Some of our research projects
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MIMY EMpowerment through liquid Integration of Migrant Youth in vulnerable conditions
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Goals12 multinational partners aim to improve the situation of young migrants in vulnerable conditions throughout Europe by examining the effectiveness of integration policies in an interdisciplinary research endeavor. MethodMIMY applies a comprehensive mixed-methods approach combining various quantitative and qualitative methods on different levels of analysis. Additionally, the project actively engages young migrants to include their voice within migration research, mainly through the involvement of peer researchers. ImplementationThe project will examine processes of integration of young non-EU migrant in 18 local contexts, 2 in each of the 9 European countries involved. Each case study represents a specific local context, but may also target a specific representative subgroup. WhereThe action is covering 2 case studies each in Luxembourg, Germany, United Kingdom, Sweden, Norway, Italy, Poland, Romania, and Hungary while benefiting from the support of the European Confederation of Youth Clubs. Uni.lu roleUni.lu coordinates (including project management and scientific coordination) the MIMY project, leads the participatory action research activities and conducts the case studies in Luxembourg. Success stories and updates
The project has received funding from the European Union’s Horizon 2020 research and innovation programme under the grant agreement No 870700. |
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WorkYP Working, Yet Poor |
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GoalsWorkYP aims to investigate on the increasing social trend of working people at risk or below the poverty line in view of attenuating divergent trends across Europe. Such attenuation would effectively prevent the risk of social dumping and reduce economic shocks. MethodComparative and multi-disciplinary perspectives are applied when analyzing four pre-identified clusters of particularly vulnerable and underrepresented persons (VUPs) which disadvantaged conditions impede full enjoyment of EU citizenship. ImplementationThe WorkYP Consortium plans to elaborate the necessary theoretical frameworks, initiate public debates, provide policy recommendations and practical tools to deliver a sound and easily understandable concept of EU social citizenship. WhereThe action is covering case studies in seven countries (Sweden, Italy, The Netherlands, Belgium, Luxembourg, Germany, and Poland) selected on the basis of their geographical location, social system and legal order. At the same time, the project is supported by three Social Rights Institutions. Uni.lu roleUni.lu coordinates (including project management and ethics) the WorkYP project, leads the investigatory activities of economists and sociologists of all academic partners and runs the societal impact assessment which aims to identify best practices for tackling in-work poverty. Success stories and updatesArticle "In-work poverty in times of pandemic"
The project has received funding from the European Union’s Horizon 2020 research and innovation programme under the grant agreement No 870619. |
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imSAVAR |
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GoalsThe project aims to improve the ability to predict adverse immune-related toxicities and establish a standard approach to immune safety. MethodBy developing a platform that consists of processes for developing nonclinical assessment strategies as well as models that represent the complexity of diseases and predict the immune related adverse events, imSAVAR improves the prediction of the transferability of safety and efficacy of immunomodulators from pre-clinical models to first-in-human studies. ImplementationThe imSAVAR platform is based upon in vitro and in vivo case studies for prioritized therapeutic modalities while considering also the input of multiple stakeholders, including regulatory agencies. WhereThe action is covering case studies in seven countries (Sweden, Italy, The Netherlands, Belgium, Luxembourg, Germany, and Poland) selected on the basis of their geographical location, social system and legal order. At the same time, the project is supported by three Social Rights Institutions. Uni.lu roleUni.lu is co-leading the development and deployment of the data and knowledge platform (i.e. data management plan, link to sample management system, data harmonization) and contributes to the biomarker (molecular profiling) development of immune cells. Success stories and updates
This project has received funding from the Innovative Medicines Initiative 2 Joint Undertaking (JU) under grant agreement No 853988. The JU receives support from the European Union’s Horizon 2020 research and innovation programme and EFPIA and JDRF INTERNATIONAL. |
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ImmUniverse |
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GoalsThe transdisciplinary ImmUniverse consortium aims to advance the diagnosis, management and treatment for ulcerative colitis and atopic dermatitis. MethodThe project studies the role of crosstalk between tissue micro-environment and immune cells in disease progression and response to therapy. ImplementationBy implementing non-invasive liquid-biopsy methodologies combined with circulating biomarker assays, ImmUniverse envisages the replacement of invasive biopsy procedures that make up the current choice in clinical surveillance of immune-mediated diseases. WhereThe expertise and technological support of the ImmUniverse international partnership is complemented by clinical studies across 6 European countries (BE, DE, DK, FR, NL and UK). Uni.lu roleUni.lu is responsible for establishing and operating the ImmUniverse virtual biobank platform and the data and analysis portal. Furthermore, Prof. Dr. Schneider’s team is also leading the implementation of ulcerative colitis and atopic dermatitis disease maps while ensuring data security. Success stories and updates
This project has received funding from the Innovative Medicines Initiative 2 Joint Undertaking (JU) under grant agreement No 853995 with EU Horizon 2020 EFPIA support. |
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Cities2030 |
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Goals41 partners forming the international consortium of Cities2030 work towards transforming and restructuring the way systems produce, transport and supply, recycle and reuse food in the 21st century. MethodBuild on a “Foot+Tech Connect” approach, the complex holistic system methodology, is citizen-driven and considers all relevant elements, including Social Sciences and Humanities (SSH). The project foresees a set of activities for policy framework development and innovative action which engages and activates all agents of the urban food supply chain, providing thus an undisputable proof of effective urban food systems and ecosystems. ImplementationCities2030 puts forward a multiple of tools such as a community of practice (the Cities and Regions Food Systems Alliance) supported by a digital platform, reaching all over Europe and beyond. WhereThe cities of Bremerhaven, Bruges, Haarlem, Iasi, Quart de Poblet, Murska Sobota, Seinajoki, Velika Gorica, Vejle, Vicenza together with the regions of Troodos and Vidzeme will act as front-runners for policy system thinking activities and living labs. Uni.lu roleProf. Dr. Engel’s team contributes to the research parts of the project that touch the main focus areas of the SECAN-Lab group, namely research topics like privacy by distribution, network and system security, SCADA and cyber security, Big Data, IoT, vehicular communication and multimodal traffic management, wireless networks and mobile security. The living lab concept and the project plans are crucial to implement it at policy level as well. Success stories and updates
The project has received funding from the European Union’s Horizon 2020 research and innovation programme under the Grant Agreement No 101000640. |
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MEESST |
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GoalsMEESST aims to make safe atmospheric (re-)entry at hypersonic flows a reality by implementing the first demonstrator of active magnetic shielding. The project will tackle two associated issues: significant thermal loads on the spacecraft surface and radio communication blackouts. MethodBeyond accurate models for communication physics, the MEESST consortium will develop a new generation of superconducting magnets that would be effective in manipulating the plasma around a (re)entry space vehicle while be compact and lighter enough to be carry onboard. ImplementationA dual communication channel – hypersonic fluid dynamics model will be compared with experimental data from the prototype that will be tested in on-ground plasma facilities. WhereWhile lab experimental investigations will be taking place in plasma testing facilities in Germany, the manufacturing of the prototype will be a French-German collaboration. Uni.lu roleThe Uni.lu team, led by Dr. Thoemel and Dr. Merlano Duncan, will focus on the modelling of the plasma and the communication channel physics. Furthermore, Uni.lu will lead the efforts of linking these models with other project software and of validating the simulation results against experimental data. Success stories and updates
The project has received funding from the European Union’s Horizon 2020 research and innovation programme under the Grant Agreement No 899298. |
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GoalsThe ADMORPH project aims to provide an effective solution to system faults and cyber-attacks, for both traditional mission- and safety-critical embedded systems and for their autonomous and networked counterparts: Cyber Physical Systems (of Systems) - CPS(oS). MethodThe project partners will demonstrate fault and intrusion tolerance through a novel, holistic approach for systematically designing, analyzing, and run-time managing embedded computer systems in mission- or safety-critical CPS(oS) that use the concept of system adaptivity in the form of dynamic task-to-resource allocation. ImplementationThe methodologies, methods and tools developed under ADMORPH will be evaluated using radar surveillance systems, autonomous aerospace systems, and urban guided transportation management and control systems domains as industrial use cases. WhereWhile the adaptivity technology will be tested via simulated environments in Ireland, the Netherlands and the Czech Republic, the project results and outcomes will be made available to the community at large. Uni.lu roleUnder the guidance of Dr. Völp, Uni.lu leads the efforts on developing the adaptation building blocks (e.g, methods, protocols, tools and techniques) required for an effective CPS(oS) response to extreme, disruptive events (WP2). Furthermore, Uni.lu will disseminate the project results to its PhD candidates through relevant courses, to the general public through outreach events, such as science.lu, and to the affiliated national and international industry. Success stories and updates
The project has received funding from the European Union’s Horizon 2020 research and innovation programme under the grant agreement No 871259. |
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01/01/2020 – 31/12/2022 |
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GoalsSinFonia aims to make the long-sought-after goal of producing alternative and safer fluorinated polymers from renewable substrates a reality. This will be achieved by designing sustainable bioprocesses and rewiring the metabolically versatile, non-pathogenic soil bacterium Pseudomonas putida to incorporate inorganic fluorine into its metabolism. MethodBy exploiting the bacterium’s native machinery, SinFonia applies a variety of innovative methodologies (in silico design, genome engineering, adaptive laboratory evolution, bioprocess and advanced metabolic engineering) to generate novel fluoropolymers from an inexpensive and safe salt, sodium fluoride, and sugar. ImplementationThe SinFonia consortium will in the end showcase and assess the industrial applicability of two novel fluoropolymers with varying side chain lengths. The fluorine will provide the polymer with its durability, water and oil-repellency, thermostability, and conductivity properties, while side chain length will determine properties like its hardness, cross-linkability, and flexibility. The fluoropolymers are anticipated to be utilized in self-cleaning surfaces, low-surface-energy coatings, bio-based lubricants, membranes for fuel cells, and anti-fouling materials. WhereWith a partnership formed out of 3 research organizations, 4 academic institutions, 1 large industry and 5 SMEs from 10 European countries, the SinFonia consortium covers not only the required scientific experts but also the entire chain to produce, characterize, and bring the novel fluoropolymers to market. Experimental, industrial testing and scale-up activities will take place in France, Estonia, UK, Ireland and the Netherlands. Uni.lu roleDr. Linster’s research group will lead the metabolic profiling and metabolite repair-based strain optimization efforts. Additionally, expert advice on unknown compound identification (e.g. fluorometabolites) from mass spectral data will be provided by the Environmental Cheminformatics group of Uni.lu. Success stories and updates
The project has received funding from the European Union’s Horizon 2020 research and innovation programme under the grant agreement No 814418. |
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GoalsThe CONNECT project aims to enable the study of a complete organ system, including the connectivity of the nervous system in view of improving predictions about the onset of Neurodegenerative Diseases (NDDs) and consequently the development of personalized treatment concepts. MethodThe project consortium will model the functioning of the human nervous systems in a chip-based in vitro model using state-of-the-art stem cell technology, nanofabrication and tissue engineering. ImplementationThe artificial platform developed under the CONNECT project will be tested using working hypotheses for the evolution and functioning of the Parkinson’s disease, the second most common NDD. WhereThe strongly complementary of the 7 European partners is demonstrated by the specific expertise brought to the CONNECT project: tissue engineering (Luxembourg), stem cell biology (UK), microfluidics (Finland), nanofabrication and translational neurobiology (the Netherlands) and advanced imaging (Belgium). Uni.lu roleDr. Schwamborn’s team will lead the efforts associated with the generation of midbrains/hindbrains bringing in extensive expertise in human stem cells differentiation, the generation of brain organoids and the detection of disease specific phenotypes in the respective in vitro systems. Success stories and updatesfet-proactive-connect.com/news
The project has received funding from the European Union’s Horizon 2020 research and innovation programme under the grant agreement No 824070. |
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