbohydrate uptake and metabolism.
Kremling, A.; Fischer, S.; Sauter, Thomas; Bettenbrock, K.; Gilles, E. D.

in Bio Systems (2004), 73(1), 57-71

See detailA benchmark for methods in reverse engineering and model discrimination: problem formulation and solutions.
Kremling, Andreas; Fischer, Sophia; Gadkar, Kapil; Doyle, Francis J.; Sauter, Thomas; Bullinger, Eric; Allgower, Frank; Gilles, Ernst D.

in Genome Research (2004), 14(9), 1773-85

See detailDetailed Mathematical Modeling of Metabolic and Regulatory Networks
Sauter, Thomas; Bullinger, E.

in BIOforum Europe (2004), 02

Top of Page

2003

See detailAn approach for dividing models of biological reaction networks into functional units
Ederer, M.; Sauter, Thomas; Bullinger, E.; Gilles, E. D.; Allgöwer, F.

in Simulation (2003), 79

Top of Page

2001

See detailBiosystems Engineering: Applying methods from systems theory to biological systems
Kremling, A.; Sauter, Thomas; Bullinger, E.; Ederer, M.; Allgöwer, F.; Gilles, E. D.

in Proceedings of the 2nd International Conference on Systems Biology 4.-7.11.2001, Pasadena (2001)

Top of Page