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Prof. Dr. Daniel Abankwa

Daniel Abankwa

Full professor in Cellular Tumour Biology

Faculty or Centre Faculty of Science, Technology and Medicine
Department Department of Life Sciences and Medicine
Postal Address Campus Belval, Université du Luxembourg
7, Avenue des Hauts Fourneaux
L-4362 Esch-sur-Alzette
Campus Office BioTech I, 3.05F
Telephone (+352) 46 66 44 6897

Last updated on: Thursday, 17 October 2019

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See detailBruceine D Identified as a Drug Candidate against Breast Cancer by a Novel Drug Selection Pipeline and Cell Viability Assay.
Cipriani, Claudia; Pires Pacheco, Maria Irene; Kishk, Ali; Wachich, Maryem; Abankwa, Daniel; Schaffner-Reckinger, Elisabeth; Sauter, Thomas

in Pharmaceuticals (Basel, Switzerland) (2022), 15(2),

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See detailPotential of phenothiazines to synergistically block calmodulin and reactivate PP2A in cancer cells
Manoharan, Ganesh Babu; Okutachi, Sunday; Abankwa, Daniel

in PLoS ONE (2022)

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See detailDrug targeting opportunities en route to Ras nanoclusters.
Pavic, Karolina; Chippalkatti, Rohan; Abankwa, Daniel

in Advances in cancer research (2022), 153

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See detailNRAS is unique among RAS proteins in requiring ICMT for trafficking to the plasma membrane
Ahearn, Ian M.; Court, Helen R.; Siddiqui, Farid; Abankwa, Daniel; Philips, Mark R.

in Life Science Alliance (2021)

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See detailPromotion of cancer cell stemness by Ras
Chippalkatti, Rohan; Abankwa, Daniel

in Biochemical Society Transactions (2021)

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See detailA Pharmacophore Model for SARS-CoV-2 3CLpro Small Molecule Inhibitors and in Vitro Experimental Validation of Computationally Screened Inhibitors
Glaab, Enrico; Manoharan, Ganesh Babu; Abankwa, Daniel

in Journal of Chemical Information and Modeling (2021), 61(8), 4082-4096

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See detailA covalent calmodulin inhibitor as a tool to study cellular mechanisms of K-Ras-driven stemness
Okutachi, Sunday Ojochegbe; Manoharan, Ganesh Babu; Kiriazis, Alexandros; Laurini, Christina; Catillon, Marie; McCormick, Franck; Yli-Kauhaluoma, Jari; Abankwa, Daniel

in Frontiers in Cell and Developmental Biology (2021)

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See detailFLIM-FRET Analysis of Ras Nanoclustering and Membrane-Anchorage.
Parkkola, Hanna; Siddiqui, Farid Ahmad; Oetken-Lindholm, Christina; Abankwa, Daniel

in Methods in molecular biology (Clifton, N.J.) (2021), 2262

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See detailElaiophylin Is a Potent Hsp90/ Cdc37 Protein Interface Inhibitor with K-Ras Nanocluster Selectivity
Siddiqui, Farid A.; Vukic, Vladimir; Salminen, Tiina A.; Abankwa, Daniel

in Biomolecules (2021)

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See detailMechanisms of Ras Membrane Organization and Signaling: Ras Rocks Again.
Abankwa, Daniel; Gorfe, Alemayehu A.

in Biomolecules (2020), 10(11),

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See detailProceedings of the AI4Health Lecture Series (2020)
Schommer, Christoph; Sauter, Thomas; Pang, Jun; Abankwa, Daniel

Scientific Conference (2020)

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See detailPDE6D Inhibitors with a New Design Principle Selectively Block K‑Ras Activity
Siddiqui, Farid A.; Alam, Catharina; Rosenqvist, Petja; Ora, Mikko; Sabt, Ahmed; Manoharan, Ganesh Babu; Bindu, Lakshman; Okutachi, Sunday Ojochegbe; Catillon, Marie; Taylor, Troy; Abdelhafez, Omaima M.; Lönnberg, Harri; Stephen, Andrew G.; Papageorgiou, Anastassios C.; Virta, Pasi; Abankwa, Daniel

in ACS Omega (2020), 5(1), 832-842

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See detailA subset of flavaglines inhibits KRAS nanoclustering and activation.
Yurugi, Hajime; Zhuang, Yinyin; Siddiqui, Farid A.; Liang, Hong; Rosigkeit, Sebastian; Zeng, Yongpeng; Abou-Hamdan, Hussein; Bockamp, Ernesto; Zhou, Yong; Abankwa, Daniel; Zhao, Wenting; Désaubry, Laurent; Rajalingam, Krishnaraj

in Journal of cell science (2020), 133(12),

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See detailHigh-throughput amenable fluorescence-assays to screen for calmodulin-inhibitors
Manoharan, Ganesh Babu; Kopra, Kari; Eskonen, Ville; Harma, Harri; Abankwa, Daniel

in Analytical Biochemistry (2019), 572

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See detailMedium-Throughput Detection of Hsp90/Cdc37 Protein–Protein Interaction Inhibitors Using a Split Renilla Luciferase-Based Assay
Siddiqui, Farid A.; Parkkola, Hanna; Manoharan, Ganesh Babu; Abankwa, Daniel

in SLAS Discovery (2019)

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See detailTargeting prohibitins at the cell surface prevents Th17-mediated autoimmunity.
Buehler, Ulrike; Schulenburg, Katharina; Yurugi, Hajime; Solman, Maja; Abankwa, Daniel; Ulges, Alexander; Tenzer, Stefan; Bopp, Tobias; Thiede, Bernd; Zipp, Frauke; Rajalingam, Krishnaraj

in The EMBO journal (2018), 37(16),

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See detailrapalogs can promote cancer cell stemness in vitro in a Galectin-1 and H-ras-dependent manner
Posada, IMD; Lectez, B; Sharma, M; Oetken-Lindholm, C; Yetukuri, L; Zhou, Y; Aittokallio, T; Abankwa, Daniel

in Oncotarget (2017), Vol. 8((No. 27)), 44550-44566

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See detailOpposite feedback from mTORC1 to H-ras and K-ras4B downstream of SREBP1
Posada, IMD; Lectez, B; Siddiqui, FA; Oetken-Lindholm, C; Sharma, M; Abankwa, Daniel

in Scientific Reports (2017)

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See detailTailored Approaches in Drug Development and Diagnostics: From Molecular Design to Biological Model Systems
Sahlgren, C; Meinander, A; Zhang, H; Cheng, F; Preis, M; Xu, C; Salminen, TA; Toivola, D; Abankwa, Daniel; Rosling, A; Karaman, DS; Salo-Ahen, OMH; Österbacka, R; Eriksson, JE; Willför, S; Petre, I; Peltonen, J; Leino, R; Johnson, M; Rosenholm, J; Sandler, N

in Advanced Healthcare Materials (2017)

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