Ganesh Manoharan

Ganesh Manoharan

Postdoctoral researcher

Faculty or Centre Faculty of Science, Technology and Communication
Research Unit RU Life Sciences
Postal Address Campus Belval, Université du Luxembourg
7, Avenue des Hauts Fourneaux
L-4362 Esch-sur-Alzette
Campus Office BioTech I, 3.05B
Email
Telephone (+352) 46 66 44 6025
Fax (+352) 46 66 44 36025
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2019

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See detailHigh-throughput amenable fluorescence-assays to screen for calmodulin-inhibitors
Manoharan, Ganesh Babu; Kopra, Kari; Eskonen, Ville; Harma, Harri; Abankwa, Daniel

in Analytical Biochemistry (2019), 572

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2018

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See detailThiazole- and selenazole-comprising high-affinity inhibitors possess bright microsecond-scale photoluminescence in complex with protein kinase CK2.
Vahter, Jurgen; Viht, Kaido; Uri, Asko; Manoharan, Ganesh Babu; Enkvist, Erki

in Bioorganic & medicinal chemistry (2018), 26(18), 5062-5068

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2016

See detailBifunctional Ligands for Inhibition of Tight-Binding Protein–Protein Interactions
Ivan, Taavi; Enkvist, Erki; Viira, Birgit; Manoharan, Ganesh Babu; Raidaru, Gerda; Pflug, Alexander; Alam, Kazi Asraful; Zaccolo, Manuela; Engh, Richard Alan; Uri, Asko

in Bioconjugate Chemistry (2016), 27(8), 1900-1910

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See detailCombining chemical and genetic approaches for development of responsive FRET-based sensor systems for protein kinases
Manoharan, Ganesh Babu; Enkvist, Erki; Uri, Asko

in Biophysical Chemistry (2016)

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See detailPhosphorylation of Notch1 by Pim kinases promotes oncogenic signaling in breast and prostate cancer cells
Santio, Niina M.; Landor, Sebastian K.-J.; Vahtera, Laura; Yla-Pelto, Jani; Paloniemi, Elina; Imanishi, Susumu Y.; Corthals, Garry; Varjosalo, Markku; Manoharan, Ganesh Babu; Uri, Asko; Lendahl, Urban; Sahlgren, Cecilia; Koskinen, Paivi J.

in Oncotarget (2016), 7(28), 43220-43238

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2015

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See detailPIM kinase-responsive microsecond-lifetime photoluminescent probes based on selenium-containing heteroaromatic tricycle
Ekambaram, Ramesh; Manoharan, Ganesh Babu; Enkvist, Erki; Ligi, Kadri; Knapp, Stefan; Uri, Asko

in RSC Advances (2015)

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See detailFRET-based screening assay using small-molecule photoluminescent probes in lysate of cells overexpressing RFP-fused protein kinases
Manoharan, Ganesh Babu; Enkvist, Erki; Kasari, Marje; Viht, Kaido; Zenn, Michael; Prinz, Anke; Filhol, Odile; Herbergb, Friedrich W.; Uri, Asko

in Analytical Biochemistry (2015)

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2014

See detailBenzoselenadiazole-based responsive long-lifetime photoluminescent probes for protein kinases
Ekambaram, Ramesh; Enkvist, Erki; Manoharan, Ganesh Babu; Ugandi, Mihkel; Kasari, Marje; Viht, Kaido; Knapp, Stefan; Issinger, Olaf-Georg; Uri, Asko

in Chemical Communications (2014)

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2012

See detailActive site analysis of cis-epoxysuccinate hydrolase from Nocardia tartaricans using homology modeling and site-directed mutagenesis
Vinayagam, Vasu; Jayaraman, Kumaresan; Manoharan, Ganesh Babu; Sankaranarayanan, Meenakshisundaram

in Applied Microbiology and Biotechnology (2012), 93(6), 23772386

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