Dr. Tony Heurtaux

Tony Heurtaux

Research scientist

Faculty or Centre Faculty of Science, Technology and Medicine
Department Department of Life Sciences and Medicine
Postal Address Campus Belval, Université du Luxembourg
7, Avenue des Hauts Fourneaux
L-4362 Esch-sur-Alzette
Campus Office BioTech I, 1.04C
Telephone (+352) 46 66 44 5144
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See detailSingle-cell transcriptional profiling and gene regulatory network modeling in Tg2576 mice reveal gender-dependent molecular features preceding Alzheimer-like pathologies
Ali, Muhammad; Huarte, Oihane; Heurtaux, Tony; Garcia, Pierre; Rodriguez, Beatriz Pardo; Grzyb, Kamil; Halder, Rashi; Skupin, Alexander; Buttini, Manuel; Glaab, Enrico

in Molecular Neurobiology (2022), in press (doi:10.1007/s12035-022-02985-2)(in press),

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See detailThe Multifaceted Neurotoxicity of Astrocytes in Ageing and Age-Related Neurodegenerative Diseases: A Translational Perspective.
Bouvier, David S; Fixemer, Sonja; Heurtaux, Tony; Jeannelle, Felicia; Frauenknecht, Katrin B M; Mittelbronn, Michel

in Frontiers in Physiology (2022)

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See detailNeurodegeneration and neuroinflammation are linked, but independent of a-synuclein inclusions, in a seeding/spreading mouse model of Parkinson's disease
Garcia, Pierre; Wemheuer, W.; Uriarte, O.; Michelucci, Alessandro; Masuch, A.; Brioschi, S.; Weihofen, A.; Koncina, Eric; Coowar, Djalil; Heurtaux, Tony; Glaab, Enrico; Balling, Rudolf; Sousa, C.; Kaoma, T.; Nicot, N.; Pfander, T.; Schulz-Schaeffer, W.; Allouche, A.; Fischer, N.; Biber, K.; Mittelbronn, Michel; Ostaszewski, Marek; Schmit, Kristopher; Buttini, Manuel

in Glia (2022)

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See detailNormal and Pathological NRF2 Signalling in the Central Nervous System
Heurtaux, Tony; Bouvier, David S; Benani, Alexandre; Helgueta Romero, Sergio; Frauenknecht, Katrin B M; Mittelbronn, Michel; Sinkkonen, Lasse

in Antioxidants (2022), 11(8), 1426

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See detailReview of Current Human Genome-Scale Metabolic Models for Brain Cancer and Neurodegenerative Diseases.
Kishk, Ali; Pires Pacheco, Maria Irene; Heurtaux, Tony; Sinkkonen, Lasse; Pang, Jun; Fritah, Sabrina; Niclou, Simone; Sauter, Thomas

in Cells (2022), 11(16),

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See detailMicrogliosis: a double-edged sword in the control of food intake
Salvi, Juliette; Andreoletti, Pierre; Audinat, Etienne; Balland, Eglantine; Ben Fradj, Selma; Cherkaoui-Malki, Mustapha; Heurtaux, Tony; Lienard, Fabienne; Nedelec, Emmanuelle; Rovere, Carole; Savary, Stéphane; Vejux, Anne; Trompier, Doriane; Benani, Alexandre

in FEBS Journal (2022)

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See detailAn archaeal compound as a driver of Parkinson’s disease pathogenesis
Trezzi, Jean-Pierre; Aho, Velma; Jäger, Christian; Schade, Sebastian; Janzen, Annette; Hickl, Oskar; Kunath, Benoit; Thomas, Melanie; Schmit, Kristopher; Garcia, Pierre; Sciortino, Alessia; Martin-Gallausiaux, Camille; Halder, Rashi; Huarte, Oihane Uriarte; Heurtaux, Tony; Heins-Marroquin, Ursula; Gomez-Giro, Gemma; Weidenbach, Katrin; Delacour, Lea; Laczny, Cedric Christian; Novikova, Polina; Ramiro-Garcia, Javier; Singh, Randolph; Andújar, Begoña Talavera; Lebrun, Laura; Daujeumont, Annegrait; Habier, Janine; Dong, Xiangyi; Gavotto, Floriane; Heintz-Buschart, Anna; Schneider, Jochen; Jehmlich, Nico; Bergen, Martin Von; Schymanski, Emma; Schmitz, Ruth; Schwamborn, Jens Christian; Glaab, Enrico; Linster, Carole; Kitami, Toshimori; Buttini, Manuel; May, Patrick; Trenkwalder, Claudia; Oertel, Wolfgang; Mollenhauer, Brit; Wilmes, Paul

E-print/Working paper (2022)

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See detailApomorphine Reduces A53T α‑Synuclein‑Induced Microglial Reactivity Through Activation of NRF2 Signalling Pathway
Heurtaux, Tony; Kirchmeyer, Mélanie; Koncina, Eric; Richart, Lorraine; Uriarte Huarte, Oihane; Schohn, Herve; Mittelbronn, Michel

in Cellular and Molecular Neurobiology (2021)

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See detailSingle-Cell Transcriptomics and In Situ Morphological Analyses Reveal Microglia Heterogeneity Across the Nigrostriatal Pathway
Uriarte Huarte, Oihane; Kyriakis, Dimitrios; Heurtaux, Tony; Pires-Afonso, Yolanda; Grzyb, Kamil; Halder, Rashi; Buttini, Manuel; Skupin, Alexander; Mittelbronn, Michel; Michelucci, Alessandro

in Frontiers in Immunology (2021)

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See detailPostprandial hyperglycemia stimulates neuroglial plasticity in hypothalamic POMC neurons after a balanced meal
Nuzzaci, Danaé; Cansell, Céline; Liénard, Fabienne; Nédélec, Emmanuelle; Ben Fradj, Selma; Castel, Julien; Foppen, Ewout; Denis, Raphael; Grouselle, Dominique; Laderrière, Amélie; Lemoine, Aleth; Mathou, Alexia; Tolle, Virginie; Heurtaux, Tony; Fioramonti, Xavier; Audinat, Etienne; Pénicaud, Luc; Nahon, Jean-Louis; Rovère, Carole; Benani, Alexandre

in Cell Reports (2020), 30

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See detailAlpha-Synuclein Proteins Promote Pro-Inflammatory Cascades in Microglia: Stronger Effects of the A53T Mutant.
Hoenen, Claire; Gustin, Audrey; Birck, Cindy; Kirchmeyer, Mélanie; Beaume, Nicolas; Felten, Paul; Grandbarbe, Luc; Heuschling, Paul; Heurtaux, Tony

in PLoS ONE (2016)

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See detailTranscriptomic analyses of primary astrocytes under TNFα treatment
Birck, Cindy; Koncina, Eric; Heurtaux, Tony; Glaab, Enrico; Michelucci, Alessandro; Heuschling, Paul; Grandbarbe, Luc

in Genomics Data (2015), 7

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See detailInflammation Promotes a Conversion of Astrocytes into Neural Progenitor Cells via NF-κB Activation
Gabel, Sebastien; Koncina, Eric; Dorban, Gauthier; Heurtaux, Tony; Birck, Cindy; Glaab, Enrico; Michelucci, Alessandro; Heuschling, Paul; Grandbarbe, Luc

in Molecular Neurobiology (2015), 53(8), 5041-5055

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See detailNLRP3 Inflammasome Is Expressed and Functional in Mouse Brain Microglia but Not in Astrocytes.
Gustin, Audrey; Kirchmeyer, Mélanie; Koncina, Eric; Felten, Paul; Losciuto, Sophie; Heurtaux, Tony; Tardivel, A; Heuschling, Paul; Dostert, Catherine

in PLoS ONE (2015), 10(6),

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See detailTocopherol derivative TFA-12 promotes myelin repair in experimental models of multiple sclerosis.
Blanchard, Benoit; Heurtaux, Tony; Nait Oumesmar, Brahim

in Journal of Neuroscience (2013), 33(28), 11633-42

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See detailAn efficient method to limit microglia-dependent effects in astroglial cultures.
Losciuto, Sophie; Dorban, Gauthier; Gabel, Sébastien; Gustin, Audrey; Hoenen, Claire; Grandbarbe, Luc; Heuschling, Paul; Heurtaux, Tony

in Journal of Neuroscience Methods (2012), 207(1), 59-71

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See detailMicroglial activation depends on beta-amyloid conformation: role of the formylpeptide receptor 2
Heurtaux, Tony; Michelucci, Alessandro; Losciuto, Sophie; Gallotti, Christian; Felten, Paul; Dorban, Gauthier; Grandbarbe, Luc; Morga, Eleonora; Heuschling, Paul

in Journal of Neurochemistry (2010), 114(2), 576-586

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See detailCharacterization of the microglial phenotype under specific pro-inflammatory and anti-inflammatory conditions: Effects of oligomeric and fibrillar amyloid-beta
Michelucci, Alessandro; Heurtaux, Tony; Grandbarbe, Luc; Morga, Eleonora; Heuschling, Paul

in Journal of Neuroimmunology (2009), 210(1-2), 3-12

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See detailNotch signaling modulates the activation of microglial cells
Grandbarbe, Luc; Michelucci, Alessandro; Heurtaux, Tony; Hemmer, Karin; Morga, Eleonora; Heuschling, Paul

in Glia (2007), 55(15), 1519-30

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